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Reviewed By Sunny S , MBBS
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Composition :

LOPERAMIDE-2MG

Manufacturer/Marketer :

Vanguard Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Sestil-AD Tablet

Sestil-AD Tablet contains an anti-diarrheal medication, primarily used to treat diarrhea in Inflammatory Bowel Disease and Short Bowel Syndrome by decreasing over-active bowel, including sudden diarrhea. Diarrhea is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhea is a common problem and generally lasts for one or two days, whereas chronic diarrhea lasts four weeks.

Sestil-AD Tablet contains Loperamide, which is a gastrointestinal medication primarily used to treat diarrhea. It works on the opiate receptor in the gut and slows down the intestines' contraction, thereby decreasing the speed at which the contents pass through it. This allows more time for reabsorption of fluids and nutrients, making the stools more solid and less frequent. It should not be used in patients with dysentery (diarrhea with blood).

Take Sestil-AD Tablet as prescribed by your doctor. You are advised to take Sestil-AD Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Sestil-AD Tablet are headache, nausea, and constipation. They do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Diarrhea can cause water loss and electrolyte imbalance, so drink plenty of fluids to help keep yourself hydrated. It is important to avoid this medicine if you have blood in your stool or if you are severely constipated. Let your doctor know about all other medications you are taking as some may affect or be affected by this medicine. And also, avoid drinking alcohol while taking Sestil-AD Tablet as it can worsen your sleepiness.

Uses of Sestil-AD Tablet

Diarrhea

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Sestil-AD Tablet contains Loperamide, which is an anti-diarrheal medication, primarily used to treat diarrhea in Inflammatory Bowel Disease and Short Bowel Syndrome by decreasing over-active bowel, including sudden diarrhea. Loperamide is a gastro-intestinal medication that works by slowing down the contraction of the intestines thereby decreasing the speed at which the contents pass through it. This allows more time for reabsorption of fluids and nutrients, making the stools more solid and less frequent. It should not be used in patients with dysentery (diarrhea with blood).

Storage

Store in a cool and dry place away from sunlight
Side effects of Sestil-AD Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take Sestil-AD Tablet if you are allergic to Sestil-AD Tablet or any of its ingredients. It is important to avoid this medicine if you have blood in your stool or if you are severely constipated. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. Diarrhea can cause water loss and electrolyte imbalance, so drink plenty of fluids to help keep yourself hydrated. Also, as a precautionary measure, you are recommended not to consume junk food items from outside. It may also cause dizziness, so do not operate car or any machinery which requires recommendtil you knowconsumingow this m oredicine affects you. And also, avoid drinking alcohol while taking Sestil-AD Tablet as it can worsen your sleepiness.

Drug-Drug Interactions

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LoperamideAmiodarone
Severe
LoperamideBepridil
Severe

Drug-Drug Interactions

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LoperamideAmiodarone
Severe
How does the drug interact with Sestil-AD Tablet:
Coadministration of Sestil-AD Tablet with amiodarone can significantly increase Sestil-AD Tablet levels which can increase the risk of a abnormal heart rhythm.

How to manage the interaction:
Taking Sestil-AD Tablet with amiodarone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, rapid heartbeat, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LoperamideBepridil
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with bepridil may raise Sestil-AD Tablet levels in the blood significantly, this might result in side effects like abnormal heart rhythm. Additional heart conditions, and electrolyte imbalances (e.g., magnesium or potassium loss from severe or prolonged diarrhoea or vomiting) may potentially increase your susceptibility.

How to manage the interaction:
Although taking Sestil-AD Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
LoperamideItraconazole
Severe
How does the drug interact with Sestil-AD Tablet:
Coadministration of itraconazole with Sestil-AD Tablet may significantly increase the risk of abnormal heart rhythm.

How to manage the interaction:
Sestil-AD Tablet and itraconazole have the potential to interact, however they can still be used if a doctor prescribes them. If you suffer any of the following symptoms, seek medical attention : dizziness, lightheadedness, fainting, shortness of breath, or racing heartbeats. Never discontinue taking a drug without consulting a doctor.
LoperamideDelavirdine
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with delavirdine may raise blood levels of Sestil-AD Tablet, and your risk of developing major problems including abnormal heart rhythm increases. Other cardiac conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
There may be a possibility of interaction between Sestil-AD Tablet and Delavirdine, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
LoperamideRanitidine bismuth citrate
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with ranitidine bismuth citrate may raise blood levels of Sestil-AD Tablet, you run the risk of developing major problems including abnormal heart rhythm. Other heart conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
There may be a possibility of interaction between Sestil-AD Tablet and Ranitidine bismuth citrate, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
LoperamideAbiraterone
Severe
How does the drug interact with Sestil-AD Tablet:
When taken in combination, abiraterone may considerably raise Sestil-AD Tablet levels in the blood and cause irregular heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with abiraterone together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
LoperamideLapatinib
Severe
How does the drug interact with Sestil-AD Tablet:
When taken in combination lapatinib may significantly raise the Sestil-AD Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with lapatinib together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideDronedarone
Severe
How does the drug interact with Sestil-AD Tablet:
When taken in combination dronedarone may significantly raise the Sestil-AD Tablet levels in the blood. This can lead to severe complications, such as abnormal heartbeat.

How to manage the interaction:
Although taking Sestil-AD Tablet with dronedarone together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeats while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
LoperamideCiclosporin
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with ciclosporin can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Although taking Sestil-AD Tablet with Ciclosporin together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not exceed the dose and frequency or duration of use of Sestil-AD Tablet advised by the doctor. Do not stop using any medications without talking to a doctor.
LoperamideEsketamine
Severe
How does the drug interact with Sestil-AD Tablet:
When esketamine and Sestil-AD Tablet are taken together, adverse symptoms such as fatigue, disorientation, trouble focusing, and problems with thinking, judgment, response time, and motor coordination may worsen.

How to manage the interaction:
Co-administration of Sestil-AD Tablet with Esketamine can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to avoid dehydration and electrolyte imbalance.
  • Avoid alcohol consumption with Sestil-AD Tablet as it may cause tiredness, drowsiness, or lack of concentration.
  • Eat small meals at short intervals. Eat food that is at room temperature.
  • Fired and oily food should not be taken as it might worsen your condition.
  • Do mild to moderate exercise.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Sestil-AD Tablet Substitute

Substitutes safety advice
  • Lopamide Tablet 10's

    by Others

    2.25per tablet
  • Lomofen Plus Tablet 20's

    by AYUR

    2.52per tablet
  • Loparet Tablet 10's

    by Others

    2.30per tablet
  • Andial Tablet 10's

    by Others

    2.20per tablet
  • Ridol 2mg Tablet 10's

    by Others

    2.03per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sestil-AD Tablet contains Loperamide which belongs to an opiate class that works by slowing down the contraction of the intestines thereby decreasing the speed at which the contents pass through it. This allows more time for reabsorption of fluids and nutrients, making the stools more solid and less frequent.

Yes, diarrhea is known to cause dehydration because of the excessive fluid loss in stools. So, to maintain fluid level, increase fluid intake to avoid excessive dehydration.

No, Sestil-AD Tablet can not be used for stomach pain, but Sestil-AD Tablet may lower the pain caused in the stomach due to diarrhea. Before taking Sestil-AD Tablet for stomach pain, please consult your doctor.

No, it should not be used to treat opioid withdrawal symptoms as a huge amount of Sestil-AD Tablet will be required, leading to heart complications.

No, Sestil-AD Tablet is a short medication to treat acute cases of diarrhea. If used as a long term medication, it may lead to side effects like constipation.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • QUINIDINE
  • DESMOPRESSIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • GEMFIBROZIL
  • DIPHENHYDRAMINE
  • CETIRIZINE

Special Advise

  • Diarrhea can cause electrolyte imbalance, so please maintain it by drinking plenty of water.

Disease/Condition Glossary

Diarrhoea: It is a condition in which bowel movements are too frequent leading to loose, watery stools. Acute diarrhea is a common probelm and generally lasts for one or two days whereas chronic diarrhea lasts for four weeks. Diarrhea can be due to  infections, antibiotics, diseases (inflammatory bowel disease), and other medicines.

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