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  3. Septran Oral Suspension 60 ml

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Septran Oral Suspension

Septran Oral Suspension belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Septran Oral Suspension does not work against infections caused by the virus, including cold and flu. 

Septran Oral Suspension is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Oral Suspension stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Your doctor will decide the dose and duration of Septran Oral Suspension based on your condition and the severity of the infection. In some cases, you may experience certain common side-effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side-effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Before starting Septran Oral Suspension, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Septran Oral Suspension on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Septran Oral Suspension if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Septran Oral Suspension is not recommended for children below 12years.

Uses of Septran Oral Suspension

Bacterial infections

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.

Medicinal Benefits

Septran Oral Suspension belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Septran Oral Suspension is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Oral Suspension kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Septran Oral Suspension is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Septran Oral Suspension if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Septran Oral Suspension if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Septran Oral Suspension to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Septran Oral Suspension 60 ml:
Taking Tranylcypromine with Septran Oral Suspension 60 ml can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Septran Oral Suspension 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Co-administration of Septran Oral Suspension 60 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Septran Oral Suspension 60 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Taking Safinamide with Septran Oral Suspension 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Septran Oral Suspension 60 ml is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
sulfamethoxazoleClozapine
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
The combined use of Septran Oral Suspension 60 ml and clozapine may increase the risk or severity of toxicity.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Septran Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
The combined use of Septran Oral Suspension 60 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Septran Oral Suspension 60 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Co-administration of Clonidine and Septran Oral Suspension 60 ml may increase the risk and severity of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Septran Oral Suspension 60 ml, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Using Granisetron together with Septran Oral Suspension 60 ml can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Co-administration of Granisetron with Septran Oral Suspension 60 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of the following symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, diarrhea, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations it is recommended to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Using Septran Oral Suspension 60 ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Sumatriptan and Septran Oral Suspension 60 ml, you can take these medicines together if prescribed by your doctor. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Septran Oral Suspension 60 ml:
Taking Paroxetine with Septran Oral Suspension 60 ml can cause sedation, dry mouth, blurred vision, constipation.

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Septran Oral Suspension 60 ml, you can take these medicines together if prescribed by your doctor. However, if you experience dry mouth, blurred vision, constipation contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Septran Oral Suspension 60 ml:
Using Septran Oral Suspension 60 ml together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Mirtazapine and Septran Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs like feeling confused, seeing or hearing things that aren't there, having a seizure, a fast heartbeat, a high temperature, sweating a lot, shaking, having trouble seeing clearly, muscle spasms or stiffness, difficulty moving, stomach pain, feeling sick, throwing up, or having diarrhea, make sure to call a doctor right away. They will be able to help you." Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Septran Oral Suspension is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Septran Oral Suspension kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.

Septran Oral Suspension causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Septran Oral Suspension. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Septran Oral Suspension and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Septran Oral Suspension even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Septran Oral Suspension for as long as your doctor has prescribed to treat your condition effectually.

Do not take Septran Oral Suspension on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Septran Oral Suspension may affect certain laboratory test results. Inform the person doing the tests that you are taking Septran Oral Suspension.

Septran Oral Suspension may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Septran Oral Suspension.

Drug-Drug Interactions Checker List

  • GLIBENCLAMIDE
  • AZITHROMYCIN
  • METRONIDAZOLE
  • ALBUTEROL
  • BENDROFLUMETHIAZIDE
  • GLICLAZIDE

Special Advise

  • Septran Oral Suspension may affect certain laboratory test results such as blood tests. Inform the person doing the tests that you are taking Septran Oral Suspension. 
  • Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed Septran Oral Suspension for a longer duration, to know if the medicine is working properly.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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