SIZOPRIDE 50MG TABLET
₹98.6*
MRP ₹109.5
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₹93.5*
MRP ₹109.5
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SIZOPRIDE 50MG TABLET belongs to a group of medicines called 'antipsychotics' primarily used to treat long term (chronic) schizophrenia and postoperative nausea/vomiting. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). In schizophrenic disorders, there are positive symptoms (like delusions, hallucinations and thought disorders) along with negative symptoms (like blunted effect, emotional and social withdrawal). Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth.
SIZOPRIDE 50MG TABLET contains Amisulpride, which helps restore the balance of certain natural substances in the brain. The key action of SIZOPRIDE 50MG TABLET is to block some of the dopamine receptors in the brain and correct dopamine's overactivity. On the other hand, it also affects other brain neurotransmitters such as serotonin (5-HT), which may also lead to its beneficial effects. SIZOPRIDE 50MG TABLET also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.
SIZOPRIDE 50MG TABLET can be taken with or without food as prescribed by your doctor. You are advised to take SIZOPRIDE 50MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain side effects such as dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, increased prolactin level in blood. Most of these side effects of SIZOPRIDE 50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist for a longer duration, consult your doctor immediately.
SIZOPRIDE 50MG TABLET should be avoided if you are allergic to it or any other medicines. SIZOPRIDE 50MG TABLET is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, inform your doctor before taking SIZOPRIDE 50MG TABLET. Use SIZOPRIDE 50MG TABLET with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. If you have breast cancer, pheochromocytoma (tumor of the adrenal gland), pituitary gland prolactinoma (tumor of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking SIZOPRIDE 50MG TABLET. Avoid driving and op taking SIZOPRIDE 50MG TABLET as it may cause drowsiness or dizziness.
SIZOPRIDE 50MG TABLET contains Amisulpride, a group of medicines called antipsychotics used to treat a mental illness called schizophrenia, bipolar disorder. Additionally, SIZOPRIDE 50MG TABLET has anti-emetics properties used either monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. The key action of SIZOPRIDE 50MG TABLET is to block some of the brain's dopamine receptors and correct dopamine's overactivity, thereby producing a calming effect in the brain. Altogether, SIZOPRIDE 50MG TABLET may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life.
Drug-Drug Interaction: SIZOPRIDE 50MG TABLET may have interaction with medicines used to reduce heart rate (quinidine, disopyramide, amiodarone, sotalol) medicines for high blood pressure and heart problems (diltiazem, verapamil, guanfacine, digitalis, clonidine, bepridil) pain killers (morphine, pethidine, tramadol, indomethacin, aspirin, acetaminophen, hydrocodone) antimalarial (mefloquine), anti-histamines (promethazine, diphenhydramine), medicine used to treat schizophrenia (clozapine), neuroleptics (pimozide, haloperidol, imipramine, duloxetine, citalopram, sertraline, fluoxetine, paroxetine), anti-anxiety drugs (lorazepam and diazepam), antipsychotics (flupentixol, droperidol, haloperidol, fluphenazine, pipamperone), antibiotics (ciprofloxacin, erythromycin, sparfloxacin, moxifloxacin), antiparkinson (levodopa, ropinirole, bromocriptine).
Drug- Food Interaction: SIZOPRIDE 50MG TABLET may interact with grapefruit juice and alcohol. Therefore, avoid intake of grapefruit juice and alcohol with SIZOPRIDE 50MG TABLET as it may increase the risk of adverse effects.
Drug-Disease Interaction: If you have breast cancer, pheochromocytoma (tumour of the adrenal gland), pituitary gland prolactinoma (tumour of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking SIZOPRIDE 50MG TABLET.
Mental illness:
Nausea/Vomiting:
Schizophrenia (psychosis): It is a mental illness in which brain information processing is affected. Patients with schizophrenia develop symptoms such as hallucinations (see or hear unreal things), delusions (false beliefs) and become withdrawn from society. They lose the ability to differentiate reality from false beliefs Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, mental trauma. Schizophrenia may also occur due to traumatic brain injuries or other diseases.
Bipolar disorder: Patients with bipolar disorders have mood swings ranging from manic episodes of heightened excitement to severe depression. It used to be known as manic depression.
Nausea/Vomiting: It is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition and dehydration.
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Alcohol
Unsafe
Avoid consumption of alcohol while taking SIZOPRIDE 50MG TABLET as it may lead to increased dizziness and drowsiness.
Pregnancy
Caution
SIZOPRIDE 50MG TABLET should be used in pregnant women only when prescribed by a doctor. Consult your doctor before taking SIZOPRIDE 50MG TABLET if you are pregnant, your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Unsafe
SIZOPRIDE 50MG TABLET is unsafe and should not be taken by breastfeeding mothers. Consult your doctor for further advice.
Driving
Caution
SIZOPRIDE 50MG TABLET may cause dizziness, drowsiness and uncontrolled movements. Do not drive or operate machinery unless you are alert.
Liver
Caution
Take SIZOPRIDE 50MG TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. However, SIZOPRIDE 50MG TABLET is not recommended for patients with severe liver disease. Inform your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain or yellow discoloration of the eyes or skin.
Kidney
Caution
SIZOPRIDE 50MG TABLET should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.
Children
Unsafe
SIZOPRIDE 50MG TABLET should not be given to children as the safety and effectiveness were not established.
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