Sildobig-D Tablet 10's is a combination of medicine primarily used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or urge to urinate more often and improve your ability to urinate. The prostate is a small, muscular gland in the male reproductive system. Enlargement of the prostate is called BPH common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder.

Sildobig-D Tablet 10's is a combination of two drugs, namely; Silodosin and Dutasteride. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Sildobig-D Tablet 10's reduces the BPH symptoms and improves your ability to urinate.

Take Sildobig-D Tablet 10's as prescribed. Your doctor will recommend how often you take Sildobig-D Tablet 10's based on your medical condition. In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually continue taking Sildobig-D Tablet 10's for as long as your doctor has prescribed it. Try not to stop taking it on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Sildobig-D Tablet 10's. Avoid consumption of alcohol as it may increase the side effects like dizziness and low blood pressure. If you take Sildobig-D Tablet 10's with any antihypertensive medicine, your blood pressure could suddenly drop to s life-threatening level. So avoid intake of Sildobig-D Tablet 10's with antihypertensive drugs.

Sildobig-D Tablet 10's is a combination of two drugs, namely; Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Sildobig-D Tablet 10's reduces the BPH symptoms and improves your ability to urinate.

• Headache
• Dizziness
• Nasal congestion (stuffy nose)
• Diarrhoea
• Ejaculation disorder
• Retrograde ejaculation
• Impotence
• Orthostatic hypotension (sudden lowering of blood pressure on standing)

Do not take Sildobig-D Tablet 10's if you are allergic to Sildobig-D Tablet 10's and ingredients in it. Consult your doctor before taking Sildobig-D Tablet 10's if you are taking medicines for the treatment of hypertension (high blood pressure). If you take Sildobig-D Tablet 10's with any antihypertensive medicine your blood pressure could suddenly drop to a life-threatening level. So avoid intake of Sildobig-D Tablet 10's with antihypertensive drugs. Do not take Sildobig-D Tablet 10's if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve. You are advised not to drive or operate heavy machinery after taking Sildobig-D Tablet 10's as it may cause dizziness. Avoid consuming alcohol along with Sildobig-D Tablet 10's as it could lead to increased dizziness and drowsiness. Older patients may be more sensitive to the side effects of Sildobig-D Tablet 10's, especially dizziness and low blood pressure when getting up from a sitting or lying position. Sildobig-D Tablet 10's should not be given to women and children less than 18 years of age.

Drug-Drug Interaction: Sildobig-D Tablet 10's interacts with medicines used to treat high blood pressure (prazosin, terazosin), drugs used to treat erectile dysfunction (sildenafil, tadalafil), azole antifungals (itraconazole, ketoconazole), HIV protease inhibitor (lopinavir, ritonavir).

Drug-Food Interaction: Sildobig-D Tablet 10's may interact with grapefruit juice, alcohol, and tobacco. This may cause more side effects than it normally does. So, a Sildobig-D Tablet 10's should not be taken along with them.

Drug-Disease Interaction: Sildobig-D Tablet 10's should not be taken in patients with heart problems, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve.

• PRAZOSIN
• TERAZOSIN
• SILDENAFIL
• TADALAFIL
• ITRACONAZOLE
• KETOCONAZOLE
• LOPINAVIR
• RITONAVIR

• Maintaining a healthy weight, eating a balanced diet, and regular exercising may help your bladder empty at a normal rate.
• Avoid consumption of alcohol to treat your condition effectively as consuming an excessive amount of alcohol may make you pee more and can irritate your bladder.
•  Limit the amount of fluids and caffeine you drink, especially before you go out or go to bed.
• Stay warm, cold can make it feel more urgent to pee.
• Avoid usage of tobacco.
• Do daily exercise to strengthen your pelvic floor muscles.

• Regularly monitor blood pressure is required while taking Sildobig-D Tablet 10's.

Benign Prostatic Hyperplasia (BPH): is an enlargement of the prostate gland. The prostate is a small, muscular gland in the male reproductive system. It is a common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder. Symptoms of BPH include frequent or urgent need to urinate, nocturia (increased frequency of urination at night, difficulty starting urination, inability to empty the bladder, painful urination, blood in the urine.