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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition :

CEFUROXIME-250MG

Manufacturer/Marketer :

Smotec Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Smorox 250mg Tablet

Smorox 250mg Tablet belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

Smorox 250mg Tablet is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take Smorox 250mg Tablet only if your doctor has prescribed you. Smorox 250mg Tablet is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with Smorox 250mg Tablet, you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of Smorox 250mg Tablet can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a Smorox 250mg Tablet effect on the mother or baby during pregnancy. However, one should take the Smorox 250mg Tablet with caution. Smorox 250mg Tablet is excreted in the breastmilk, so the nursing mother should cautiously take Smorox 250mg Tablet. This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. Smorox 250mg Tablet is not recommended for people allergic or hypersensitive to Smorox 250mg Tablet, penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with Smorox 250mg Tablet. Liver and kidney-affected people should take this medication with caution.

Uses of Smorox 250mg Tablet

Bacterial infections

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Smorox 250mg Tablet in doses as prescribed by your doctor with the help of a measuring cup.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the whole contents.

Medicinal Benefits

Smorox 250mg Tablet treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Smorox 250mg Tablet also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of Smorox 250mg Tablet is seven days (5-10 days). But, your doctor might prescribe you Smorox 250mg Tablet for a longer duration depending on the condition of infection. Smorox 250mg Tablet has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

Storage

Store in a cool and dry place away from sunlight
Side effects of Smorox 250mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.

Drug Warnings

Special care should be taken by the people taking Smorox 250mg Tablet who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of Smorox 250mg Tablet may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping Smorox 250mg Tablet. The case of colitis (inflammatory bowel disease) has been reported using Smorox 250mg Tablet. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking Smorox 250mg Tablet. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of Smorox 250mg Tablet immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking Smorox 250mg Tablet for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking Smorox 250mg Tablet should be warned to be cautious when driving or operating machinery.

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Smorox 250mg Tablet:
Co-administration of Smorox 250mg Tablet may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Smorox 250mg Tablet. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Smorox 250mg Tablet:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Smorox 250mg Tablet.

How to manage the interaction:
Although taking Smorox 250mg Tablet and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Smorox 250mg Tablet:
Co-administration of Dalteparin and Smorox 250mg Tablet can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Smorox 250mg Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Smorox 250mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Smorox 250mg Tablet to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Smorox 250mg Tablet.
  • Avoid intake of alcoholic beverages with Smorox 250mg Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Smorox 250mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Author Details

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Drug-Diseases Interactions

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CEFUROXIME-250MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-250MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-250MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Smorox 250mg Tablet:
Colitis: In some cases the use of Smorox 250mg Tablet may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Smorox 250mg Tablet should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-250MGChronic kidney disease
Moderate
How does the disease interact with Smorox 250mg Tablet:
Renal dysfunction: Smorox 250mg Tablet is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Smorox 250mg Tablet as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-250MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Smorox 250mg Tablet:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Smorox 250mg Tablet after dialysis or an additional dosage to be administered.

How to manage the interaction:
Smorox 250mg Tablet serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-250MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Smorox 250mg Tablet:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Smorox 250mg Tablet if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Smorox 250mg Tablet should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-250MGOther diseases of liver
Moderate
How does the disease interact with Smorox 250mg Tablet:
liver disease: With Smorox 250mg Tablet, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-250MGOther diseases of liver
Moderate
How does the disease interact with Smorox 250mg Tablet:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

FAQs

Smorox 250mg Tablet is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

You should avoid taking Smorox 250mg Tablet with oral birth control pills, medicines that reduces gastric acidity (like antacids, omeprazole), immuno suppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with thyphoid and BCG vaccines.

Depending upon the severity of your medical condition your doctor may prescribe it to you daily for a specific duration. The usual dose ofSmorox 250mg Tablet is 7 days (5-10 days), but depending on your current infection state your doctor may extend your dose intake for more days.

Try to stay well hydrated by drinking at least 6 glass of water or other fluid per day. Keep your underwear clean and try to use underwear made of cotton to avoid the spread of infection. Always keep your bladder empty as much possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat urinary tract infection.

After taking an antibiotic you may need to wait for up to three hours for eating or drinking any dairy products include milk as well as butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work dampen the effect of antibiotics.

If you have taken accidently over dosage of Smorox 250mg Tablet, you may have diarrhoea, nausea or vomiting. In rare cases it can also cause convulsion or seizures (fits). Try to reach out to doctor in this case.

No. Smorox 250mg Tablet treats only bacterial infection. Cough, flu or cold are usually caused due to the viruses. So, you should consult doctor for these conditions.

Yes. Smorox 250mg Tablet may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if your are using any birth control pills.

No. You should complete the full course of Smorox 250mg Tablet as your doctor prescribes. After completing the full course, the Smorox 250mg Tablet will work. You must take Smorox 250mg Tablet at the right dose, times, and for the right number of days.

Drug-Drug Interactions Checker List

  • OMEPRAZOLE
  • PROBENECID
  • MYCOPHENOLIC ACID

Disease/Condition Glossary

A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

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