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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

ISONIAZID-300MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Solonex Tablet

Solonex Tablet belongs to the group of medicines called anti-tubercular agents primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Solonex Tablet does not work against infections caused by the virus.

Solonex Tablet contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, Solonex Tablet inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take Solonex Tablet as prescribed. Use Solonex Tablet for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of Solonex Tablet . Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If you are allergic to Solonex Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet . Solonex Tablet may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet .  Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while on treatment with Solonex Tablet as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet .

Uses of Solonex Tablet

Tuberculosis (TB)

Directions for Use

Take Solonex Tablet on an empty stomach at least one hour before or two hours after a meal or as advised by your doctor. Do not take it with food. Tablet: Swallow it as a whole with a glass of water. Do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Solonex Tablet contains isoniazid, an antibiotic used to treat and prevent tuberculosis. Solonex Tablet prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, Solonex Tablet may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Solonex Tablet
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

If you are known to be allergic to Solonex Tablet , please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Solonex Tablet . Solonex Tablet may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking Solonex Tablet . Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking Solonex Tablet as they might cause drug-food interaction. Avoid alcohol consumption with Solonex Tablet as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking Solonex Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Solonex Tablet:
When Lovastatin is taken with Solonex Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
How does the drug interact with Solonex Tablet:
When Solonex Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Tablet is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidLomitapide
Critical
How does the drug interact with Solonex Tablet:
When Lomitapide is taken with Solonex Tablet, Solonex Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidHalofantrine
Severe
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet and Halofantrine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Solonex Tablet and Halofantrine together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Solonex Tablet:
The combined use of Solonex Tablet and Simvastatin will enhance the levels of Simvastatin, which increases the risk of side effects.

How to manage the interaction:
Co-administration of Simvastatin and Solonex Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solonex Tablet:
When Halothane is taken with Solonex Tablet, can increase the side affects of liver.

How to manage the interaction:
Co-administration of Solonex Tablet with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidSonidegib
Severe
How does the drug interact with Solonex Tablet:
The combined use of Solonex Tablet and Sonidegib will enhance the amount of Sonidegib, which increases the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Sonidegib and Solonex Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Solonex Tablet:
Combining Solonex Tablet with Citalopram may raise Citalopram blood levels and increase the chance of certain adverse effects, including an abnormal heart rhythm.

How to manage the interaction:
Although taking Solonex Tablet and Citalopram together can cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like a fast or pounding heartbeat, feeling dizzy or lightheaded, or having trouble breathing, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Solonex Tablet:
Co-administration of Solonex Tablet may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and Solonex Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Solonex Tablet:
When Omeprazole is taken with Solonex Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Omeprazole with Solonex Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks

Drug-Food Interactions

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ISONIAZID-300MGCaffeine containing foods/drinks
Common Foods to Avoid:
Dark Chocolate, Cocoa, Coffee, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine containing products including chocolates(which contains caffeine) during Solonex Tablet treatment may lead to an interaction. Avoid caffiene and its products during treatment with Solonex Tablet.

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Solonex Tablet Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Solonex Tablet contains isoniazid, an antibiotic used to treat and prevent tuberculosis. Solonex Tablet prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, Solonex Tablet may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

It is not recommended to take Solonex Tablet with food. You are advised to take Solonex Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal for better absorption.

You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer as they may interact with Solonex Tablet and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.

Yes, Solonex Tablet may cause liver problems in some patients. However, please consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may monitor your liver function while on treatment with Solonex Tablet .

You are advised to consult a doctor before taking phenytoin with Solonex Tablet as taking these medicines together may increase the levels of phenytoin in the blood and cause toxic effects. However, if you experience dizziness, vomiting, confusion or nausea, please consult your doctor.

Please do not stop taking Solonex Tablet suddenly without consulting your doctor as it may cause withdrawal symptoms such as irritation, nervousness, difficulty in sleeping, headache or having more dreams. Therefore, take Solonex Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Solonex Tablet , please consult your doctor.

Solonex Tablet is not recommended for patients suffering from fits as it may increase the risk of recurring fits. Therefore, it is advised to inform your doctor if you have a history of fits before taking Solonex Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking Solonex Tablet to monitor your liver function.
  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.
  • A monthly liver function test is advisable while using Solonex Tablet .

 

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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