Solifirst 10 Tablet 10's

Solifirst 10 Tablet 10's belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination, and inability to control urination. Besides this, Solifirst 10 Tablet 10's is also used for the treatment of neurogenic detrusor overactivity (a bladder control condition caused by neurological problems) in children 2 years and above.

Solifirst 10 Tablet 10's contains ‘Solifenacin’ that relaxes the urinary bladder muscles which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder causing the patient to have frequent urges to urinate. Solifirst 10 Tablet 10's stops these sudden contractions of urinary bladder muscles thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder.

Take Solifirst 10 Tablet 10's as prescribed by the doctor. Common side-effects of Solifirst 10 Tablet 10's are dry mouth, blurred vision, constipation, nausea, dyspepsia (indigestion), abdominal pain, burping or belching, heartburn, and stomach upset. Inform your doctor if these side effects do not go away or get worse.

Do not take Solifirst 10 Tablet 10's if you are allergic to ‘solifenacin’ or any other ingredients present in it. Before taking Solifirst 10 Tablet 10's, inform your doctor if you have kidney disease, liver disease, bladder blockage, myasthenia gravis (a muscle disease), stomach or bowel problems (including constipation), glaucoma (increased pressure in the eye causing loss of vision), or a history of heart rhythm problems (including QT prolongation). Also, inform your doctor if you are pregnant or breastfeeding. Inform your doctor if you have an intolerance to sugars as this medicine contains lactose. Do not take grapefruit or grapefruit juice with this medication. Avoid driving or operating heavy machinery as this medicine may cause dizziness.

Solifirst 10 Tablet 10's contains ‘solifenacin’ that belongs to the class of medications called 'anticholinergics'. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder causing the patient to have frequent urges to urinate. Solifirst 10 Tablet 10's can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine that can be held by your bladder.

• Dry mouth
• Blurred vision
• Constipation
• Nausea
• Dyspepsia (indigestion)
• Urinary tract infections
• Blurred vision
• Abdominal pain
• Burping or belching
• Heartburn
• Stomach upset

Do not take Solifirst 10 Tablet 10's if you are allergic to ‘solifenacin’ or any contents of it. Before taking Solifirst 10 Tablet 10's, inform your doctor if you are pregnant or breastfeeding or if you have kidney disease, liver disease, bladder blockage, controlled narrow-angle glaucoma, or stomach or bowel problems (including constipation), or a history of heart rhythm problems (including QT prolongation). Solifirst 10 Tablet 10's has lactose, so inform your doctor if you have an intolerance to any sugars. Solifirst 10 Tablet 10's may cause dizziness or blurred vision. So, do not drive or operate any heavy machinery. It can increase body temperature by decreasing sweating. So, avoid hot weather or doing strenuous exercise as this may cause overheating leading to unwanted effects. 

Drug-Drug interactions: Solifirst 10 Tablet 10's may interact with other anticholinergic medicines, cholinergic drugs,  gastrointestinal agents (metoclopramide and cisapride), antifungal drugs (ketoconazole and itraconazole), drugs used to treat HIV (ritonavir and nelfinavir), antihypertensives (verapamil and diltiazem), antibiotic (rifampicin), antiepileptic drugs (phenytoin and carbamazepine), and bisphosphonates.

Drug-Food interactions: Do not take grapefruit or grapefruit juice while using Solifirst 10 Tablet 10's.

Drug-Disease interactions: Solifirst 10 Tablet 10's should be used with caution in patients with urinary retention (inability to urinate), severe stomach or bowel conditions, myasthenia gravis (a muscle disease), glaucoma (eye problem), kidney dialysis, severe liver disease, and severe kidney disease.

• METOCLOPRAMIDE
• CISAPRIDE
• KETOCONAZOLE
• RITONAVIR
• NELFINAVIR
• ITRACONAZOLE
• VERAPAMIL
• DILTIAZEM
• RIFAMPICIN
• PHENYTOIN
• CARBAMAZEPINE

• Eat fresh fruits like pears, banana, citrus fruits, and green vegetables like beans and potatoes. 
• Try to take cranberry juice as it helps in minimizing urinary infections. 
• Avoid coffee, tea, and carbonated drinks which contains caffeine. 
• Do not consume processed, fried, or spicy foods, as these foods can irritate your bladder. 
• Limit alcohol intake as it can increase the risk of side-effects.
• Quit smoking and exercise regularly. 

• Solifirst 10 Tablet 10's is not recommended for the children less than 2 years of age.
• Intake of Solifirst 10 Tablet 10's can make you sweat less, thereby increasing the chance of having a heat stroke in summer. So avoid doing tasks which may cause to overheat. 
• Intake of Solifirst 10 Tablet 10's may occasionally cause blurry vision and dizziness so avoid driving a motor vehicle, operate heavy machinery and performing hazardous tasks which require mental alertness as well. 

Overactive bladder (OAB): In normal conditions, when the urinary bladder is filled with urine, it sends a message to the brain that an individual is ready to urinate. During the urination process, bladder muscles contracts which ultimately leads to a uniform flow of urine. Contrary to this, in Overactive bladder (OAB), the urinary bladder muscles start contracting before the urine is filled in the urinary bladder, thereby causing frequent urges to urinate. Solifirst 10 Tablet 10's prevents these sudden bladder muscle contractions and increasing the volume and amount of urine that the bladder can hold. Thus, Solifirst 10 Tablet 10's helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.