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Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma

About Sfil 300 mcg Injection 1's

Sfil 300 mcg Injection 1's belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, bacterial infections or other conditions. Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections.

Sfil 300 mcg Injection 1's contains ' Filgrastim ' that stimulates the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Sfil 300 mcg Injection 1's is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection, and before stem cell donation.

You are advised to take Sfil 300 mcg Injection 1's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as thrombocytopenia (low platelets level), anaemia (low red blood cell), headache, diarrhoea, vomiting, nausea, alopecia (unusual hair loss), tiredness, soreness, swelling of the digestive tract, fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Sfil 300 mcg Injection 1's for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Sfil 300 mcg Injection 1's if you are pregnant or planning for pregnancy. Sfil 300 mcg Injection 1's should not be taken by breastfeeding mothers unless prescribed. Sfil 300 mcg Injection 1's should be given to children under strict medical supervision. Please tell your doctor before using Sfil 300 mcg Injection 1's if you have sickle cell anaemia, as Sfil 300 mcg Injection 1's may cause sickle cell crisis and osteoporosis (bone disease). Regular blood tests will be taken to monitor the number of white blood cells in the body. Inform your doctor about your health condition and medicines to rule out unpleasant side effects. Sfil 300 mcg Injection 1's is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees celsius else its efficacy might get lost. Do not store in the freezer or the fridge.

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Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Sfil 300 mcg Injection 1's

Neutropenia (low number of white blood neutropenia cells),  Neutropenia during Chemotherapy,  Neutropenia after Bone marrow transplantation,  Neutropenia in patients with HIV infection,  peripheral blood stem cell mobilisation (to stimulate stem cells to enter the bloodstream to be collected and used in bone marrow transplantation)

Medicinal Benefits

Sfil 300 mcg Injection 1's contains ‘Filgrastim’ is a white blood cell growth factor. It belongs to a group of proteins called cytokines and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. Sfil 300 mcg Injection 1's works by stimulating the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Sfil 300 mcg Injection 1's is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection and before stem cell donation.

Side Effects of Sfil 300 mcg Injection 1's

  • Thrombocytopenia (low platelets level)
  • Anaemia (low red blood cell)
  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Alopecia (unusual hair loss)
  • Tiredness
  • Soreness and swelling of the digestive tract
  • Fever

Directions for Use

Sfil 300 mcg Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Sfil 300 mcg Injection 1's if you are allergic to Sfil 300 mcg Injection 1's or any of its ingredients it may contain inactive ingredients (such as dry natural rubber/latex in the needle cover on the prefilled syringe), which can cause allergic reactions or other problems. Before starting treatment with Sfil 300 mcg Injection 1's, inform your doctor if you have sickle cell anaemia, osteoporosis (bone disease), kidney disease, liver disease, spleen problems, heart problems, and radiation treatment. Sfil 300 mcg Injection 1's can cause the spleen to become enlarged, and it could rupture (tear). Inform your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder. If you receive chemotherapy or bone marrow transplant, do not use Sfil 300 mcg Injection 1's within 24 hours before or 24 hours after you receive chemotherapy or bone marrow transplant.  Do not take Sfil 300 mcg Injection 1's if you are pregnant or breastfeeding unless prescribed by the doctor. Sfil 300 mcg Injection 1's can be given safely to children only when prescribed. Sfil 300 mcg Injection 1's may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Sfil 300 mcg Injection 1's as it could lead to increased drowsiness. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. 

Therapeutic Class

HEMATOPOIETIC

Drug-Drug Interactions

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FilgrastimBleomycin
Severe
FilgrastimOlaparib
Severe

Drug-Drug Interactions

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FilgrastimBleomycin
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Combining Sfil 300 mcg Injection 1's with Bleomycin can increase the risk of developing lung disorders.

How to manage the interaction:
There may be a possibility of interaction between Sfil 300 mcg Injection 1's and Bleomycin, it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
FilgrastimOlaparib
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Taking Sfil 300 mcg Injection 1's together with olaparib can reduce the effects of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Co-administration of Sfil 300 mcg Injection 1's with Olaparib can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
FilgrastimImatinib
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Taking Sfil 300 mcg Injection 1's together with Imatinib can reduce the effect of Sfil 300 mcg Injection 1's.

How to manage the interaction:
There may be a possibility of interaction between Sfil 300 mcg Injection 1's and Imatinib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimRomidepsin
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Coadministration of Sfil 300 mcg Injection 1's with Romidepsin can reduce the effect of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although there is an interaction between Sfil 300 mcg Injection 1's and Romidepsin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimMelphalan
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Co-administration of Sfil 300 mcg Injection 1's together with Melphalan can reduce the effect of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although taking Sfil 300 mcg Injection 1's and Melphalan together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
FilgrastimMitomycin
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Using Sfil 300 mcg Injection 1's together with mitomycin reduce the effects of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Co-administration of Sfil 300 mcg Injection 1's with Mitomycin can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
FilgrastimBrentuximab
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Coadministration of Sfil 300 mcg Injection 1's with Brentuximab can decrease the therapeutic effect of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although there is an interaction between Sfil 300 mcg Injection 1's and brentuximab, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimBusulfan
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Coadministration of Sfil 300 mcg Injection 1's with Busulfan can reduce the effects of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although there is a possible interaction between Sfil 300 mcg Injection 1's and Busulfan, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
FilgrastimAzacitidine
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Coadministration of Sfil 300 mcg Injection 1's with Azacitidine can reduce the effects of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although there is an interaction between Sfil 300 mcg Injection 1's and azacitidine, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimPentostatin
Severe
How does the drug interact with Sfil 300 mcg Injection 1's:
Using Sfil 300 mcg Injection 1's together with pentostatin can reduce the effect of Sfil 300 mcg Injection 1's.

How to manage the interaction:
Although there is a possible interaction between Sfil 300 mcg Injection 1's and Pentostatin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ALTRETAMINE
  • BUSULFAN
  • CLADRIBINE
  • PROCARBAZINE
  • PEGFILGRASTIM
  • DACARBAZINE
  • GEMTUZUMAB
  • DINUTUXIMAB
  • BEVACIZUMAB
  • ALEMTUZUMAB
  • CARBOPLATIN
  • BENDAMUSTINE

Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet, as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 

  • Avoid eating raw or undercooked food. 

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Limit alcohol consumption and quit smoking. 

Habit Forming

No

Special Advise

  • Constantly monitors the number of blood cells in your blood, and your bone density level while you are receiving treatment with Sfil 300 mcg Injection 1's.

  • Do not take any kind of immunization or vaccination without your doctor's approval while using Sfil 300 mcg Injection 1's.

Author Details

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Disease/Condition Glossary

Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections. It can be caused by diseases that damage the bone marrow like cancer chemotherapy, HIV or AIDS, infections or deficiencies in vitamins or minerals, such as vitamin B12, folate, or copper, and autoimmune diseases, including Crohn's disease, lupus, and rheumatoid arthritis. Severe chronic neutropenias arise from the failure of the bone marrow to produce adequate numbers of neutrophils that circulate in the blood. It appears that patients with severe chronic neutropenias are at greater risk of developing leukaemia (blood cancer) than are other people.

Sfil 300 mcg Injection 1's Substitute

Substitutes safety advice
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