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  3. Scleteri 14 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

TERIFLUNOMIDE-14MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Scleteri 14mg Tablet

Scleteri 14mg Tablet belongs to the class of medicines called immunomodulatory agents indicated in the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Multiple sclerosis is a condition in which nerves do not function properly.
 
Scleteri 14mg Tablet contains Teriflunomide, which works by decreasing inflammation and the action of immune cells that cause nerve damage. Thus, it helps treat multiple sclerosis.
 
In some cases, Scleteri 14mg Tablet may cause side effects such as headache, nausea, diarrhoea, and hair loss. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.
 
Do not take Scleteri 14mg Tablet if you are pregnant or breastfeeding. Scleteri 14mg Tablet is not recommended for children as safety and effectiveness have not been established. Inform the doctor about the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Scleteri 14mg Tablet

Multiple sclerosis

Directions for Use

Take the medicine as advised by the doctor. Treatment will be overseen by a doctor who is experienced in the treatment of multiple sclerosis.

Medicinal Benefits

Scleteri 14mg Tablet belongs to the class of medicines called immunomodulatory agents indicated in the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Scleteri 14mg Tablet contains Teriflunomide, which works by protecting the central nervous system against attacks by the immune system by limiting the increase of lymphocytes (white blood cells). This helps limit the inflammation that leads to nerve damage in multiple sclerosis.

Storage

Keep Scleteri 14mg Tablet out of reach and sight of children.
Side effects of Scleteri 14 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

Drug Warnings

Do not take Scleteri 14mg Tablet if you are allergic to any of its components, teriflunomide or leflunomide; if you have severe liver disease, any serious condition that affects the immune system, bone marrow problems, low blood count, serious infection, serious kidney problem which requires dialysis, or hypoproteinaemia (low levels of protein). Inform the doctor if you have liver problems, high blood pressure, infection, diabetes, breathing problems, severe skin reactions, respiratory symptoms, tuberculosis, or peripheral neuropathy. Do not take Scleteri 14mg Tablet if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Scleteri 14mg Tablet . This medicine may cause serious or life-threatening liver damage that may require a liver transplant. The risk of liver damage may be increased in people taking other medications known to cause liver damage and in people who already have liver disease. Seek medical attention if you experience symptoms of liver problems such as nausea, vomiting, unusual bleeding or bruising, extreme tiredness, lack of energy, pain in the upper right part of the stomach, loss of appetite, yellowing of the skin or eyes, dark-coloured urine, or flu-like symptoms. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Scleteri 14 mg Tablet:
Hydroxycarbamide when used in conjunction with Scleteri 14 mg Tablet may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Scleteri 14 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Scleteri 14 mg Tablet:
Using Mitoxantrone together with Scleteri 14 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking Mitoxantrone and Scleteri 14 mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, sore throat, muscle aches, shortness of breath, weight loss, discomfort, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Taking Scleteri 14 mg Tablet with tamoxifen may increase the risk of liver problems.

How to manage the interaction:
Although taking tamoxifen and Scleteri 14 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Co-administration of Cyclophosphamide with Scleteri 14 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Cyclophosphamide and Scleteri 14 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like fever, chills, sore throat, or muscle aches, it's best to contact a doctor right away. Other symptoms to watch out for include diarrhea, shortness of breath, weight loss, or pain during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Scleteri 14 mg Tablet can cause liver issues, and combining it with azithromycin, can raise the risk.

How to manage the interaction:
Although administration of azithromycin alongside Scleteri 14 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you notice fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Taking lenvatinib with Scleteri 14 mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Lenvatinib and Scleteri 14 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Scleteri 14 mg Tablet:
The use of asparaginase in conjunction with Scleteri 14 mg Tablet may raise the risk of severe infections, liver problems.

How to manage the interaction:
Co-administration of Asparaginase with Scleteri 14 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Co-administration of cholestyramine and Scleteri 14 mg Tablet may interfere with the effectiveness of Scleteri 14 mg Tablet.

How to manage the interaction:
Although taking cholestyramine and Scleteri 14 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Taking Ceritinib with Scleteri 14 mg Tablet may increase risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Ceritinib and Scleteri 14 mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience any symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark colored urine, liver damage, or bleeding, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Scleteri 14 mg Tablet:
Coadministration of Nevirapine and Scleteri 14 mg Tablet can increase the risk and severity of liver problems.

How to manage the interaction:
Although taking Nevirapine and Scleteri 14 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding make sure to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid heavily processed foods and saturated fats.
  • Include fruits, vegetables, and whole grains in the diet.
  • Try to stay active. Choose moderate exercises.
  • Quit smoking.
  • Prevent stress by doing meditation or yoga.

Side Effects of Scleteri 14mg Tablet

  • Headache
  • Nausea
  • Diarrhoea
  • Hair loss

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Scleteri 14mg Tablet works by decreasing inflammation and the action of immune cells that cause nerve damage.

Scleteri 14mg Tablet may cause inflammation of the pancreas. Consult the doctor if you experience nausea, vomiting or pain in the abdomen.

Avoid undergoing any vaccination while on treatment with Scleteri 14mg Tablet and for six months after taking the last dose of it. Talk to the doctor if you are due to undergo any vaccinations.

Scleteri 14mg Tablet may increase blood pressure. Your doctor may monitor blood pressure levels before and during the treatment.

Drug-Drug Interactions Checker List

  • ETHINYLESTRADIOL
  • LEVONORGESTREL
  • WARFARIN
  • ROSUVASTATIN

Special Advise

  • Avoid undergoing any vaccination while on treatment with Scleteri 14mg Tablet and for six months after you stop taking it.
  • You must not begin taking Scleteri 14mg Tablet until you have taken a pregnancy test with negative results and your doctor tells you that you are not pregnant.
  • Women should use effective contraception during treatment with Scleteri 14mg Tablet and for up to 2 years after the last dose.
  • Men with partners of reproductive potential must use reliable methods of contraception during treatment with Scleteri 14mg Tablet .
  • Regular liver function tests are advised.

Disease/Condition Glossary

Multiple sclerosis: It is an autoimmune disease (the body attacks itself by mistake) that affects the central nervous system (brain and spinal cord). The immune system damages the myelin sheath (protective covering surrounding the nerve cells), leading to disrupted communication between the brain and the body. People suffering from multiple sclerosis may experience loss of muscle coordination, numbness, weakness, and problems with bladder control, vision, and speech.

Have a query?

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Alcohol

Consult your doctor

It is unknown if Scleteri 14mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Teriflunomide belongs to pregnancy category X. Do not take Scleteri 14mg Tablet if you are pregnant, planning for pregnancy or think you may be pregnant.

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Breast Feeding

Unsafe

Teriflunomide may pass into breast milk. Your doctor will make a decision whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.

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Driving

Caution

Scleteri 14mg Tablet may cause dizziness. So, drive or operate machinery only if you are alert.

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Liver

Caution

Scleteri 14mg Tablet is not recommended in patients with severe liver impairment. If you have a history of liver disease, inform your doctor before taking Scleteri 14mg Tablet .

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Kidney

Caution

Do not take Scleteri 14mg Tablet if you have a serious kidney problem which requires dialysis. If you have a history of kidney disease, inform your doctor before taking Scleteri 14mg Tablet .

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Children

Caution

Scleteri 14mg Tablet is not recommended for children as the safety and effectiveness have not been established.

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