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About SEVEPIME FORTE 1000/125MG INJECTION
SEVEPIME FORTE 1000/125MG INJECTION belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.
SEVEPIME FORTE 1000/125MG INJECTION is a combination of two medicines: Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Tazobactam is a beta-lactamase inhibitor. It can improve the spectrum of antibacterial action by inhibiting the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime). SEVEPIME FORTE 1000/125MG INJECTION is only used to treat bacterial infections and is not recommended for viral infections.
SEVEPIME FORTE 1000/125MG INJECTION will be administered by a healthcare professional; do not self-administer. The common side effects of SEVEPIME FORTE 1000/125MG INJECTION are pain and swelling at the injection site and skin rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take SEVEPIME FORTE 1000/125MG INJECTION if you are allergic to penicillin, any cephalosporin antibiotic, or its contents. Before taking SEVEPIME FORTE 1000/125MG INJECTION, inform your doctor if you have kidney problems, diabetes, gastrointestinal problems, especially colitis (inflammation of the large intestine), or use other antibiotics. Do not discontinue or abruptly stop using SEVEPIME FORTE 1000/125MG INJECTION as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). This medicine is not recommended in children aged less than two years. SEVEPIME FORTE 1000/125MG INJECTION should be used with caution in pregnant women, breastfeeding mothers and elderly people. SEVEPIME FORTE 1000/125MG INJECTION may interact with alcohol. SEVEPIME FORTE 1000/125MG INJECTION may not affect your ability to drive.
Uses of SEVEPIME FORTE 1000/125MG INJECTION
Directions for Use
Medicinal Benefits
SEVEPIME FORTE 1000/125MG INJECTION contains Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic, whereas Tazobactam is a beta-lactamase inhibitor. SEVEPIME FORTE 1000/125MG INJECTION has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple moderate to severe bacterial infections such as urinary tract infections (UTI), skin infections, intra-abdominal infections, lower respiratory tract (lung) infections such pneumonia (inflammation of the air sacs present in lungs) and bronchitis (inflammation of the bronchi), septicemia (including infections of the bloodstream), and empiric treatment in febrile neutropenic patients (development of fever in patients with low neutrophil count).
Storage
Drug Warnings
SEVEPIME FORTE 1000/125MG INJECTION should be used with caution in patients with kidney impairment. There is a risk of serious adverse events such as confusion, hallucinations, stupor (a state of near-unconsciousness), and seizures (fits). SEVEPIME FORTE 1000/125MG INJECTION may cause Clostridium difficile-associated diarrhoea (CDAD), ranging from mild diarrhea to fatal colitis (inflammation of the large intestine). If CDAD is suspected or confirmed, the doctor may discontinue therapy and advise appropriate fluid and electrolyte management, protein supplementation, and antibiotic therapy to treat CDAD. A SEVEPIME FORTE 1000/125MG INJECTION may cause positive direct Coomb’s test, which indicates antibodies against red blood cells. So, it is necessary to let your doctor know that you are taking this medicine before undergoing laboratory tests. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. SEVEPIME FORTE 1000/125MG INJECTION may cause superinfection (additional infection caused by other microbes) on prolonged use.
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Side Effects of SEVEPIME FORTE 1000/125MG INJECTION
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SEVEPIME FORTE 1000/125MG INJECTION is used to treat bacterial infections. It contains Cefepime and Tazobactam. Cefepime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Tazobactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (cefepime).
The common side-effects of SEVEPIME FORTE 1000/125MG INJECTION are pain and swelling at the injection site, diarrhea, nausea, vomiting, headache and skin rash. These side-effects are usually mild and temporary. However, inform your doctor immediately if any of these side-effects persist or get worse.
In individuals who have kidney problems, colitis (inflammation of the intestine), and diabetes, SEVEPIME FORTE 1000/125MG INJECTION should be used with caution as this medicine may worsen the condition.
SEVEPIME FORTE 1000/125MG INJECTION may cause diarrhoea like most of the antibiotics. So, if you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor immediately. Taking plenty of fluids may help in preventing dehydration. Do not take any medicine on your own to treat diarrhoea.
People allergic to penicillin should not take SEVEPIME FORTE 1000/125MG INJECTION as they may develop cross-sensitivity (sensitivity to drugs with similar structures). SEVEPIME FORTE 1000/125MG INJECTION contains cefepime, which has a similar structure to that of penicillin.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.
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Alcohol
Caution
SEVEPIME FORTE 1000/125MG INJECTION may interact with alcohol. Consult your doctor before consuming any alcohol.
Pregnancy
Caution
SEVEPIME FORTE 1000/125MG INJECTION is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if prescribed by a doctor.
Breast Feeding
Caution
SEVEPIME FORTE 1000/125MG INJECTION may pass into breast milk in small amounts. So, caution should be exercised when given to breastfeeding mothers.
Driving
Safe if prescribed
SEVEPIME FORTE 1000/125MG INJECTION may not affect your ability to drive.
Liver
Caution
SEVEPIME FORTE 1000/125MG INJECTION should be used with caution in patients with live diseases. The dose may have to be adjusted by your doctor.
Kidney
Caution
SEVEPIME FORTE 1000/125MG INJECTION should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
Caution
SEVEPIME FORTE 1000/125MG INJECTION is not recommended for children below two years of age. It can be used safely in children above two years. Please consult your doctor for more information.