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  3. Skizoril MD 200 mg Tablet 10's

Skizoril MD 200 mg Tablet 10's, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Whats That

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Composition :

CLOZAPINE-200MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Skizoril MD 200mg Tablet

Skizoril MD 200mg Tablet belongs to a group of medicines called antipsychotics used to treat schizophrenia. Additionally, Skizoril MD 200mg Tablet is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Schizophrenia is a medical condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Skizoril MD 200mg Tablet contains ‘Clozapine’, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour and thoughts.

You are advised to take Skizoril MD 200mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Skizoril MD 200mg Tablet may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Skizoril MD 200mg Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor if you are pregnant. Do not take Skizoril MD 200mg Tablet if you are breastfeeding, as it may pass into breastmilk. Avoid driving as Skizoril MD 200mg Tablet may cause drowsiness and dizziness. Skizoril MD 200mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Skizoril MD 200mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Skizoril MD 200mg Tablet

Schizophrenia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water, do not chew or crush it.Orodispersible/Mouth dissolving tablet: Check the label for directions before use. Place the tablet in the mouth and allow it to dissolve.

Medicinal Benefits

Skizoril MD 200mg Tablet belongs to a group of medicines called antipsychotics. Skizoril MD 200mg Tablet is used to treat schizophrenia and to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Skizoril MD 200mg Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby helping in improving mood, behaviour and thoughts. Skizoril MD 200mg Tablet is used to treat schizophrenia when other antipsychotic drugs are ineffective or have caused severe adverse effects. Skizoril MD 200mg Tablet is also used to treat psychotic disorders in patients with Parkinson’s disease when standard treatments have failed.

Storage

Store in a cool and dry place away from sunlight
Side effects of Skizoril MD 200 mg Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

Do not take Skizoril MD 200mg Tablet if you are allergic to any of its contents if you have galactose intolerance, total lactase deficiency, glucose-galactose malabsorption, low number of white blood cells or if you are taking medicines that can cause low levels of white blood cells, bone marrow disorder, epilepsy, circulatory collapse (pronounced fall in blood pressure that can lead to unconsciousness), brain disorders, severe kidney disease, heart disease, liver disease with jaundice, liver failure or paralytic ileus (small intestine disorder). Inform your doctor if you have a low number of white blood cells or platelet count, orthostatic hypotension, epilepsy, enlarged prostate or difficulty urinating, glaucoma, severe constipation, diabetes, heart, liver or kidney problems. Consult your doctor if you are pregnant. Do not take Skizoril MD 200mg Tablet if you are breastfeeding, as it may pass into breastmilk.

Drug-Drug Interactions

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ClozapineRopinirole
Critical
ClozapineFlibanserin
Critical

Drug-Drug Interactions

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ClozapineRopinirole
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
When Ropinirole is taken with Skizoril MD 200 mg Tablet, it may not work as well.

How to manage the interaction:
Taking Ropinirole with Skizoril MD 200 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
ClozapineFlibanserin
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
When Flibanserin and Skizoril MD 200 mg Tablet are taken together, may increase side effects.

How to manage the interaction:
There may be a possibility of interaction between Skizoril MD 200 mg Tablet and Flibanserin, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, drowsiness, fatigue, and difficulty concentrating, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClozapineMetoclopramide
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
Co-administration of Metoclopramide with Skizoril MD 200 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Skizoril MD 200 mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
ClozapinePimozide
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
When Skizoril MD 200 mg Tablet is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 200 mg Tablet with Pimozide there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineSparfloxacin
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
When Skizoril MD 200 mg Tablet is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 200 mg Tablet with Sparfloxacin there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapinePotassium citrate
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
Taking Skizoril MD 200 mg Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Potassium citrate with Skizoril MD 200 mg Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ClozapineCisapride
Critical
How does the drug interact with Skizoril MD 200 mg Tablet:
When Skizoril MD 200 mg Tablet is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 200 mg Tablet with Cisapride there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineCeritinib
Severe
How does the drug interact with Skizoril MD 200 mg Tablet:
Taking Ceritinib with Skizoril MD 200 mg Tablet, may increase the risk of infections.

How to manage the interaction:
Taking Skizoril MD 200 mg Tablet with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineSorafenib
Severe
How does the drug interact with Skizoril MD 200 mg Tablet:
Coadministration of Skizoril MD 200 mg Tablet with Sorafenib can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Skizoril MD 200 mg Tablet with Sorafenib together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ClozapineImatinib
Severe
How does the drug interact with Skizoril MD 200 mg Tablet:
Co-administration of Imatinib with Skizoril MD 200 mg Tablet can increase the risk of neutropenia (low levels of neutrophils, a type of white blood cells in the blood).

How to manage the interaction:
Although there is an interaction, Imatinib can be taken with Skizoril MD 200 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include fruits, vegetables, and fibre-rich food in your diet.
  • Cut down on sugars, salts and saturated fats.
  • Drink enough fluids to stay hydrated.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Skizoril MD 200mg Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby improving mood, behaviour and thoughts.

Do not discontinue Skizoril MD 200mg Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Skizoril MD 200mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Skizoril MD 200mg Tablet .

Skizoril MD 200mg Tablet may cause agranulocytosis (low levels of white blood cells), making you more prone to infections. Consult your doctor immediately if you experience flu-like symptoms, sore throat or fever.

Dry mouth could be a side-effect of Skizoril MD 200mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Orthostatic hypotension could be a side-effect of Skizoril MD 200mg Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Skizoril MD 200mg Tablet may cause tachycardia (fast heartbeat). Talk to your doctor if you experience irregular or fast heartbeat even at rest, chest pain, unexplained tiredness or breathing problems.

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take your regular dose. Please don't take a double dose to make up for a missed one.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • HALOPERIDOL
  • LURASIDONE
  • LITHIUM
  • LORAZEPAM
  • ALPRAZOLAM
  • BENZTROPINE MESYLATE
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • DIVALPROEX SODIUM
  • CLONAZEPAM
  • LAMOTRIGINE

Special Advise

  • Regular monitoring of blood count is advised as Skizoril MD 200mg Tablet may cause agranulocytosis (low white blood cells).
  • Skizoril MD 200mg Tablet may cause blood lipids (fats) alteration, which could lead to weight gain. Your doctor might monitor your weight and blood lipid levels regularly.
  • If you have a liver disorder, regular liver function tests are recommended for as long as Skizoril MD 200mg Tablet has been prescribed.
  • Skizoril MD 200mg Tablet might cause thrombosis (blood clotting in the vein). If you are due to have any surgery, inform your doctor that you are taking Skizoril MD 200mg Tablet .
  • Skizoril MD 200mg Tablet might affect how your body controls temperature; therefore, be cautious while exercising, taking hot baths or sauna.

Disease/Condition Glossary

Schizophrenia: It is a severe mental illness in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Schizophrenia is a long-term disease that affects brain functioning. People with schizophrenia may seem like they have lost touch with reality, which might cause significant distress for the individual, their friends and family. The exact cause is unknown; however, conditions like genetics, environment, brain structure and function could be the risk factors. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc.

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