apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Sletral 25mg Tablet

Sletral 25mg Tablet, Pack of 1 Tablet
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

SERTRALINE-25MG

Manufacturer/Marketer :

Tripada Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Sletral 25mg Tablet

Sletral 25mg Tablet belongs to a class of antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs) used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Panic disorder is linked to anxiety with sudden feelings of fear when there is no danger in reality. PTSD is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression. Social anxiety disorder (social phobia) is associated with intense anxiety or distress in social situations.

Sletral 25mg Tablet contains Sertraline that works by inhibiting the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Sletral 25mg Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Sletral 25mg Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Sletral 25mg Tablet based on your medical condition. Some people may experience drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Most of these side effects of Sletral 25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sletral 25mg Tablet or any other medicines, please tell your doctor. Sletral 25mg Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and not treat any other conditions in children below 18 years of age. Sletral 25mg Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Sletral 25mg Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Sletral 25mg Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Sletral 25mg Tablet, inform your doctor as they may worsen in the initial days of taking Sletral 25mg Tablet. Do not take Sletral 25mg Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids as it may cause severe adverse effects.

Uses of Sletral 25mg Tablet

Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, Obsessive-compulsive disorder (OCD).

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral solution: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dropper.

Medicinal Benefits

Sletral 25mg Tablet contains Sertraline, an antidepressant that inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Sletral 25mg Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sletral 25mg Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

If you are allergic to Sletral 25mg Tablet or any other medicines, please tell your doctor. Sletral 25mg Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and does not treat any other conditions in children below 18 years of age. Sletral 25mg Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Sletral 25mg Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Sletral 25mg Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Sletral 25mg Tablet, inform your doctor as they may worsen in the initial days of taking Sletral 25mg Tablet. Do not take Sletral 25mg Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids pain killer as it may cause severe adverse effects. If you have diabetes, fits, bipolar disorder, bleeding disorders, glaucoma, severe diarrhoea, low sodium or potassium levels in the blood, neuroleptic malignant syndrome or serotonin syndrome (potentially life-threatening conditions), liver or heart problems, inform your doctor before taking Sletral 25mg Tablet. 

Drug-Drug Interactions

verifiedApollotooltip
SertralineLinezolid
Critical
SertralineZiprasidone
Critical

Drug-Drug Interactions

Login/Sign Up

SertralineLinezolid
Critical
How does the drug interact with Sletral 25mg Tablet:
When linezolid is taken with Sletral 25mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Linezolid and Sletral 25mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineZiprasidone
Critical
How does the drug interact with Sletral 25mg Tablet:
Co-administration of Sletral 25mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Sletral 25mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SertralineEliglustat
Critical
How does the drug interact with Sletral 25mg Tablet:
Coadministration of Eliglustat and Sletral 25mg Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Eliglustat and Sletral 25mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineDronedarone
Critical
How does the drug interact with Sletral 25mg Tablet:
Co-administration of Dronedarone and Sletral 25mg Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dronedarone with Sletral 25mg Tablet is not recommend, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineIsocarboxazid
Critical
How does the drug interact with Sletral 25mg Tablet:
Co-administration of Sletral 25mg Tablet with Isocarboxazid can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Isocarboxazid with Sletral 25mg Tablet there may be a possibility of interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineThioridazine
Critical
How does the drug interact with Sletral 25mg Tablet:
Co-administration of Thioridazine and Sletral 25mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine and Sletral 25mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations -contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineHalofantrine
Critical
How does the drug interact with Sletral 25mg Tablet:
Coadministration of halofantrine and Sletral 25mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Sletral 25mg Tablet and halofantrine, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineTranylcypromine
Critical
How does the drug interact with Sletral 25mg Tablet:
Taking Tranylcypromine and Sletral 25mg Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine and Sletral 25mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineProcarbazine
Critical
How does the drug interact with Sletral 25mg Tablet:
When Procarbazine is taken with Sletral 25mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Sletral 25mg Tablet and Procarbazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralinePimozide
Critical
How does the drug interact with Sletral 25mg Tablet:
Taking Sletral 25mg Tablet with pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
There may be a possibility of interaction between Pimozide and Sletral 25mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations-call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Regularly attend therapy sessions.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Sletral 25mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Sletral 25mg Tablet contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Sletral 25mg Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.

Yes, Sletral 25mg Tablet may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Sletral 25mg Tablet.

No, you are not recommended to take Sletral 25mg Tablet with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Sletral 25mg Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Yes, Sletral 25mg Tablet may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Sletral 25mg Tablet.

It takes about 2 weeks or longer, usually for Sletral 25mg Tablet to work. However, it is recommended to use Sletral 25mg Tablet for as long as your doctor has prescribed it for you.

Sletral 25mg Tablet may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.

Sletral 25mg Tablet should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Sletral 25mg Tablet, especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.

Drug-Drug Interactions Checker List

  • SELEGILINE
  • LINEZOLID
  • PIMOZIDE
  • HALOPERIDOL
  • PERPHENAZINE
  • OLANZAPINE
  • BUPRENORPHINE
  • FENTANYL
  • TRAMADOL
  • NALOXONE
  • WARFARIN
  • TICLOPIDINE
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • FLUCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • CLARITHROMYCIN
  • LEVOFLOXACIN
  • NEFAZODONE
  • FLUOXETINE
  • FLUVOXAMINE
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • DESIPRAMINE
  • LITHIUM
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • IBUPROFEN
  • ASPIRIN
  • TOLBUTAMIDE
  • CIMETIDINE
  • PANTOPRAZOLE
  • RABEPRAZOLE
  • OMEPRAZOLE
  • LANSOPRAZOLE
  • LEVOMEPROMAZINE

Special Advise

  • Sletral 25mg Tablet may interfere with a urine test. Therefore, it is advised to inform your doctor or lab technician that you are taking Sletral 25mg Tablet.

Disease/Condition Glossary

Depression: It is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.

Obsessive-compulsive disorder (OCD): It is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions) leading to repetitive behaviours (compulsions).

Panic disorder: It is linked to anxiety with sudden fear even when there is no danger in reality.

Post-traumatic stress disorder (PTSD): It is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression.

Social anxiety disorder: It is social phobia associated with intense anxiety or distress in social situations.

Have a query?

whatsapp Floating Button