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  3. Rybelsus 14 mg Tablet 10's

Rybelsus 14 mg Tablet 10's, Pack of 10 TABLETS
Rybelsus 14 mg Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

SEMAGLUTIDE-14MG

Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rybelsus 14 mg Tablet

Rybelsus 14 mg Tablet belongs to the class of medications called 'anti-diabetic agents' used to improve glycaemic control in adult patients with type 2 diabetes mellitus when diet and exercise are not enough or when the other medicines are not enough to control your blood sugar levels. Type 2 diabetes is a condition in which your body does not produce enough insulin, and the insulin produced does not drop your blood sugar as effectively as it could.

Rybelsus 14 mg Tablet comprises semaglutide. Semaglutide is a GLP-1 physiological hormone that promotes glycemic control via several mechanisms, including insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion. Changes to diet and exercise are often combined with this medication.

Take Rybelsus 14 mg Tablet as prescribed. You are advised to take Rybelsus 14 mg Tablet for as long as your doctor has advised. In some cases, Rybelsus 14 mg Tablet may cause diabetic eye disease (retinopathy), feeling sick (nausea) or being sick (vomiting), diarrhoea, low blood sugar (hypoglycaemia), upset stomach or indigestion and inflamed stomach ('gastritis'). Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, consult your doctor.

It is recommended not to take Rybelsus 14 mg Tablet if you are allergic to any of its components. You should inform your doctor if you get eye problems. If you have significant and ongoing stomach pain, consult a doctor immediately, as this could be a sign of an inflamed pancreas (acute pancreatitis). Avoiding alcohol is recommended to rule out any risk of lactic acidosis or other complications. Rybelsus 14 mg Tablet is not recommended to use in a pregnant woman or nursing mother, or children below 18 years of age. If you become pregnant while using this medication, contact your doctor immediately since your treatment will need to be modified. Caution should be exercised. If your blood sugar is too low or too high, your driving ability may be affected. Do not drive if these symptoms appear.

Uses of Rybelsus 14 mg Tablet

Type 2 Diabetes Mellitus

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rybelsus 14 mg Tablet is used to treat type 2 diabetes in people 18 years and older. It is used when diet and exercise are not enough on their own or cannot use another diabetes medicine or when the other drugs are not enough to control or maintain your blood sugar levels. Rybelsus 14 mg Tablet comprises semaglutide. Semaglutide is a GLP-1 physiological hormone that promotes glycemic control via several mechanisms, including insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion. Changes to diet and exercise are often combined with this medication.

Storage

Store in a cool and dry place away from sunlight
Side effects of Rybelsus 14 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

It is recommended not to take Rybelsus 14 mg Tablet if you are allergic to any of its components. You should inform your doctor if you get eye problems, such as changes in vision, during treatment with this medicine as the Rybelsus 14 mg Tablet may lead to complications of diabetic eye disease (retinopathy). When taking this medication, you may feel nauseous (nausea), sick (vomiting), or have diarrhoea. These adverse effects may result in dehydration (loss of fluids). You must consume enough water to avoid dehydration, especially if you have kidney issues. If you have any questions or concerns, consult your doctor. If you have significant and ongoing stomach pain, consult a doctor immediately, as this could be a sign of an inflamed pancreas (acute pancreatitis). Avoiding alcohol is recommended to rule out any risk of lactic acidosis or other complications. Rybelsus 14 mg Tablet is not recommended for pregnant women, nursing mothers, or people below 18 years of age. If you become pregnant while taking this medication, contact your doctor immediately since your treatment will need to be modified.

Drug-Drug Interactions

verifiedApollotooltip
SemaglutideGatifloxacin
Critical
SemaglutideBexarotene
Severe

Drug-Drug Interactions

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SemaglutideGatifloxacin
Critical
How does the drug interact with Rybelsus 14 mg Tablet:
Coadministration of Rybelsus 14 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Rybelsus 14 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the doctor if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without first consulting your doctor.
SemaglutideBexarotene
Severe
How does the drug interact with Rybelsus 14 mg Tablet:
Co-administration of Bexarotene and Rybelsus 14 mg Tablet can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Bexarotene and Rybelsus 14 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SemaglutideTirzepatide
Moderate
How does the drug interact with Rybelsus 14 mg Tablet:
As tirzepatide and Rybelsus 14 mg Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat at regular intervals. Do not take a long gap between meals or snacks.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrate-containing foods with whole-grain foods. Increase fruits, vegetables and other fibre-enriched foods in your diet.
  • Reduce saturated fat foods such as chips, crisps, pastries, biscuits, and samosas.
  • Choose omega-3 fatty acid-containing oils for daily cooking. 
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Avoid drinking alcohol while on Rybelsus 14 mg Tablet . It increases the risk of hypoglycaemia (a decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts various organs).
  • Try to quit smoking and reduce your intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar, etc.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:46 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rybelsus 14 mg Tablet contains semaglutide. Semaglutide is a GLP-1 hormone that enhances glycemic control through various mechanisms, including insulin secretion, slowing gastric emptying, and decreasing postprandial glucagon secretion. This drug is frequently paired with dietary and exercise changes. Altogether Rybelsus 14 mg Tablet reduces sugar levels in the body.

Low blood glucose levels are referred to as hypoglycaemia. Rybelsus 14 mg Tablet may result in hypoglycaemia. Hypoglycaemia can occur if you skip or delay eating, drink alcohol, exercise strenuously, or take other diabetes medications in addition to Rybelsus 14 mg Tablet .

Do not stop taking Rybelsus 14 mg Tablet without first consulting your doctor. Take Rybelsus 14 mg Tablet for as long as the doctor has instructed. Consult a doctor if you have any problems while taking Rybelsus 14 mg Tablet .

Take the missed dose as soon as you remember. If it is time for the next scheduled dose, skip the missing dose and resume your regular dosing regimen. Do not double the dose.

Caution should be exercised if you have severe and ongoing pain in the stomach area. It is recommended to consult a doctor immediately, as this could signify an inflamed pancreas (acute pancreatitis). Your doctor will weigh the benefits and potential risks before prescribing this medication.

Rybelsus 14 mg Tablet is not recommended to treat type 1 diabetes (your body produces no insulin).

Rybelsus 14 mg Tablet should not use if you have type 1 diabetes or diabetic ketoacidosis or if you are allergic to Semaglutide or any of the other ingredients of this medicine.

Drug-Drug Interactions Checker List

  • LEVOTHYROXINE
  • WARFARIN
  • BEXAROTENE
  • GATIFLOXACIN
  • INSULIN

Special Advise

  • Keep taking Rybelsus 14 mg Tablet even if your blood sugar levels are controlled until the doctor advises you to stop it.
  • Recommend you monitor your blood sugar frequently.
  • Monitoring of pancreatic enzymes (such as lipase and amylase) is recommended.
  • Take short, frequent meals, and avoid prolonged fasting when taking Rybelsus 14 mg Tablet . Beware of hypoglycaemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.

Disease/Condition Glossary

Type 2 diabetes: Type 2 diabetes is a medical condition in which your body does not produce enough insulin, and the insulin produced does not drop your blood sugar as effectively as it could. In some situations, your body may produce excessive blood sugar. If your blood sugar rises and stays high for an extended amount of time, it can cause problems such as heart disease, renal disease, eye abnormalities, and poor circulation in your limbs. Therefore it is critical to maintain your blood sugar levels balanced.

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