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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:17 PM IST

About Ryverna 10Mg/ ml Inj 10 ml

Ryverna 10Mg/ ml Inj 10 ml belongs to the group of medicines called monoclonal antibodies, which is indicated to reduce the frequency of vaso-occlusive crises (VOCs) in adults and pediatric patients aged 16 years and older with sickle cell disease. A vaso-occlusive crisis, or VOC, occurs when sickled red blood cells obstruct blood flow to the point where tissues are deprived of oxygen. This, in turn, causes an inflammatory reaction. The outcome is severe pain, which can affect any part of the body but is most typically felt in the back, chest, or extremities.

Ryverna 10Mg/ ml Inj 10 ml contains Crizanlizumab-tmca, which works by blocking certain blood cells from interacting.

Ryverna 10Mg/ ml Inj 10 ml will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on your medical condition. In some cases, Ryverna 10Mg/ ml Inj 10 ml may cause Infusion site reactions, nausea, arthralgia (pain in a joint), back pain, and pyrexia (fever). Most of these side effects do not require medical treatment and fade away with time. However, consult your doctor if the side effects persist or worsen.

Before taking the Ryverna 10Mg/ ml Inj 10 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Ryverna 10Mg/ ml Inj 10 ml may cause fetal harm. So, inform your doctor if you are pregnant and planning to become pregnant. Do not breastfeed while on medication unless recommended by the doctor. Ryverna 10Mg/ ml Inj 10 ml is not recommended for children below 16 years as the safety and effectiveness have not been established. Consumption of alcohol is not recommended while on therapy.

Uses of Ryverna 10Mg/ ml Inj 10 ml

Vaso-Occlusive Crises (VOCs)

Medicinal Benefits

Ryverna 10Mg/ ml Inj 10 ml contains Crizanlizumab-tmca, which belongs to the group of medicines called monoclonal antibodies and is indicated to reduce the frequency of vaso-occlusive crises (VOCs) in adults and pediatric patients aged 16 years and older with sickle cell disease. Crizanlizumab-tmca which works by binding to the protein P-selectin in the blood. This protein is responsible for the adhesion of blood cells. By inhibiting P-selectin, blood cell limitations are avoided, and blood supply throughout the body is improved.

Directions for Use

Ryverna 10Mg/ ml Inj 10 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ryverna 10Mg/ ml Inj 10 ml

  • Infusion site reactions
  • Nausea
  • Arthralgia (pain in a joint)
  • Back pain
  • Pyrexia (fever)

Drug Warnings

Before using the Ryverna 10Mg/ ml Inj 10 ml, inform your doctor about your medical conditions (e.g., pregnancy, nursing, any scheduled surgery, etc.), sensitivities (allergic reactions to foods and medicines), and medications you are taking. Other drugs (especially corticosteroids) or supplements should not be taken with Ryverna 10Mg/ ml Inj 10 ml unless prescribed by a doctor. Do not miss any doses and finish the entire course of medicine. Stopping the drug too soon may cause the infection to reoccur or worsen.

Drug Interactions

Drug-Drug Interactions: Ryverna 10Mg/ ml Inj 10 ml may interact with a medication used to treat a certain form of myasthenia gravis (Efgartigimod alfa, Rozanolixizumab) and corticosteroid medications.

Drug-Food Interactions: Avoid the consumption of alcohol while taking Ryverna 10Mg/ ml Inj 10 ml.

Drug-Disease Interactions: Caution is advised if used Ryverna 10Mg/ ml Inj 10 ml in patients with renal or hepatic impairment.

Drug-Drug Interactions Checker List

  • EFGARTIGIMOD ALFA
  • ROZANOLIXIZUMAB

Habit Forming

No

Diet & Lifestyle Advise

  • A healthy diet is good for everyone, but it's especially crucial for those with sickle cell disease (SCD). Low levels of important nutrients such as proteins, minerals, and vitamins have been related to SCD.
  • Adopting a diet that is high in protein and other nutrients can help lessen discomfort and other SCD consequences.
  • Sickle cell disease patients should drink 8 to 10 glasses of water every day and eat nutritious foods. Try to stay cool, chilly, and energized.
  • A healthy diet high in zinc, folate, and water may assist in reducing the condition's consequences.

Special Advise

  • Platelet Counts should be evaluated on a regular basis throughout Ryverna 10Mg/ ml Inj 10 ml treatment and until full recovery is achieved.

Disease/Condition Glossary

A vaso-occlusive crisis, or VOC, occurs when sickled red blood cells obstruct blood flow to the point where tissues are deprived of oxygen. This, in turn, causes an inflammatory reaction. The outcome is severe pain, which can affect any body part but is most typically felt in the back, chest, or extremities.

About Ryverna 10Mg/ ml Inj 10 ml

Ryverna 10Mg/ ml Inj 10 ml belongs to the group of medicines called monoclonal antibodies, which is indicated to reduce the frequency of vaso-occlusive crises (VOCs) in adults and pediatric patients aged 16 years and older with sickle cell disease. A vaso-occlusive crisis, or VOC, occurs when sickled red blood cells obstruct blood flow to the point where tissues are deprived of oxygen. This, in turn, causes an inflammatory reaction. The outcome is severe pain, which can affect any part of the body but is most typically felt in the back, chest, or extremities.

Ryverna 10Mg/ ml Inj 10 ml contains Crizanlizumab-tmca, which works by blocking certain blood cells from interacting.

Ryverna 10Mg/ ml Inj 10 ml will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on your medical condition. In some cases, Ryverna 10Mg/ ml Inj 10 ml may cause Infusion site reactions, nausea, arthralgia (pain in a joint), back pain, and pyrexia (fever). Most of these side effects do not require medical treatment and fade away with time. However, consult your doctor if the side effects persist or worsen.

Before taking the Ryverna 10Mg/ ml Inj 10 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Ryverna 10Mg/ ml Inj 10 ml may cause fetal harm. So, inform your doctor if you are pregnant and planning to become pregnant. Do not breastfeed while on medication unless recommended by the doctor. Ryverna 10Mg/ ml Inj 10 ml is not recommended for children below 16 years as the safety and effectiveness have not been established. Consumption of alcohol is not recommended while on therapy.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Ryverna 10Mg/ ml Inj 10 ml

Vaso-Occlusive Crises (VOCs)

Medicinal Benefits

Ryverna 10Mg/ ml Inj 10 ml contains Crizanlizumab-tmca, which belongs to the group of medicines called monoclonal antibodies and is indicated to reduce the frequency of vaso-occlusive crises (VOCs) in adults and pediatric patients aged 16 years and older with sickle cell disease. Crizanlizumab-tmca which works by binding to the protein P-selectin in the blood. This protein is responsible for the adhesion of blood cells. By inhibiting P-selectin, blood cell limitations are avoided, and blood supply throughout the body is improved.

Side Effects of Ryverna 10Mg/ ml Inj 10 ml

  • Infusion site reactions
  • Nausea
  • Arthralgia (pain in a joint)
  • Back pain
  • Pyrexia (fever)

Directions for Use

Ryverna 10Mg/ ml Inj 10 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before using the Ryverna 10Mg/ ml Inj 10 ml, inform your doctor about your medical conditions (e.g., pregnancy, nursing, any scheduled surgery, etc.), sensitivities (allergic reactions to foods and medicines), and medications you are taking. Other drugs (especially corticosteroids) or supplements should not be taken with Ryverna 10Mg/ ml Inj 10 ml unless prescribed by a doctor. Do not miss any doses and finish the entire course of medicine. Stopping the drug too soon may cause the infection to reoccur or worsen.

Therapeutic Class

MONOCLONAL ANTIBODIES

Drug-Drug Interactions Checker List

  • EFGARTIGIMOD ALFA
  • ROZANOLIXIZUMAB

Diet & Lifestyle Advise

  • A healthy diet is good for everyone, but it's especially crucial for those with sickle cell disease (SCD). Low levels of important nutrients such as proteins, minerals, and vitamins have been related to SCD.
  • Adopting a diet that is high in protein and other nutrients can help lessen discomfort and other SCD consequences.
  • Sickle cell disease patients should drink 8 to 10 glasses of water every day and eat nutritious foods. Try to stay cool, chilly, and energized.
  • A healthy diet high in zinc, folate, and water may assist in reducing the condition's consequences.

Habit Forming

No

Special Advise

  • Platelet Counts should be evaluated on a regular basis throughout Ryverna 10Mg/ ml Inj 10 ml treatment and until full recovery is achieved.

Disease/Condition Glossary

A vaso-occlusive crisis, or VOC, occurs when sickled red blood cells obstruct blood flow to the point where tissues are deprived of oxygen. This, in turn, causes an inflammatory reaction. The outcome is severe pain, which can affect any body part but is most typically felt in the back, chest, or extremities.