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  3. Sitahenz 50 mg Tablet 10's

Sitahenz 50 mg Tablet 10's, Pack of 10 TabletS
Sitahenz 50 mg Tablet 10's, Pack of 10 TabletS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

SITAGLIPTIN-50MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sitahenz 50Mg Tab

Sitahenz 50Mg Tab belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in treating type 2 diabetes in adults. Sitahenz 50Mg Tab is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.

Sitahenz 50Mg Tab contains sitagliptin. Sitahenz 50Mg Tab work by blocking the action of DPP-4 (an enzyme which destroys the hormone 'Incretin'). The enzyme 'Incretins' helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed.

Sitahenz 50Mg Tab should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Sitahenz 50Mg Tab is hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of the nose and throat with common cold) and headache.

Sitahenz 50Mg Tab should not be used in patients with type 1 diabetes and for treating diabetic ketoacidosis. Sitahenz 50Mg Tab should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Sitahenz 50Mg Tab abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Sitahenz 50Mg Tab should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeed. Prolonged intake of Sitahenz 50Mg Tab may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Sitahenz 50Mg Tab is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Sitahenz 50Mg Tab . Severe allergic reactions might occur in some patients taking Sitahenz 50Mg Tab like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Sitahenz 50Mg Tab in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Sitahenz 50Mg Tab should be closely monitored as severe drug interaction has been observed.

Uses of Sitahenz 50Mg Tab

Type 2 diabetes mellitus

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Sitahenz 50Mg Tab work by blocking the action of DPP-4 (an enzyme which destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed. Thus, Sitahenz 50Mg Tab plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sitahenz 50 mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Drug Warnings

Tell your doctor before consuming Sitahenz 50Mg Tab if you have allergic reactions to sitagliptin, any medications, foods, or any components present in Sitahenz 50Mg Tab . Prolonged intake of Sitahenz 50Mg Tab may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Sitahenz 50Mg Tab is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Sitahenz 50Mg Tab . Severe allergic reactions might occur in some patients taking Sitahenz 50Mg Tab like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Sitahenz 50Mg Tab in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Sitahenz 50Mg Tab should be closely monitored as severe drug interaction has been observed.

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
SitagliptinIvacaftor
Severe

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
How does the drug interact with Sitahenz 50 mg Tablet:
Co-administration of Sitahenz 50 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Sitahenz 50 mg Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
SitagliptinIvacaftor
Severe
How does the drug interact with Sitahenz 50 mg Tablet:
When Sitahenz 50 mg Tablet is taken with Ivacaftor, the amount of Sitahenz 50 mg Tablet in the blood can go up.

How to manage the interaction:
Taking Sitahenz 50 mg Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
SitagliptinTirzepatide
Moderate
How does the drug interact with Sitahenz 50 mg Tablet:
As tirzepatide and Sitahenz 50 mg Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Invest at least 150 min of your week in moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Losing weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replacing refined carbohydrates-containing foods with whole grain foods and increasing intake of fruits, veggies, and other fibre-enriched foods.
  • Reduce saturated fat intake (or hidden fats) in food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes or meditation or yoga.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (140/90) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Sitahenz 50Mg Tab Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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SITAGLIPTIN-50MGAcute pancreatitis
Severe
SITAGLIPTIN-50MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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SITAGLIPTIN-50MGAcute pancreatitis
Severe
How does the disease interact with Sitahenz 50 mg Tablet:
Pancreatitis: Patients using Sitahenz 50 mg Tablet may cause acute pancreatitis. Use cautiously in patients who have a history of pancreatitis or pancreatic disease are at higher risk. Monitor for pancreatitis symptoms and indications. Discontinue therapy if pancreatitis is suspected.

How to manage the interaction:
Sitahenz 50 mg Tablet should be used with caution in patients with a history of pancreatitis or pancreatic disease. Patients should be observed for signs and symptoms of pancreatitis during treatment and if pancreatitis is suspected, treatment should be discontinued immediately.
SITAGLIPTIN-50MGChronic kidney disease
Moderate
How does the disease interact with Sitahenz 50 mg Tablet:
Renal dysfunction: Assess renal function before initiating Sitahenz 50 mg Tablet therapy. Adjust the dose as per moderate to severe renal insufficiency. Otherwise, observed worsening renal function.

How to manage the interaction:
Dose adjustment may be needed in people with moderate to severe renal insufficiency and end stage renal dysfunction.

FAQs

Drug-Drug Interactions Checker List

  • BUPROPION
  • CEPHALEXIN
  • CIPROFLOXACIN
  • CIMETIDINE
  • DIGOXIN
  • DOLUTEGRAVIR
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  • TOPIRAMATE
  • LAMOTRIGINE
  • RANOLAZINE
  • ALPHA LIPOIC ACID
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  • PROTHIONAMIDE
  • PEGVISOMANT

Disease/Condition Glossary

Type 2 diabetes is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, weight gain may occur, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also include neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increased chance of heart attack or stroke.

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