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  1. Home
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  3. Sevneph-400 Tablet 10's

Sevneph-400 Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Synonym :

SEVELAMER CARBONATE

Composition :

SEVELAMER-400MG

Manufacturer/Marketer :

Enphamed Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sevneph-400 Tablet

Sevneph-400 Tablet belongs to a group of medications called phosphate binder (which decreases the level of phosphate in the body). It is primarily used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Sevneph-400 Tablet contains sevelamer that works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes.

Take Sevneph-400 Tablet exactly as directed by your doctor. The most common side effects of Sevneph-400 Tablet are vomiting, upper abdominal pain, nausea, diarrhoea, stomach ache, indigestion, and flatulence. However, if the side effects persist, contact your doctor.

The use of Sevneph-400 Tablet is restricted in persons with a known history of allergic to any of the ingredients present in this medicine, have low levels of phosphate in their blood, and have a bowel obstruction. Sevneph-400 Tablet contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevneph-400 Tablet . Tell your doctor if you are facing swallowing problems, motility (movement) in your stomach and bowel, being sick frequently, active inflammation of the bowel,  have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. If you are pregnant or breastfeeding, please consult your doctor before taking Sevneph-400 Tablet .

Uses of Sevneph-400 Tablet

Hyperphosphatemia (high phosphorus level in blood)

Directions for Use

Tablet: Sevneph-400 Tablet should be taken as prescribed by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Take Sevneph-400 Tablet as prescribed by the doctor. Before taking, disperse the tablet in the prescribed amount of water, mix well and then swallow it. Do not crush, chew or swallow as a whole.Powder/granules: Firstly, shake the container and open the cap. Add the powder of the packet to a cup containing two teaspoonfuls (30 ml) of water. Mix well and make your child drink within 30 minutes. It is advised not to give more than the prescribed dose of medicine.

Medicinal Benefits

Sevneph-400 Tablet belongs to a group of medications called phosphate binder, which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes. Sevneph-400 Tablet controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sevneph-400 Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Drug Warnings

You should avoid taking Sevneph-400 Tablet if you are allergic to Sevneph-400 Tablet . Speak to your doctor if you have swallowing disorders, digestive tract surgery, severe constipation, have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. It should be used with caution if you are pregnant or planning to become pregnant. Sevneph-400 Tablet should not be recommended for breastfeeding mothers as it passes into breast milk. Avoid alcohol consumption while taking Sevneph-400 Tablet as it might cause unpleasant side effects. The safety and effectiveness of children under six years of age have not been established, so a Sevneph-400 Tablet should not be given to them. Sevneph-400 Tablet contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevneph-400 Tablet . Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is advised while taking Sevneph-400 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
SevelamerEnoxacin
Severe
SevelamerGemifloxacin
Severe

Drug-Drug Interactions

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SevelamerEnoxacin
Severe
How does the drug interact with Sevneph-400 Tablet:
Co-administration of Enoxacin and Sevneph-400 Tablet can decrease the blood levels and effectiveness of Enoxacin.

How to manage the interaction:
Co-administration of Enoxacin and Sevneph-400 Tablet can lead to an interaction, but it can be taken if advised by your doctor. Do not stop using any medications without a doctor's advice.
SevelamerGemifloxacin
Severe
How does the drug interact with Sevneph-400 Tablet:
Gemifloxacin's efficiency can be decreased by Sevneph-400 Tablet if it prevents the drug from being absorbed into the bloodstream. this is caused by the combined use of gemifloxacin and Sevneph-400 Tablet.

How to manage the interaction:
Co-administration of enoxacin and Sevneph-400 Tablet can lead to an interaction, but it can be taken if your doctor advises. It has been advised to separate the dosing of these medications by at least 4 hours and consult the doctor if your symptoms do not improve. Do not stop using any medications without a doctor's advice.
SevelamerErgocalciferol
Severe
How does the drug interact with Sevneph-400 Tablet:
Co-administration of Sevneph-400 Tablet with Ergocalciferol can decrease the effects of Ergocalciferol.

How to manage the interaction:
Co-administration of Sevneph-400 Tablet with Ergocalciferol can lead to an interaction, but they can be taken if advised by your doctor. Consult the doctor if your symptoms worsen. Do not stop using any drugs without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take fresh fruits, vegetables, rice, milk, un-enriched corn and rice cereals, and soda without phosphate additives in your regular diet.
  • Avoid or limit high phosphorus addictive foods (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
  •  Avoid intake of alcoholic beverages with Sevneph-400 Tablet as it can make you dehydrated and may increase the side effects. 
  • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate and will help you overcome some.
  • Sevneph-400 Tablet is preferably taken with meals as it can bind to dietary phosphate and prevent its absorption into the bloodstream. Drink it with a full glass of water.
  • Do not stop taking the Sevneph-400 Tablet dose until your doctor says so.
  • Do not use Sevneph-400 Tablet if you have a history of bowel obstruction.

Habit Forming

No

Therapeutic Class

HYPOPHOSPHATEMIC AGENT

Sevneph-400 Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:30 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sevneph-400 Tablet is in a class of medications called phosphate binders. Sevneph-400 Tablet works by holding onto phosphate from the diet so that it can pass out of your body.

No, ciprofloxacin may interfere with the working of Sevneph-400 Tablet ; therefore, it should not be taken simultaneously as Sevneph-400 Tablet .

Sevneph-400 Tablet works by holding onto phosphate from the food so that it can pass out of your body. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels.

Yes, constipation is the common side effect of Sevneph-400 Tablet , though it does not occur in everyone. Please consult your doctor if the side effect becomes severe and disturb you.

Yes, serum phosphate levels should be monitored regularly while you are taking Sevneph-400 Tablet . The use of Sevneph-400 Tablet may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.

No, Sevneph-400 Tablet is a class of medications called phosphate binder used to control the phosphate level in blood. If you stop taking Sevneph-400 Tablet , your phosphate levels may elevate again. Please consult your doctor.

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • MYCOPHENOLATE SODIUM
  • LEVOTHYROXINE SODIUM
  • ERDAFITINIB

Special Advise

  • Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is recommended while taking Sevneph-400 Tablet .

Disease/Condition Glossary

Hyperphosphatemia: Hyperphosphatemia is defined as an increased phosphate level in the blood. This condition is often a complication of chronic kidney disease. Phosphate is an important electrolyte. It strengthens your bones and teeth and produces energy.  When phosphate levels increase in the blood due to kidney impairment (the kidney does not remove extra phosphate out of the body), this can cause muscle problems and increase the risk of weak bones, heart attacks, and strokes. It is more common in people with chronic kidney disease and people on dialysis. Symptoms may include itchy skin, red eyes, bone pain, and fractures.

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