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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Consume Type :

PARENTERAL

Return Policy :

Not Returnable

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About Sodium Bicarbonate Injection

Sodium Bicarbonate Injection is indicated in the treatment of metabolic acidosis and other conditions requiring systemic alkalinisation. It is also used to increase urinary pH to increase the solubility of certain weak acids, in treatment of certain intoxications to decrease renal absorption of the drug, severe diarrhoea accompanied by loss of bicarbonate, and poisoning by salicylates or methyl alcohol. Sodium Bicarbonate Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted.
 
Sodium Bicarbonate Injection contains ‘Sodium bicarbonate’, which acts as an electrolyte replenisher and systemic alkaliser. Thereby reducing the acid in the blood. Sodium Bicarbonate Injection helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid. 
 
Sodium Bicarbonate Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects, such as injection site reactions, irritability, muscle spasms, and low levels of potassium in the blood. You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Please consult your doctor if you have any concerns regarding the usage of Sodium Bicarbonate Injection in children. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Sodium Bicarbonate Injection

Metabolic acidosis, severe diarrhoea, drug intoxication, and poisoning.

Directions for Use

Sodium Bicarbonate Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Sodium Bicarbonate Injection is indicated in the treatment of metabolic acidosis caused due to diabetes, hepatitis, starvation, shock, cardiac arrest, renal insufficiency, severe dehydration, severe primary lactic acidosis, Addison’s disease or administration of acidic drugs and other conditions requiring systemic alkalinisation. It is also used to increase urinary pH to increase the solubility of certain weak acids, in treatment of certain intoxications to decrease renal absorption of the drug, severe diarrhoea accompanied by loss of bicarbonate, and poisoning by salicylates or methyl alcohol. Sodium Bicarbonate Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted. Sodium Bicarbonate Injection acts as an electrolyte replenisher and systemic alkaliser. Thereby reducing the acid in the blood. Sodium Bicarbonate Injection helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sodium Bicarbonate Injection

  • Injection site reactions
  • Irritability
  • Muscle spasms
  • Low levels of potassium in the blood

Drug Warnings

Do not take Sodium Bicarbonate Injection if you are allergic to any of its components; if you have kidney failure, heart failure, high blood pressure, low blood calcium/potassium/chloride, high blood sodium/pH, kidney stones, fluid retention, or hypoventilation (breathing problems). Inform your doctor if you have congestive heart failure, oedema with sodium-retaining conditions, or renal insufficiency. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding.

Drug-Drug Interactions

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Sodium bicarbonateGefitinib
Severe
Sodium bicarbonateDolutegravir
Severe

Drug-Drug Interactions

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Sodium bicarbonateGefitinib
Severe
How does the drug interact with Sodium Bicarbonate Injection 25 ml Injection 25 ml:
Taking Sodium Bicarbonate Injection 25 ml with Gefitinib together can reduce the levels and treatment outcomes of Gefitinib.

How to manage the interaction:
Although taking Gefitinib and Sodium Bicarbonate Injection 25 ml together can cause an interaction, it can be taken if a doctor has suggested it. Contact your doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
Sodium bicarbonateDolutegravir
Severe
How does the drug interact with Sodium Bicarbonate Injection 25 ml Injection 25 ml:
Co-administration of Sodium Bicarbonate Injection 25 ml and Dolutegravir reduces the levels of Dolutegravir, resulting in reduced effectiveness.

How to manage the interaction:
Although taking Dolutegravir and Sodium Bicarbonate Injection 25 ml together can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stay hydrated.
  • Avoid smoking and alcohol consumption. 
  • Maintain a healthy weight by regular exercising.
  • Include foods rich in nutrients and potassium.
  • Eat small, frequent meals slowly if you have diarrhoea.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Sodium Bicarbonate Injection Substitute

Substitutes safety advice
  • Bicarb 25% Injection

    by AYUR

    25.20per tablet
  • Bicarb Injection 25 ml

    by Others

    7.85per tablet
  • Lifecare Sodium Bicarbonate Injection

    by Others

    1.57per tablet
  • Sodium Bicarbonate 7.5% Injection 25 ml

    by Others

    1.01per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sodium Bicarbonate Injection acts as an electrolyte replenisher and systemic alkaliser. It reduces the acid in the blood.

Sodium Bicarbonate Injection is used to treat metabolic acidosis caused due to diabetes, hepatitis, starvation, shock, cardiac arrest, renal insufficiency, severe dehydration, severe primary lactic acidosis, Addison’s disease or administration of acidic drugs. Metabolic acidosis is an electrolyte disorder characterised by an acid-base imbalance in the body.

Sodium Bicarbonate Injection is indicated in severe diarrhoea, which is often accompanied by a significant loss of bicarbonate. Sodium Bicarbonate Injection helps by compensating for the lost bicarbonate ions.

Sodium Bicarbonate Injection is indicated for treating certain drug intoxication, such as barbiturates (in cases where barbiturate-protein complex dissociation is desired). Sodium Bicarbonate Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted.

Sodium Bicarbonate Injection is used in poisoning by methyl alcohol or salicylates and in haemolytic reactions that require the alkalinisation of urine to lower the nephrotoxicity of haemoglobin and its by-products.

Drug-Drug Interactions Checker List

  • PREDNISONE
  • QUINIDINE
  • FLECAINIDE
  • AMPHETAMINE
  • EPHEDRINE
  • PSEUDOEPHEDRINE
  • ASPIRIN
  • CHLORPROPAMIDE
  • MECAMYLAMINE
  • MEMANTINE
  • TETRACYCLINE
  • DOXYCYCLINE
  • METHENAMINE

Special Advise

  • False positive Labstix for urine protein may result due to the high urinary alkalinity produced by sodium bicarbonate. Therefore, inform the person doing the tests that you are on treatment with Sodium Bicarbonate Injection.
  • Regular monitoring of serum electrolyte concentration is advised.

Disease/Condition Glossary

Metabolic acidosis: It is an electrolyte disorder characterised by an acid-base imbalance in the body. The main causes of metabolic acidosis are loss of bicarbonate, increased acid production, and lowered ability of the kidney to excrete excess acids.

Drug intoxication: Drug intoxication is a condition that follows the administration of a psychoactive substance and results in disturbances in the level of consciousness, perception, cognition, behaviour, or other psychophysiological responses and functions.

Diarrhoea: It occurs when there is a frequent need to empty the bowels, characterised by loose and watery stools. The causes of diarrhoea include food intolerance, food allergy, adverse reaction to a medicine, viral infection, bacterial infection, intestinal disease, parasitic infection, and stomach or gallbladder surgery. The symptoms of diarrhoea include nausea, abdominal pain, cramps, dehydration and bloating, frequent urge to empty the bowels, and a large volume of stools or watery stools.

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