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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS

Sitaday M 1000 Tablet is a combination drug of Sitagliptin (DPP4 inhibitors) and Metformin (Biguanides) belongs to the class of anti-diabetic. Type 2 diabetes is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts but it is not able to act on the organs of the body.

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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

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Not Returnable

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About Sitaday M 1000 Tablet

Sitaday M 1000 Tablet is a combination drug of Sitagliptin (DPP4 inhibitors) and Metformin (Biguanides) belongs to the class of anti-diabetic. Type 2 diabetes is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts but it is not able to act on the organs of the body.

Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors which works by increasing the amounts of certain natural substances that lower blood sugar when it is high. Another medicine Metformin belongs to the class of biguanides which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Together, it prevents blood glucose levels from rising to very high levels after meals.

Sitaday M 1000 Tablet should be taken with food to avoid an upset stomach. Sitaday M 1000 Tablet should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. The most common side effect of Sitaday M 1000 Tablet is hypoglycemia (low blood glucose levels) characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, upper respiratory symptoms.

Sitaday M 1000 Tablet should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Sitaday M 1000 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Sitaday M 1000 Tablet should not be taken if you have type 1 diabetes mellitus, severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, is or planning to get pregnant or breastfeeding.

Uses of Sitaday M 1000 Tablet

Type 2 Diabetes Mellitus

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

 Sitaday M 1000 Tablet helps your pancreas to produce more insulin, make effective utilization of insulin, and decreases excess of sugar that your liver makes. It helps in controlling rise of blood sugar level in your body after meal. Besides this, it does not cause weight gain in the prolonged use. Sitaday M 1000 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sitaday M 1000 Tablet

  • Low blood sugar

  • Runny nose

  • Sore throat

  • Upper lung infection

  • Diarrhoea

  • Nausea

  • Vomiting

  • Gas

  • Stomach upset

  • Indigestion

  • General weakness

  • Headache

Drug Warnings

Sitaday M 1000 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Sitaday M 1000 Tablet , might develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid is accumulated in the blood, which can damage the working of your liver and kidney required to eliminate excess lactic acid from the blood. Before you start taking Sitaday M 1000 Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 levels. Sitaday M 1000 Tablet , when used with insulin, Sitaday M 1000 Tablet may lower the blood sugar level, leading to hypoglycaemia, which can be fatal. In this case, your doctor may adjust the dose by lowering the insulin dose or Sitaday M 1000 Tablet . Prolonged intake of Sitaday M 1000 Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. You should stop using Sitaday M 1000 Tablet for a short time before an X-ray procedure.

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
MetforminIoglicic acid
Critical

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Sitaday M 1000 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
MetforminIoglicic acid
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Ioglicic acid with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Iohexol with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Ioglycamic acid with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Iopromide with Sitaday M 1000 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Sitaday M 1000 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Sitaday M 1000 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Ioversol with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Iotroxic acid with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Iopentol with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Sitaday M 1000 Tablet:
Co-administration of Iopanoic acid with Sitaday M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Sitaday M 1000 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are lots of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase the intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Keep your blood pressure as normal (140/90) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Sitaday M 1000 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors which work by increasing the amounts of certain natural substances that lower blood sugar when it is high. Another medicine Metformin belongs to the class of biguanides which lowers glucose production in the liver, delays glucose absorption from the intestines and increases the body's sensitivity to insulin. Together, it prevents blood glucose levels from rising to very high levels after meals.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

Lactic acidosis is a rare but life-threatening condition when there is too much of lactic acid build up in the bloodstream. Long term intake of Sitaday M 1000 Tablet may lead to lactic acidosis when cells get deprived of the oxygen levels. Symptoms of lactic acidosis include a burning sensation of muscle, muscle ache, fast breathing, nausea, and stomach pain. Immediately contact the doctor in this complication.

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

Do not take excessive alcohol while taking Sitaday M 1000 Tablet , as this may increase the risk of a life-threatening condition called as lactic acidosis (too much of lactic acid in the body).

No. Sitaday M 1000 Tablet is only prescribed for the treatment of type 2 diabetes also called as 'non-insulin-dependent diabetes'.

Type 2 diabetes is a common form of diabetes in which the blood sugar-lowering hormone called insulin produced by the body does not function properly. Due to this, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. Diabetes, if left untreated or not treated properly, can cause long-term complications such as nerve damage, kidney damage, eye damage, foot problems, and also poses a high risk of developing heart diseases.

Drug-Drug Interactions Checker List

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Disease/Condition Glossary

Type 2 diabetes is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increase the chance of heart attack or stroke.

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