Setolac P Tablet 10's belongs to the class of medications called ‘analgesics’ used to treat pain associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, etc. Osteoarthritis is a degenerative bone disease in which the tissue supporting the joints wears down. Rheumatoid arthritis is a condition in which the immune system attacks its own tissue leading to joint pain and inflammation. Ankylosing spondylitis is the inflammation of the spine and large joints.

Setolac P Tablet 10's contains Etodolac and Paracetamol. Etodolac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an analgesic. They act by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation. The inhibition of these substances can cause a decrease in symptoms such as pain, joint stiffness, and tenderness.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Setolac P Tablet 10's are nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, dizziness, headache, tiredness, rash, ringing in your ears, clay or black-colored stools, and increased heartbeat. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Setolac P Tablet 10's if you are allergic to any contents of it. Setolac P Tablet 10's should not be used in patients with a history of ulcers in the stomach or intestine, have had an allergic reaction to NSAIDs have severe liver, kidney, heart failure, and alcoholic liver disease. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly patients. It is not advised to consume alcohol as it may increase the risk of stomach bleeding. Setolac P Tablet 10's may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Setolac P Tablet 10's is used in the treatment of pain, swelling, and inflammation associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. It contains Etodolac and Paracetamol. It acts by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation.

• Nausea
• Vomiting
• Stomach pain
• Indigestion
• Diarrhea
• Constipation
• Dizziness
• Headache
• Tiredness
• Rash
• Ringing in your ears
• Black or clay-colored stools
• Increased heartbeat

Before taking Setolac P Tablet 10's, inform your doctor if you have high blood pressure, high cholesterol, diabetes, heart disease, heart attack or stroke, blood clot, stomach bleeding, asthma, edema (fluid overload), smoking habit, and liver, kidney disease. Inform your doctor immediately if you cough up or vomit blood or notice black or tarry stools, as it can be a sign of stomach bleeding. Setolac P Tablet 10's increases skin sensitivity to the sun, so avoid prolonged exposure to sunlight, sunlamps, and tanning beds.

Drug-Drug Interactions: Setolac P Tablet 10's may interact with blood thinners (warfarin), medicine that can suppress the immune system (cyclosporine), anticancer agent (methotrexate), an antidepressant (lithium), water pills, a steroid medicine (prednisone), medicines used to treat nausea and vomiting (metoclopramide and domperidone), and medicine used to lower cholesterol levels (cholestyramine).

Drug-Food Interactions: Do not consume alcohol as it may increase the risk of stomach bleeding and liver damage.  

Drug-Disease Interactions: Setolac P Tablet 10's should not be used in patients with ulcers in the stomach or intestine who have had an allergic reaction to NSAIDs and have severe liver, kidney, heart failure, and alcoholic liver disease.

• WARFARIN
• CYCLOSPORINE
• METHOTREXATE
• LITHIUM
• PREDNISONE
• METOCLOPRAMIDE
• DOMPERIDONE
• CHOLESTYRAMINE

• Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
• In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

• Do not take any over-the-counter (OTC) allergy or pain medicines without consulting your doctor. Most of these medicines contain an NSAID or analgesic (pain reliever), similar to Etodolac or Paracetamol present in Setolac P Tablet 10's.
• It may take up to 2 weeks to improve your symptoms. So, inform your doctor if your symptoms don’t improve within 2 weeks.
• Your doctor may monitor liver and kidney function if Setolac P Tablet 10's is prescribed for the long term.

Osteoarthritis: Osteoarthritis is the common type of arthritis in which the cartilage that cushions the bone's ends erodes due to wear and tear over time. Common symptoms are joint pain and stiffness.

Rheumatoid arthritis (RA): Rheumatoid arthritis (RA) is an autoimmune disease in which the immune cells attack the joints and cause bone erosion leading to severe pain and swelling. It may lead to joint deformity if left untreated.

Ankylosing spondylitis: Ankylosing spondylitis is a type of arthritis in which inflammation is seen in the spine and large joints. It led to pain and stiffness in the back and affected joints.