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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

RUCAPARIB-200MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ruparib 200 Tablet

Ruparib 200 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of ovarian cancer, fallopian tube, and primary peritoneal cancer. It is also indicated in the treatment of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments.
 
Ruparib 200 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer. 
 
In some cases, Ruparib 200 Tablet may cause side effects such as fatigue, nausea, vomiting, diarrhoea, decreased or loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, inform your doctor.
 
Let the doctor know if you are allergic to any of the components in Ruparib 200 Tablet . Ruparib 200 Tablet is not recommended for use in children as the safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Ruparib 200 Tablet

Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer, Prostate cancer

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Ruparib 200 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of prostate cancer. It is also used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube, and primary peritoneal cancer that have returned in adults who have partially or completely responded to other chemotherapy treatments and in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Ruparib 200 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ruparib 200 Tablet

Ovarian cancer:

  • Nausea
  • Vomiting
  • Tiredness
  • Stomach pain
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Sunburn
  • Heartburn
  • Difficulty breathing

Prostate cancer:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Fatigue
  • Anaemia
  • Decreased appetite

Drug Warnings

Do not take Ruparib 200 Tablet if you are allergic to any of its components or if you are pregnant or breastfeeding. Ruparib 200 Tablet may cause serious side effects like bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Seek immediate medical attention if you experience weakness, weight loss, fever, frequent infections, blood in urine or stools, feeling very tired, shortness of breath, and bleeding or bruising more easily. Consult your doctor immediately if you become pregnant during treatment with Ruparib 200 Tablet . Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
RucaparibZiprasidone
Critical
RucaparibSotalol
Severe

Drug-Drug Interactions

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RucaparibZiprasidone
Critical
How does the drug interact with Ruparib 200 Tablet:
Coadministration of Ruparib 200 Tablet and Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ruparib 200 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RucaparibSotalol
Severe
How does the drug interact with Ruparib 200 Tablet:
Using sotalol together with Ruparib 200 Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Ruparib 200 Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
RucaparibInfliximab
Severe
How does the drug interact with Ruparib 200 Tablet:
When Ruparib 200 Tablet is taken with Infliximab, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Ruparib 200 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibPirfenidone
Severe
How does the drug interact with Ruparib 200 Tablet:
Taking Pirfenidone with Ruparib 200 Tablet can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenidone with Ruparib 200 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
RucaparibCladribine
Severe
How does the drug interact with Ruparib 200 Tablet:
Taking Ruparib 200 Tablet with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Ruparib 200 Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
RucaparibGatifloxacin
Severe
How does the drug interact with Ruparib 200 Tablet:
Taking Gatifloxacin with Ruparib 200 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Ruparib 200 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibMoxifloxacin
Severe
How does the drug interact with Ruparib 200 Tablet:
Using moxifloxacin together with Ruparib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Ruparib 200 Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - like a fast or irregular heartbeat, severe or long-lasting diarrhea, vomiting, complications, sudden feeling dizzy or lightheaded, fainting, difficulty breathing, or feeling your heart beating fast - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain a proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Ruparib 200 Tablet Substitute

Substitutes safety advice
  • Bdparib 200 Tablet 60's

    by Others

    615.00per tablet
  • Nuparp 200 Tablet 60's

    by Others

    567.17per tablet
  • Lucaparib 200 Tablet 60's

    by Others

    630.38per tablet
  • Rucaza 200 Tablet 60's

    by Others

    533.75per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ruparib 200 Tablet works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it helps treat cancer.

Ruparib 200 Tablet may make your skin sensitive to sunlight. Therefore, avoid unnecessary or prolonged exposure to sunlight. Also, wear protective clothing and apply sunscreen.

If you experience nausea, vomiting, diarrhoea, or abdominal pain, consult your doctor, as these may be signs that Ruparib 200 Tablet is affecting your stomach or bowels.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENYTOIN
  • ROSUVASTATIN
  • CISAPRIDE
  • OMEPRAZOLE
  • CICLOSPORIN
  • SIROLIMUS
  • TACROLIMUS
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • FENTANYL
  • PIMOZIDE
  • METFORMIN
  • DIGOXIN
  • QUINIDINE
  • MIDAZOLAM
  • TIZANIDINE
  • THEOPHYLLINE

Special Advise

  • Your doctor may advise regular blood tests to check for blood cell count before treatment and every month during treatment.
  • Ruparib 200 Tablet may cause photosensitivity. So, avoid direct sunlight and do not use sunbeds. Wear protective clothing and use sunscreen.
  • Men with partners of childbearing potential must use effective contraception during treatment and for three months after the last dose. 
  • Avoid donating sperm during treatment and for three months after the last dose.
  • Women of childbearing potential must use effective contraception during treatment and for six months after the last dose. 
  • Women will need to take a pregnancy test prior to the start of the treatment.

Disease/Condition Glossary

Ovarian Cancer: Ovarian cancer begins in the female reproductive organs, where eggs are formed. Signs and symptoms include pain, swelling, or a feeling of pressure in the pelvis or abdomen; a frequent or sudden urge to urinate; feeling full or trouble eating; a lump in the pelvic area; gas, bloating, or constipation.

Fallopian tube cancer: It is the cancer that develops in the fallopian tube, the tube that transports eggs released by the ovaries to the uterus. Symptoms include lower abdominal pain, irregular vaginal bleeding or discharge, and bloating.

Peritoneal cancer: It is the cancer that develops in the thin layer of tissue that lines the abdomen. Symptoms may include a swollen abdomen, abdominal pain, bloating, nausea, vomiting, loss of appetite, constipation, or diarrhoea.

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a reproductive gland in men that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning sensations during urination.

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