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Written By ,
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About SAFEGUAR DSR TABLET

SAFEGUAR DSR TABLET belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

SAFEGUAR DSR TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Take SAFEGUAR DSR TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take SAFEGUAR DSR TABLET for as long as your doctor has prescribed it for you. You may experience diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of SAFEGUAR DSR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using the SAFEGUAR DSR TABLET, tell your doctor if you have had a heart attack or stroke, stomach or bowel disorder, liver disease, porphyria ( inherited blood disorder), asthma, high blood pressure, diabetes, and stomach or intestinal bleeding. Do not take SAFEGUAR DSR TABLET if you are a pregnant or breastfeeding woman. Consumption of alcohol should be avoided during the treatment with SAFEGUAR DSR TABLET as it may lead to an increased risk of liver damage. SAFEGUAR DSR TABLET is not recommended for use in children. Limit alcoholic beverages while on this medication.

Uses of SAFEGUAR DSR TABLET

Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

SAFEGUAR DSR TABLET is used to treat aches and pains and musculoskeletal and joint pain problems due to arthritis. SAFEGUAR DSR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Storage

Keep SAFEGUAR DSR TABLET out of the sight and reach of children.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with SAFEGUAR DSR TABLET. Patients with stomach ulcers, gastric bleeding, heart failure, and high blood pressure should not take SAFEGUAR DSR TABLET. If pregnant or breastfeeding, do not take SAFEGUAR DSR TABLET without talking with the doctor. SAFEGUAR DSR TABLET is not recommended for children below 18 years old. Seek medical help immediately if you have signs of a heart attack or stroke. Stop using SAFEGUAR DSR TABLET and call your doctor immediately if you notice heart problems, kidney problems, liver problems, or stomach bleeding signs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Safeguar Dsr Tablet:
Co-administration of Safeguar Dsr Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Safeguar Dsr Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Safeguar Dsr Tablet:
Combined use of Safeguar Dsr Tablet and Dinoprostone can affect the metabolism of Safeguar Dsr Tablet.

How to manage the interaction:
Taking Safeguar Dsr Tablet and Dinoprostone together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Safeguar Dsr Tablet:
Coadministration of Safeguar Dsr Tablet and Oxytocin can enhance the action of oxytocin. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Safeguar Dsr Tablet and Oxytocin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden or severe stomach pain, unexplained vaginal bleeding, Fast heart rate or low blood pressure in the pregnant person, diarrhea, or dehydration, consult to a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Safeguar Dsr Tablet:
Taking Safeguar Dsr Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Safeguar Dsr Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Safeguar Dsr Tablet:
Co-administration of methotrexate with Safeguar Dsr Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Safeguar Dsr Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Safeguar Dsr Tablet:
Co-administration of Safeguar Dsr Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Safeguar Dsr Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Safeguar Dsr Tablet:
Concomitant use of Safeguar Dsr Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Safeguar Dsr Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Safeguar Dsr Tablet:
Coadministration of Safeguar Dsr Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Safeguar Dsr Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with Safeguar Dsr Tablet:
Taking Valdecoxib with Safeguar Dsr Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Safeguar Dsr Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
How does the drug interact with Safeguar Dsr Tablet:
Co-administration of Safeguar Dsr Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Safeguar Dsr Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Side Effects of SAFEGUAR DSR TABLET

  • Diarrhea
  • Stomach/abdominal pain
  • Nausea
  • Heartburn
  • Difficulty sleeping
  • Ulcers in the stomach or intestines
  • Drowsiness
  • Dizziness
  • Indigestion

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

SAFEGUAR DSR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. Thereby, SAFEGUAR DSR TABLET helps in relieving pain and swelling associated with different types of arthritis.

No, SAFEGUAR DSR TABLET is not a narcotic pain killer. It belongs to the non-steroidal anti-inflammatory drugs (NSAIDs) group of medications.

Yes, SAFEGUAR DSR TABLET can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.

SAFEGUAR DSR TABLET may increase the risk of heart problems such as heart attack, especially when used in high doses or for a prolonged duration, and in patients who are smokers, have high blood pressure, diabetes, or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking SAFEGUAR DSR TABLET. However, it is recommended to take SAFEGUAR DSR TABLET in the dose and for the duration as prescribed by your doctor.

SAFEGUAR DSR TABLET is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.

No, SAFEGUAR DSR TABLET does not cure arthritis. SAFEGUAR DSR TABLET is only used to relieve symptoms of arthritis such as joint pain, swelling, and stiffness.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • INDOMETHACIN
  • MELOXICAM
  • WARFARIN
  • HYDROCHLOROTHIAZIDE
  • LITHIUM

Special Advise

 

Disease/Condition Glossary

Osteoarthritis: Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age. The older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, dislocated joints, and ligaments.

Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms include pain, swelling, stiffness, deformities, and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other parts of the body. Ankylosing spondylitis includes decreased flexibility, which usually leads to hunched-forward posture, pain, and back and joints.

Have a query?

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Alcohol

Unsafe

Do not consume alcohol along with SAFEGUAR DSR TABLET as it can cause unpleasant side-effects like gastric bleeding.

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Pregnancy

Unsafe

Please consult your doctor if you are pregnant; your doctor will prescribe SAFEGUAR DSR TABLET only if the benefits outweigh the risks. Taking SAFEGUAR DSR TABLET in the last 20 weeks of pregnancy may cause serious kidney or heart problems in the unborn baby.

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Breast Feeding

Caution

While SAFEGUAR DSR TABLET may pass in the lactating mother's breast milk, So, do it is advisable to take it only if prescribed by your doctor.

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Driving

Caution

SAFEGUAR DSR TABLET may cause dizziness and drowsiness. So, if you observe such symptoms, do not drive.

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Liver

Caution

Limited information was available for the use of SAFEGUAR DSR TABLET in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using SAFEGUAR DSR TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of SAFEGUAR DSR TABLET in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using SAFEGUAR DSR TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

SAFEGUAR DSR TABLET not recommended for children under 18 years of age.

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