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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Consume Type

OPHTHALMIC

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Simplovir Ophthalmic Gel 5 gm

Simplovir Ophthalmic Gel 5 gm belongs to the class of 'antivirals' used in treating herpes simplex keratitis. Herpes simplex keratitis is an infection that affects the cornea of the eye front surface of the eye) caused by the herpes simplex virus (HSV).

Simplovir Ophthalmic Gel 5 gm contains Gancyclovir, which works by killing and stopping the growth of the herpes simplex virus on the cornea. Thereby helping to treat herpes simplex keratitis.

Simplovir Ophthalmic Gel 5 gm is for ophthalmic (for the eye) use only. Avoid ingestion of this medicine. In case of accidental intake, consult your doctor immediately. Common side effects of Simplovir Ophthalmic Gel 5 gm include eye irritation, burning/stinging sensation at the site of application, temporary blurred vision, sensitivity to the light, swollen and runny eyes, inflammation of the eyelids, and foreign body sensation. These side effects may not occur in every patient using Simplovir Ophthalmic Gel 5 gm and gradually resolve over time if they occur. If the side effects persist longer or worsen, please seek a doctor's advice.

Inform your doctor if you are allergic to any component present in this medication. Pregnant and breastfeeding women should consult the doctor before using the Simplovir Ophthalmic Gel 5 gm. Simplovir Ophthalmic Gel 5 gm may cause temporary blurred vision; hence avoid driving or operating machinery. Avoid contact of the tip of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. Simplovir Ophthalmic Gel 5 gm should be used in children only when advised by a doctor.

Uses of Simplovir Ophthalmic Gel 5 gm

Herpes simplex keratitis

Directions for Use

Simplovir Ophthalmic Gel 5 gm is for ophthalmic use only. Wash your hands thoroughly before and after using Simplovir Ophthalmic Gel 5 gm. Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops or a tiny amount of gel, as advised by the doctor, into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Replace the outer cap after use. Do not touch the container’s tip to the eye, eyelids or surrounding areas as it may contaminate Simplovir Ophthalmic Gel 5 gm.

Medicinal Benefits

Simplovir Ophthalmic Gel 5 gm treats viral infection of the eye caused by the herpes simplex virus. It consists of Gancyclovir, an antiviral drug that works by killing and stopping the growth of the herpes simplex virus on the cornea.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Simplovir Ophthalmic Gel 5 gm

  • Eye irritation
  • Sensitivity to the light
  • Swollen and runny eyes
  • Inflammation of the eyelids
  • Foreign body sensation
  • Stinging/burning sensation
  • Temporary blurred vision 

Drug Warnings

 

Inform your doctor if you are allergic to any of the components in Simplovir Ophthalmic Gel 5 gm. Do not touch the tip of the dispensing container with bare hands, or take it closer to the eyelids to prevent contamination. If you wear contact lenses, remove them while administering the medicine to the eye. It is advised to check with your doctor before using the Simplovir Ophthalmic Gel 5 gm if you are pregnant or breastfeeding. Avoid driving or operating machines until you have clear vision since Simplovir Ophthalmic Gel 5 gm may cause temporary blurred vision.

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
GanciclovirCladribine
Severe

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Coadministration of cidofovir with Simplovir Ophthalmic Gel 5 gm can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Simplovir Ophthalmic Gel 5 gm and Cidofovir hence it is not recommended to be taken together, but it can be taken only if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GanciclovirCladribine
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Taking cladribine together with Simplovir Ophthalmic Gel 5 gm may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Cladribine with Simplovir Ophthalmic Gel 5 gm can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GanciclovirClozapine
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Clozapine can cause higher levels of Simplovir Ophthalmic Gel 5 gm in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Simplovir Ophthalmic Gel 5 gm and Clozapine, you can take these medicines together if prescribed by a doctor. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, weight loss, or pain, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GanciclovirInfliximab
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Combining Infliximab with Simplovir Ophthalmic Gel 5 gm can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Simplovir Ophthalmic Gel 5 gm and Infliximab, but it can be taken if prescribed by a doctor. If you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate contact your doctor immediately. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
GanciclovirCertolizumab
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Using Simplovir Ophthalmic Gel 5 gm together with certolizumab may increase the risk of serious infections.

How to manage the interaction:
Taking Simplovir Ophthalmic Gel 5 gm with certolizumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirGolimumab
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Using Simplovir Ophthalmic Gel 5 gm together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Simplovir Ophthalmic Gel 5 gm and Golimumab, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor immediately. Do not stop using any medications without a doctor's advice.
GanciclovirAdalimumab
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Using Simplovir Ophthalmic Gel 5 gm together with adalimumab may increase the risk of serious infections.

How to manage the interaction:
Taking Simplovir Ophthalmic Gel 5 gm with adalimumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirTenofovir alafenamide
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
When Tenofovir alafenamide is taken with Simplovir Ophthalmic Gel 5 gm, the amount of Tenofovir alafenamide in the blood can go up. This can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Tenofovir alafenamide and Simplovir Ophthalmic Gel 5 gm, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
GanciclovirMaribavir
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
Coadministration of Simplovir Ophthalmic Gel 5 gm with Maribavir may alter the effectiveness of both these medications. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Maribavir and Simplovir Ophthalmic Gel 5 gm together can possibly result in an interaction; it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
GanciclovirTenofovir disoproxil
Severe
How does the drug interact with Simplovir Ophthalmic Gel 5 gm:
coadministration of Tenofovir disoproxil with Simplovir Ophthalmic Gel 5 gm can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
Although taking Simplovir Ophthalmic Gel 5 gm and Tenofovir disoproxil together can cause an interaction, it can be taken if your doctor has suggested it. If you have symptoms like feeling sick, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat -contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  •  
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always wash your hands before inserting and removing the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.

 

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Simplovir Ophthalmic Gel 5 gm Substitute

Substitutes safety advice
  • Gancigel Ophthalmic Gel 5 gm

    by Others

    28.62per tablet
  • Gansecure 0.15% Eye Gel 5 gm

    by Others

    27.00per tablet
  • L-Vir Ophthalmic Gel 5 gm

    by Others

    25.02per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

 

Disease/Condition Glossary

Herpes simplex keratitis: This is an eye infection caused when the herpes simplex virus affects the cornea (clear front surface of the eye). Symptoms include eye pain, tearing, redness, foreign body sensation, and sensitivity to light. 

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