Sinarest-AF Syrup 60 ml

Written By Divya L , PharmaD

Reviewed By Veda Maddala , M Pharmacy

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MRP ₹142.5

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Whats That

About Sinarest-AF Syrup 60 ml

Sinarest-AF Syrup 60 ml is a respiratory medication, primarily used to treat symptoms of common cold and allergies. The common cold is a respiratory illness that affects the nose and throat and is caused by viruses known as 'rhinoviruses'. The virus enters the body through the nose, mouth, or eyes and spreads easily through air droplets when a sick person sneezes, coughs or talks. Allergy is an immune response produced by the body in response to 'allergens', which releases 'histamines' into the blood. Histamines are the chemicals released into the body due to this immune response and cause a stuffy nose, watery eyes, itching nose/throat, etc.

Sinarest-AF Syrup 60 ml consists of four medicines, namely: Chlorpheniramine maleate(anti-allergic), Phenylephrine (decongestant), Sodium Citrate (mucolytic), and Menthol (organic compound). Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also provides temporary relief from sneezing, watery and itchy eyes, and runny nose caused by hay fever and other upper respiratory allergies. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. It is a vasoconstrictor (narrows blood vessels) and is used as a cardiotonic (favourable effect on the heart) agent. Sodium Citrate is a 'mucolytic agent' that makes sputum less viscous and easier to cough out. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Take Sinarest-AF Syrup 60 ml with or without food as advised by your doctor. Some people may experience nausea, vomiting, headache, and sleepiness. Most of these side effects of Sinarest-AF Syrup 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sinarest-AF Syrup 60 ml or any other medicines, please tell your doctor. If you have high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver, and urinary problems, please inform your doctor before taking Sinarest-AF Syrup 60 ml. If you are pregnant or planning to conceive, it is advised to tell your doctor before taking Sinarest-AF Syrup 60 ml. Do not use Sinarest-AF Syrup 60 ml in breastfeeding mothers without a doctor's advice as it may be excreted into breast milk and cause harm to the baby. Sinarest-AF Syrup 60 ml is not recommended for children below four years of age.

Uses of Sinarest-AF Syrup 60 ml

Common cold and allergies.

Directions for Use

Shake the bottle well before use. Check the label for directions and take it with or without food with a measuring cup in the dose and duration as prescribed by the doctor.

Medicinal Benefits

Sinarest-AF Syrup 60 ml is a respiratory medication, primarily used to treat symptoms of common cold and allergies. Sinarest-AF Syrup 60 ml consists of four medicines: Chlorpheniramine maleate (anti-allergic), Phenylephrine (decongestant), Sodium Citrate (mucolytic), and Menthol (organic compound). Chlorpheniramine maleate is an antihistamine agent (anti-allergic) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also provides temporary relief from sneezing, watery and itchy eyes and runny nose caused by hay fever and other upper respiratory allergies. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. It is a vasoconstrictor (narrows blood vessels) and is used as a cardiotonic (favourable effect on heart) agent. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Storage

Keep out of sight and reach of children.

Side effects of Sinarest-AF Syrup 60 ml

Sedation

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Let your doctor know if you have any allergic reactions to Sinarest-AF Syrup 60 ml, high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver and urinary problems before taking Sinarest-AF Syrup 60 ml. If you are pregnant or planning to conceive, it is advised to inform your doctor before taking Sinarest-AF Syrup 60 ml. Do not use Sinarest-AF Syrup 60 ml in breastfeeding mothers without doctor's advice since Chlorpheniramine in Sinarest-AF Syrup 60 ml may be excreted into breast milk and cause harm to the baby. Sinarest-AF Syrup 60 ml is not recommended for children below four years of age. Avoid consuming alcohol along with Sinarest-AF Syrup 60 ml as it could lead to increased drowsiness. Drive only if you are alert since Sinarest-AF Syrup 60 ml may cause sleepiness/shakiness/increased heart rate in some people.

Drug-Drug Interactions

PhenylephrineFurazolidone

Critical

PhenylephrineSelegiline

Critical

Drug-Drug Interactions

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PhenylephrineFurazolidone

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Furazolidone with Sinarest-AF Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Sinarest-AF Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Sinarest-AF Syrup 60 ml only after 14 days of stopping Furazolidone.

PhenylephrineSelegiline

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Selegiline with Sinarest-AF Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Sinarest-AF Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.

PhenylephrineTranylcypromine

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Tranylcypromine with Sinarest-AF Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Sinarest-AF Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

PhenylephrineSevoflurane

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Sinarest-AF Syrup 60 ml with Sevoflurane can increase the levels of Sinarest-AF Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

PhenylephrinePropofol

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml with Propofol may lead to increased levels of Sinarest-AF Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

ChlorpheniraminePotassium citrate

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

ChlorpheniraminePotassium chloride

Critical

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.

PhenylephrineTopiramate

Severe

How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Sinarest-AF Syrup 60 ml.

How to manage the interaction:
Although there is a possible interaction between Sinarest-AF Syrup 60 ml and Topiramate, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.

PhenylephrineMethysergide

Severe

How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml and Methysergide together may lead to side effects like increased blood pressure, stomach problems, and gangrene (death of tissues, usually in the arm or leg, that may require surgical treatment).

How to manage the interaction:
Although there is a possible interaction between Sinarest-AF Syrup 60 ml and Methysergide, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms like severe stomach pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe headache, irregular heartbeat, breathing difficulties, blurred vision, confusion, and/or slurred speech, consult the doctor immediately.

PhenylephrineAmoxapine

Severe

How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Amoxapine and Sinarest-AF Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml and Amoxapine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. It is advised to maintain blood pressure. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Take Sinarest-AF Syrup 60 ml as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Sinarest-AF Syrup 60 ml.
Know your triggers like allergens, such as pollen, dust and food items that make your asthma and other respiratory diseases severe.
Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
Drink extra fluids while you take Sinarest-AF Syrup 60 ml to help loosen congestion and lubricate the throat.
Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
Learning breathing exercises will help you move more air in and out of your lungs.

Side Effects of Sinarest-AF Syrup 60 ml

Nausea
Vomiting
Headache
Sleepiness/drowsiness.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Author Details

Written By

Divya L

PharmaD

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:43 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Sinarest-AF Syrup 60 ml work?

Sinarest-AF Syrup 60 ml treats symptoms of common cold and allergies and consists of Chlorpheniramine maleate, Phenylephrine, Sodium Citrate, and Menthol. Chlorpheniramine maleate is an antihistamine that blocks the action of histamine (a substance responsible for causing allergic reactions). Phenylephrine is a decongestant that works by contracting and narrowing the nasal blood vessels. Sodium citrate is a cough thinner that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Menthol is a cooling agent that relieves minor irritation in the throat due to allergy and provides a cooling sensation.

Should I use Sinarest-AF Syrup 60 ml on empty stomach, before food or after food?

Sinarest-AF Syrup 60 ml should preferably be used after taking your meal to decrease the occurrence of side effects. Please follow your doctor's advice on how you should use this medicine.

In which conditions, should I stay cautious while using Sinarest-AF Syrup 60 ml?

Inform your doctor before taking Sinarest-AF Syrup 60 ml, if you have any high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver and urinary problems.

What happens if I miss a dose of Sinarest-AF Syrup 60 ml?

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

How to store and dispose of Sinarest-AF Syrup 60 ml?

Store Sinarest-AF Syrup 60 ml according to the instructions on the leaflet and away from direct sunlight. Do not freeze and dispose of unused medicine. Keep it out of reach from pets and children.

Drug-Drug Interactions Checker List

DIPHENHYDRAMINE
CETIRIZINE
DULOXETINE
SERTRALINE
DEXTROMETHORPHAN
HYDROCODONE
ALPRAZOLAM
DEXTROAMPHETAMINE
AMPHETAMINE
METHYLPHENIDATE

Special Advise

You are recommended to inform your doctor that you are taking Sinarest-AF Syrup 60 ml before undergoing any medical tests or surgery.
It is advised to stop using Sinarest-AF Syrup 60 ml if your cough persists for more than one week and consult your doctor.

Disease/Condition Glossary

Common cold: It is a respiratory illness that affects the nose and throat and is caused by viruses known as 'rhinoviruses'. The virus enters the body through the nose, mouth or eyes and spreads easily through air droplets when a sick person sneezes, coughs or talks.

Allergy is an immune response produced by the body in response to 'allergens', which release 'histamines' into the blood. Histamines are the chemicals released into the body due to this immune response and cause a stuffy nose, watery eyes, itching nose/throat etc.