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  3. Safenix 100mg/5ml Dry Syrup

Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Synonym :

CEFPODOXIME

Manufacturer/Marketer :

Canixa Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Safenix 100mg/5ml Dry Syrup

Safenix 100mg/5ml Dry Syrup belongs to the group of antibiotic medicines called 'cephalosporins' used to treat bacterial infections of the ear, nose, throat, lower respiratory tract, urinary tract, skin, and soft tissue in children. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.

Safenix 100mg/5ml Dry Syrup contains 'Cefpodoxime Proxetil', a broad-spectrum antibiotic effective against both gram-positive and negative groups of bacteria. It works by preventing the formation of bacterial cell covering (cell wall), which is necessary for their survival. Thereby, it kills the bacteria and helps treat and prevent bacterial infection spread.

Like all medicines, Safenix 100mg/5ml Dry Syrup may cause some common side effects, including nausea, vomiting, diarrhoea (watery or loose stool), abdominal pain, loss of appetite, bloating, skin rash, and itching. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child's condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Safenix 100mg/5ml Dry Syrup unless prescribed by a doctor. Even if your child is feeling better after taking a few doses, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Safenix 100mg/5ml Dry Syrup

Bacterial infections.

Directions for Use

Dry syrup for oral suspension: Check the label for directions before use. Mix the content in the less amount of water provided with the pack, and add the remaining water to make the volume up to the mark on the container. Mix well and administer to your child as directed by the physician.

Medicinal Benefits

Safenix 100mg/5ml Dry Syrup belongs to the group of antibiotic medicines called 'cephalosporins' used to treat a wide range of ear, nose, throat, lower respiratory tract, urinary tract, skin, and soft tissue bacterial infections. It is composed of Cefpodoxime Proxetil. It is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria. Safenix 100mg/5ml Dry Syrup works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, it kills the bacteria and helps treat and prevent the spread of infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Safenix 100mg/5ml Dry Syrup
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Inform your doctor if you suspect a fungal skin infection for proper diagnosis and treatment.
  • Wash the affected area with mild soap and water to prevent spreading.
  • Avoid sharing personal items like towels, clothing, or makeup to prevent spreading.
  • Wash your hands regularly, especially after touching the affected area.
  • Avoid scratching, as it can worsen or spread the infection. Keep the area covered to prevent itching.
  • If your symptoms worsen or don't get better, seek professional help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Before using Safenix 100mg/5ml Dry Syrup, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Safenix 100mg/5ml Dry Syrup unless prescribed by the doctor. Give the medicine exactly as directed. Please do not use one child's antibiotic for others; it may cause harm.

Drug-Drug Interactions

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CefpodoximeCholera, live attenuated
Severe

Drug-Drug Interactions

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How does the drug interact with Safenix 100mg/5ml Dry Syrup:
Co-administration of Safenix 100mg/5ml Dry Syrup with Heparin may enhance the levels or effects of heparin by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Safenix 100mg/5ml Dry Syrup can be taken with Heparin if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CefpodoximeCholera, live attenuated
Severe
How does the drug interact with Safenix 100mg/5ml Dry Syrup:
Co-administration of Safenix 100mg/5ml Dry Syrup with the Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Safenix 100mg/5ml Dry Syrup or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Safenix 100mg/5ml Dry Syrup to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • The BRAT diet (bananas, rice, applesauce, toast) can help treat diarrhoea caused due to antibiotic use.

  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.

  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.

  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Safenix 100mg/5ml Dry Syrup.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Drug-Diseases Interactions

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CEFPODOXIME PROXETIL-100MG/5MLOther bacterial intestinal infections
Severe
CEFPODOXIME PROXETIL-100MG/5MLDisorders resulting from impaired renal tubular function
Moderate

Drug-Diseases Interactions

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CEFPODOXIME PROXETIL-100MG/5MLOther bacterial intestinal infections
Severe
How does the disease interact with Safenix 100mg/5ml Dry Syrup:
Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFPODOXIME PROXETIL-100MG/5MLDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Safenix 100mg/5ml Dry Syrup:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
CEFPODOXIME PROXETIL-100MG/5MLAbnormal serum enzyme levels
Moderate
How does the disease interact with Safenix 100mg/5ml Dry Syrup:
Certain cephalosporins have been associated with cases of hepatitis. There has also been a brief increase in the levels of AST, ALT, and alkaline phosphatase. Patients with hepatic problems should be treated with caution and under close observation when using these medications.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
CEFPODOXIME PROXETIL-100MG/5MLEpilepsy
Moderate
How does the disease interact with Safenix 100mg/5ml Dry Syrup:
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.

FAQs

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • WARFARIN
  • CALCIUM
  • VITAMIN D
  • CIMETIDINE
  • RANITIDINE
  • PROBENECID

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

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