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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

LETROZOLE-2.5MG

Manufacturer/Marketer :

Pharmanova Specialties Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Smartova-L Capsule

Smartova-L Capsule belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Smartova-L Capsule contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Smartova-L Capsule prevents the growth of cancer cells. Thereby Smartova-L Capsule helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Smartova-L Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Smartova-L Capsule may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Smartova-L Capsule if you are pregnant or breastfeeding. Smartova-L Capsule may cause drowsiness and dizziness, so drive only if you are alert. Smartova-L Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Smartova-L Capsule as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Smartova-L Capsule

Breast cancer

Directions for Use

Take Smartova-L Capsule with or without food. Swallow Smartova-L Capsule as a whole with a glass of water; do not chew or break it. Take Smartova-L Capsule at the same time every day.

Medicinal Benefits

Smartova-L Capsule belongs to the group of anti-cancer medicines called aromatase inhibitors. Smartova-L Capsule is used to treat breast cancer in women who have gone through menopause (cessation of periods). Smartova-L Capsule works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Smartova-L Capsule prevents the growth of cancer cells. Thereby, Smartova-L Capsule helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Smartova-L Capsule if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Smartova-L Capsule if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Smartova-L Capsule may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Smartova-L Capsule. Avoid taking Smartova-L Capsule if you are pregnant or breastfeeding. Smartova-L Capsule may cause drowsiness and dizziness, so drive only if you are alert. Smartova-L Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Smartova-L Capsule as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Smartova-L Capsule to rule out any side-effects. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Smartova-L Capsule:
Coadministration of thalidomide and Smartova-L Capsule may increase the risk of blood clots.

How to manage the interaction:
Although taking Smartova-L Capsule and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Smartova-L Capsule:
When taken together ethinyl estradiol may interfere with Smartova-L Capsule's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Smartova-L Capsule and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Smartova-L Capsule:
Co-administration of Smartova-L Capsule and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Smartova-L Capsule and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Smartova-L Capsule:
Co-administration of Smartova-L Capsule may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Smartova-L Capsule and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Smartova-L Capsule:
Smartova-L Capsule may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Smartova-L Capsule and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Smartova-L Capsule:
when taken together Smartova-L Capsule's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Smartova-L Capsule and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with Smartova-L Capsule:
When taken together Smartova-L Capsule's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Smartova-L Capsule and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Smartova-L Capsule:
Coadministration of Conjugated estrogens with Smartova-L Capsule may reduce the effect of Smartova-L Capsule.

How to manage the interaction:
Although taking Conjugated estrogen and Smartova-L Capsule together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Smartova-L Capsule:
Co-administration of Desogestrel together with Smartova-L Capsule may decrease the effects of Smartova-L Capsule.

How to manage the interaction:
Although taking Smartova-L Capsule and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Smartova-L Capsule works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Smartova-L Capsule prevents the growth of cancer cells. Thereby, Smartova-L Capsule helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Smartova-L Capsule causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Smartova-L Capsule. Regularly monitor blood pressure levels while taking Smartova-L Capsule. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Smartova-L Capsule on your own. You are advised to take Smartova-L Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Smartova-L Capsule.

Smartova-L Capsule may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Smartova-L Capsule.

Smartova-L Capsule may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Smartova-L Capsule may cause bone thinning due to reduction of estrogens in the body.
  • Smartova-L Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Smartova-L Capsule.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells which are stimulated by the female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.  

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