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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

ISONIAZID-300MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Solonex Tablet 10's

Solonex Tablet 10's belongs to the group of medicines called anti-tubercular agents primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Solonex Tablet 10's does not work against infections caused by the virus.

Solonex Tablet 10's contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, Solonex Tablet 10's inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take Solonex Tablet 10's as prescribed. Use Solonex Tablet 10's for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of Solonex Tablet 10's. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If you are allergic to Solonex Tablet 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet 10's. Solonex Tablet 10's may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet 10's.  Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while on treatment with Solonex Tablet 10's as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet 10's.

Uses of Solonex Tablet 10's

Tuberculosis (TB)

Directions for Use

Take Solonex Tablet 10's on an empty stomach at least one hour before or two hours after a meal or as advised by your doctor. Do not take it with food. Tablet: Swallow it as a whole with a glass of water. Do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Solonex Tablet 10's contains isoniazid, an antibiotic used to treat and prevent tuberculosis. Solonex Tablet 10's prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, Solonex Tablet 10's may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Solonex Tablet 10's

  • Fever
  • Dizziness
  • Nausea
  • Stomach upset
  • Loss of appetite
  • Constipation
  • Tiredness
  • Numbness or tingling in the feet or hands

Drug Warnings

If you are known to be allergic to Solonex Tablet 10's, please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet 10's. Solonex Tablet 10's may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet 10's. Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking Solonex Tablet 10's as they might cause drug-food interaction. Avoid alcohol consumption with Solonex Tablet 10's as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet 10's.

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
IsoniazidLovastatin
Critical

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
How does the drug interact with Solonex Tablet:
When Lomitapide is taken with Solonex Tablet, Solonex Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Solonex Tablet:
When Lovastatin is taken with Solonex Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidRegorafenib
Critical
How does the drug interact with Solonex Tablet:
When Solonex Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Tablet is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidAlfentanil
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet will enhance the amount or action of Alfentanil when taken together.

How to manage the interaction:
Taking Alfentanil with Solonex Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
IsoniazidSonidegib
Severe
How does the drug interact with Solonex Tablet:
The combined use of Solonex Tablet and Sonidegib will enhance the amount of Sonidegib, which increases the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Sonidegib and Solonex Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
IsoniazidSimvastatin
Severe
How does the drug interact with Solonex Tablet:
The combined use of Solonex Tablet and Simvastatin will enhance the levels of Simvastatin, which increases the risk of side effects.

How to manage the interaction:
Co-administration of Simvastatin and Solonex Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
IsoniazidOmeprazole
Severe
How does the drug interact with Solonex Tablet:
When Omeprazole is taken with Solonex Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Omeprazole with Solonex Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
IsoniazidLeflunomide
Severe
How does the drug interact with Solonex Tablet:
Taking Solonex Tablet with Leflunomide can increase the risk and severity of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Solonex Tablet, it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash, itching, exhaustion, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
IsoniazidLemborexant
Severe
How does the drug interact with Solonex Tablet:
Co-administration of lemborexant and Solonex Tablet may increase the blood levels of lemborexant. This may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Lemborexant and Solonex Tablet, but it can be taken if prescribed by a doctor. However, if you experience depression, abnormal sleep behaviors, worsening of depression or suicidal thoughts, changes in heartbeat, or headache. Do not discontinue any medications without a doctor's advice.
IsoniazidCholera, live attenuated
Severe
How does the drug interact with Solonex Tablet:
Taking Solonex Tablet and Cholera, live attenuated together may reduce the effectiveness of the vaccine.

How to manage the interaction:
Although taking Solonex Tablet and Cholera, live attenuated together can cause an interaction, it can be taken if a doctor has suggested it. You shouldn't receive the cholera vaccination until at least 14 days after finishing your Solonex Tablet therapy in order to ensure an appropriate immune response. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks
Common Foods to Avoid:
Dark Chocolate, Cocoa, Coffee, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine containing products including chocolates(which contains caffeine) during Solonex Tablet treatment may lead to an interaction. Avoid caffiene and its products during treatment with Solonex Tablet.

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Solonex Tablet 10's Substitute

Substitutes safety advice
  • PYZINA KID TABLET

    by Others

    5.49per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking Solonex Tablet 10's to monitor your liver function.
  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.
  • A monthly liver function test is advisable while using Solonex Tablet 10's.

 

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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