Sildura 4 Capsule Combipack belongs to the group of medicines called 'alpha-blockers' used to treat the symptoms of an enlarged prostate gland (benign prostatic hyperplasia - BPH) in men. Benign prostatic hyperplasia (BPH) is a condition in which there is an enlargement of the prostate gland due to the multiplication of the cells mostly in men above 50 years of age. The growth of the prostate gland is non-cancerous in nature.

Sildura 4 Capsule Combipack contains ‘Silodosin’ that works by blocking the receptors (alpha 1) located in the prostate, bladder and urethra (urine pipe), thereby relaxes the muscles of the bladder and prostate gland. This help in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass water, thereby increasing urine output and flow. 

You are advised to take Sildura 4 Capsule Combipack for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Sildura 4 Capsule Combipack may cause common side-effects such as ejaculation disorders (orgasm with reduced or no sperm), dizziness, diarrhoea, stuffy nose (nasal congestion), and orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have low blood pressure, liver or kidney disease. Sildura 4 Capsule Combipack is intended for use in men only; women should not take Sildura 4 Capsule Combipack, especially pregnant or breastfeeding women. Sildura 4 Capsule Combipack should not be given to children as safety and efficacy have not been established. Sildura 4 Capsule Combipack may cause dizziness, so drive with caution. Avoid or limit alcohol consumption along with Sildura 4 Capsule Combipack as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Sildura 4 Capsule Combipack belongs to the group of medicines called alpha-blockers used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia) mostly in men above 50 years of age. Sildura 4 Capsule Combipack works by blocking the receptors (alpha 1) located in the prostate, bladder and urethra (urine pipe), thereby relaxes the muscles of the bladder and prostate gland. This help in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass water, thereby increasing urine output and flow. 

• Ejaculation disorders (orgasm with reduced or no sperm)
• Dizziness
• Diarrhoea
• Stuffy nose (nasal congestion)
• Orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing)

Do not take Sildura 4 Capsule Combipack if you are allergic to Silodosin, any alpha 1 blockers or any of the components in Sildura 4 Capsule Combipack. Inform your doctor if you have low blood pressure, liver or kidney disease. Talk to your doctor before taking Sildura 4 Capsule Combipack if you are undergoing eye surgery (cataract surgery) as cases of intraoperative floppy iris syndrome (IFIS) have been found in some cases. Sildura 4 Capsule Combipack is intended for use in men only; women should not take Sildura 4 Capsule Combipack, especially pregnant or breastfeeding women. Sildura 4 Capsule Combipack should not be given to children as safety and efficacy have not been established. Sildura 4 Capsule Combipack may cause dizziness, so drive only if you are alert. Avoid or limit alcohol consumption along with Sildura 4 Capsule Combipack as it could lead to increased dizziness.

Drug-Drug Interactions: Sildura 4 Capsule Combipack may interact with antifungals (itraconazole, ketoconazole), blood pressure-lowering pills (verapamil, metoprolol, diltiazem), antiviral (ritonavir), immune-suppressing drugs (cyclosporine), antibiotics (clarithromycin, erythromycin), and erectile dysfunction pills (tadalafil, sildenafil).

Drug-Food Interactions: Avoid or limit alcohol consumption along with Sildura 4 Capsule Combipack as it could lead to increased dizziness.

Drug-Disease Interactions: Inform your doctor if you have hypotension (low blood pressure), liver impairment and severe kidney impairment.

• TADALAFIL
• SILDENAFIL
• TAMSULOSIN
• METOPROLOL
• ITRACONAZOLE
• KETOCONAZOLE
• VERAMAPIL
• DILTIAZEM
• CLARITHROMYCIN
• ERYTHROMYCIN

• Urinate as soon as you feel the urge.
• Avoid excess caffeine and alcohol consumption.
• Maintain a healthy diet and exercise regularly.
• Practice kegel exercises to strengthen pelvic muscles.
• Reduce stress levels by doing yoga or meditation. Nervousness can increase the frequency of urination.

If you have had cataract surgery, let your doctor know before taking Sildura 4 Capsule Combipack as it may affect the pupil of the eye during cataract surgery. In some cases, intraoperative floppy iris syndrome (IFIS) has been found.

Benign prostatic hyperplasia (BPH): The prostate is a small, muscular gland in the male reproductive system which surrounds the urethra. Benign prostatic hyperplasia is a condition in which there is an enlargement of the prostate gland which occurs due to the multiplication of the cells. This causes the prostate gland to swell, which leads to the squeezing of the urethra and limits the urine flow. The symptoms of benign prostatic hyperplasia include painful urination, difficulty in urination, excess urination, incomplete urination, leakage of urine, dribbling at the end of the urinary stream, and urgency in urination. An enlarged prostate is a normal condition in older men due to changes in male sex hormones.