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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Sampill AT 2.5mg/50mg Tablet

Sampill AT 2.5mg/50mg Tablet belongs to a class of 'anti-hypertensive' medication primarily used to treat hypertension (high blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the blood pressure against the artery walls becomes too high. This can lead to damaged blood vessels, heart disease, stroke, kidney disease, and other problems.

Sampill AT 2.5mg/50mg Tablet contains Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker). Amlodipine acts by relaxing and widening the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by blocking stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower raised blood pressure, reducing the chances of heart attack or stroke in the future.

Take Sampill AT 2.5mg/50mg Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Sampill AT 2.5mg/50mg Tablet for as long as your doctor has prescribed it for you. The most common side effects of Sampill AT 2.5mg/50mg Tablet are nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, tiredness. They do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Sampill AT 2.5mg/50mg Tablet, are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, a heart valve problem or a history of a heart attack. It is recommended to monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor. It is advisable to drink plenty of fluids while taking this medicine. However, kidney patients should avoid taking plenty of fluids.

Uses of Sampill AT 2.5mg/50mg Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Sampill AT 2.5mg/50mg Tablet is a combination drug containing 'anti-hypertensive' drugs containing Amlodipine (a calcium channel blocker) and Atenolol (a beta-blocker) primarily taken for the treatment of hypertension (high blood pressure). Sampill AT 2.5mg/50mg Tablet reduces the heart's workload making the heart more efficient at pumping blood throughout the body and relaxing and widening the blood vessel. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sampill AT 2.5mg/50mg Tablet

  • Nausea
  • Sleepiness
  • Ankle swelling
  • Headache 
  • Palpitations
  • Cold extremities
  • Flushing (sense of warmth in the face, ears, neck, and trunk)
  • Slow heart rate
  • Oedema (swelling) 
  • Constipation
  • Tiredness

Drug Warnings

Inform your doctor if you have had an allergic reaction to Sampill AT 2.5mg/50mg Tablet, are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, a heart valve problem, or have a history of a heart attack. And also disclose to your doctor all the prescription and over-the-counter medications you use, including vitamins, minerals, herbal products, and drugs other prescribed medications. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. Do not start using a new medication without telling your doctor. And also, keep your doctor informed if you are taking anti-diabetic medicines along with Sampill AT 2.5mg/50mg Tablet. Sampill AT 2.5mg/50mg Tablet contains Atenolol, a category D pregnancy drug, so it should not be taken if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the baby. Lifestyle changes are beneficial in achieving optimum outcomes with Sampill AT 2.5mg/50mg Tablet and keeping blood pressure under check. A low salt diet, daily physical activity, losing weight in the case of people who are obese, etc., are the mainstay of the treatment of hypertension.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AtenololTizanidine
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Using Sampill AT 2.5mg/50mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AtenololTizanidine
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Coadministration of Tizanidine and Sampill AT 2.5mg/50mg Tablet can increase the risk or severity of side effects like low blood pressure.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and tizanidine together may result in an interaction, it can be taken if your doctor has recommended it. However, if you experience headache, dizziness, lightheadedness, sweating, or palpitations, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtenololDiltiazem
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Taking Sampill AT 2.5mg/50mg Tablet and diltiazem together may lead to increased side effects.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and diltiazem together can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience tiredness, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest discomfort, increased or reduced heartbeat, or irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting doctor.
AtenololTheophylline
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Using Sampill AT 2.5mg/50mg Tablet with theophylline, could increase the effects of theophylline.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and theophylline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
AtenololAtazanavir
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
The use of atazanavir with Sampill AT 2.5mg/50mg Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
The combination of Sampill AT 2.5mg/50mg Tablet and acebutolol may result in an interaction, it can be taken if a doctor has advised it. However, if you develop sudden dizziness, lightheadedness, fainting, or irregular heartbeat, contact the doctor immediately. Do not stop using any medications without a doctor's advice.
AtenololRitodrine
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Coadministration of Sampill AT 2.5mg/50mg Tablet and ritodrine may cause either medication to be less effective.

How to manage the interaction:
Although taking Sampill AT 2.5mg/50mg Tablet with ritodrine can result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
AtenololCeritinib
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Coadministration of Sampill AT 2.5mg/50mg Tablet with ceritinib can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and ceritinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, or an irregular heartbeat while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
AtenololCarvedilol
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Taking Sampill AT 2.5mg/50mg Tablet and carvedilol may increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and Carvedilol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any shortness of breath, palpitations, or chest discomfort, contact a doctor immediately. Do not stop taking any medication without checking with a doctor.
AtenololAcebutolol
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Coadministration of Sampill AT 2.5mg/50mg Tablet and Acebutolol they both may enhance blood pressure-lowering effect.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and acebutolol together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AtenololVerapamil
Severe
How does the drug interact with Sampill AT 2.5mg/50mg Tablet:
Taking verapamil with Sampill AT 2.5mg/50mg Tablet can increase the risk or severity of verapamil side effects.

How to manage the interaction:
Taking Sampill AT 2.5mg/50mg Tablet and Verapamil together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience, fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-2.5MG+ATENOLOL-50MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-2.5MG+ATENOLOL-50MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice while being treated with Sampill AT 2.5mg/50mg Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Sampill AT 2.5mg/50mg Tablet Substitute

Substitutes safety advice
  • SAMLOKIND AT TABLET

    by Others

    3.92per tablet
  • Esamlo-AT Tablet 10's

    by Others

    12.33per tablet
  • Amten-AT Tablet 10's

    by Others

    8.20per tablet
  • Alis AT 2.5mg/50mg Tablet

    by Others

    4.05per tablet
  • Esdil AT 2.5mg/50mg Tablet

    by Others

    3.23per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sampill AT 2.5mg/50mg Tablet is a combination of anti-hypertensive medications. Amlodipine acts by relaxing and widening the constricted blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Atenolol works by slowing down the heart rate of the heart. Thus, it collectively helps lower high blood pressure, reducing the chances of heart attack or stroke.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it. If you suddenly stop taking Sampill AT 2.5mg/50mg Tablet, it may cause a jump in blood pressure, chest pain, or can even lead to a heart attack.

Yes, Sampill AT 2.5mg/50mg Tablet is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and during delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.

It is also known as fluid retention or fluid overload. Due to oedema, the affected area starts swelling up. If it does not subside, please consult your doctor immediately.

Yes, Sampill AT 2.5mg/50mg Tablet can cause dizziness sometimes, so it is advised to avoid driving or operating heavy machinery while taking Sampill AT 2.5mg/50mg Tablet. In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

Yes, Sampill AT 2.5mg/50mg Tablet is contraindicated in people with known allergies to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided for use in pregnant women who are in the second and third trimesters of their pregnancy.

The effect of this medicine can be observed within 2 to 4 hours.

Drug-Drug Interactions Checker List

  • AMILORIDE
  • EPHEDRINE
  • SPIRONOLACTONE
  • LITHIUM
  • BENAZEPRIL
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SIMVASTATIN
  • SILDENAFIL
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • RIFAMPICIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CYCLOSPORINE
  • TACROLIMUS
  • IBUPROFEN
  • ASPIRIN

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

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