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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

BUPRENORPHINE-5MCG

Manufacturer/Marketer :

Rusan Pharma Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Rupatch 5 mcg Transdermal Patch

Rupatch 5 mcg Transdermal Patch belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Rupatch 5 mcg Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonists. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Use Rupatch 5 mcg Transdermal Patch as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Rupatch 5 mcg Transdermal Patch should be avoided if you are allergic to it or any ingredients of it or opioids. Do not use Rupatch 5 mcg Transdermal Patch if you are pregnant or breastfeeding. Rupatch 5 mcg Transdermal Patch is not recommended for children below 18 years of age. Rupatch 5 mcg Transdermal Patch is a habit-forming drug; hence there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Rupatch 5 mcg Transdermal Patch may decrease fertility in men and women. Do not consume alcohol while using Rupatch 5 mcg Transdermal Patch as it may increase the risk of side effects.

Uses of Rupatch 5 mcg Transdermal Patch

Pain

Directions for Use

Transdermal Patch: Use Rupatch 5 mcg Transdermal Patch only as prescribed by a doctor. Do not use this medicine for a prolonged period.

Medicinal Benefits

The Rupatch 5 mcg Transdermal Patch contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Rupatch 5 mcg Transdermal Patch has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rupatch 5 mcg Transdermal Patch

  • Weakness
  • Anxiety
  • Nervousness
  • Dizziness
  • Headache
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Sweating
  • Application site reactions

Drug Warnings

Please do not stop using Rupatch 5 mcg Transdermal Patch suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Rupatch 5 mcg Transdermal Patch or any other medicines, please tell your doctor. Do not use Rupatch 5 mcg Transdermal Patch if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Rupatch 5 mcg Transdermal Patch is not recommended for children below 18 years of age. Avoid consuming alcohol with Rupatch 5 mcg Transdermal Patch as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Rupatch 5 mcg Transdermal Patch should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interactions

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BuprenorphineZiprasidone
Critical
BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineZiprasidone
Critical
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Taking Ziprasidone with Rupatch 5 mcg Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Rupatch 5 mcg Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineAlvimopan
Critical
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Using alvimopan together with Rupatch 5 mcg Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Rupatch 5 mcg Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
BuprenorphineCariprazine
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
When Rupatch 5 mcg Transdermal Patch is used with cariprazine, it may possibly lead to side effects.

How to manage the interaction:
Concomitant administration of Rupatch 5 mcg Transdermal Patch alongside cariprazine can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop any medication without consulting a doctor. Do not discontinue any medications without consulting your doctor.
BuprenorphineSelegiline
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
When Rupatch 5 mcg Transdermal Patch is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There's an interaction between Rupatch 5 mcg Transdermal Patch alongside Selegiline that can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
BuprenorphineEscitalopram
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Taking Rupatch 5 mcg Transdermal Patch with escitalopram increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Rupatch 5 mcg Transdermal Patch and escitalopram can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
BuprenorphinePhenobarbital
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Using phenobarbital along with Rupatch 5 mcg Transdermal Patch may lead to significant adverse effects (respiratory distress, and unconsciousness), and may drastically lower Rupatch 5 mcg Transdermal Patch levels in the blood, making the medicine less effective in treating disease.

How to manage the interaction:
Although taking phenobarbital and Rupatch 5 mcg Transdermal Patch together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary shaking and kicking, abdominal pain, decreased hunger, nausea, vomiting, diarrhea, and weight loss, consult the doctor Do not stop using any medications without talking to a doctor.
BuprenorphineFlurazepam
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
When Rupatch 5 mcg Transdermal Patch is used with flurazepam, it may lead to significant adverse effects (respiratory difficulties, unconsciousness).

How to manage the interaction:
Concomitant administration of Rupatch 5 mcg Transdermal Patch alongside flurazepam can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
BuprenorphineGabapentin
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Co-administration of Rupatch 5 mcg Transdermal Patch and Gabapentin may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Rupatch 5 mcg Transdermal Patch, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
BuprenorphineAlprazolam
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
Using Alprazolam together with Rupatch 5 mcg Transdermal Patch can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Alprazolam and Rupatch 5 mcg Transdermal Patch may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.
BuprenorphinePentazocine
Severe
How does the drug interact with Rupatch 5 mcg Transdermal Patch:
When Rupatch 5 mcg Transdermal Patch is used with pentazocine, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Rupatch 5 mcg Transdermal Patch alongside pentazocine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • Drink plenty of water during treatment with Rupatch 5 mcg Transdermal Patch to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Rupatch 5 mcg Transdermal Patch.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS

Rupatch 5 mcg Transdermal Patch Substitute

Substitutes safety advice
  • Bue-Touch 5 mcg/hr Transdermal Patch 2's

    by Others

    260.00per tablet
  • Mutrans 5mcg/Hr Transdermal Patch 2's

    by Others

    294.30per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rupatch 5 mcg Transdermal Patch consists of Buprenorphine is an opioid partial agonist. It provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

No, you are not recommended to take Rupatch 5 mcg Transdermal Patch with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Rupatch 5 mcg Transdermal Patch may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Rupatch 5 mcg Transdermal Patch with other medicines.

Yes, Rupatch 5 mcg Transdermal Patch may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while using Rupatch 5 mcg Transdermal Patch, do not stop using it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Yes, Rupatch 5 mcg Transdermal Patch may cause addiction, especially if taken for a prolonged time. Therefore, Rupatch 5 mcg Transdermal Patch should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Rupatch 5 mcg Transdermal Patch only as advised by a doctor, as overuse or misuse of Rupatch 5 mcg Transdermal Patch can lead to overdose or death.

Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • METHADONE
  • FLUOXETINE
  • DIAZEPAM
  • CODEINE
  • MORPHINE
  • AMITRIPTYLINE
  • PROMETHAZINE
  • VENLAFAXINE

Special Advise

  • Do not use Rupatch 5 mcg Transdermal Patch for a prolonged time, as it may lead to mental or physical dependence on Rupatch 5 mcg Transdermal Patch.
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Rupatch 5 mcg Transdermal Patch causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Rupatch 5 mcg Transdermal Patch can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Disease/Condition Glossary

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused due to pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.

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