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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET belongs to the group of medicines called anti-tubercular agents primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. SOLONEX DT 100MG TABLET does not work against infections caused by the virus.

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, SOLONEX DT 100MG TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take SOLONEX DT 100MG TABLET as prescribed. Use SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of SOLONEX DT 100MG TABLET. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If you are allergic to SOLONEX DT 100MG TABLET or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET.  Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while on treatment with SOLONEX DT 100MG TABLET as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ISONIAZID-100MG

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd.

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of SOLONEX DT 100MG TABLET

Tuberculosis (TB)

Medicinal Benefits

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Side Effects of SOLONEX DT 100MG TABLET

  • Fever
  • Dizziness
  • Nausea
  • Stomach upset
  • Loss of appetite
  • Constipation
  • Tiredness
  • Numbness or tingling in the feet or hands

Directions for Use

Take SOLONEX DT 100MG TABLET on an empty stomach at least one hour before or two hours after a meal or as advised by your doctor. Do not take it with food. Tablet: Swallow it as a whole with a glass of water. Do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to SOLONEX DT 100MG TABLET, please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET. Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking SOLONEX DT 100MG TABLET as they might cause drug-food interaction. Avoid alcohol consumption with SOLONEX DT 100MG TABLET as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
IsoniazidLovastatin
Critical

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
How does the drug interact with SOLONEX DT 100MG TABLET:
When Lomitapide is taken with SOLONEX DT 100MG TABLET, SOLONEX DT 100MG TABLET may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking SOLONEX DT 100MG TABLET with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidLovastatin
Critical
How does the drug interact with SOLONEX DT 100MG TABLET:
When Lovastatin is taken with SOLONEX DT 100MG TABLET, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking SOLONEX DT 100MG TABLET with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidRegorafenib
Critical
How does the drug interact with SOLONEX DT 100MG TABLET:
When SOLONEX DT 100MG TABLET is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with SOLONEX DT 100MG TABLET is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidAlfuzosin
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
Co-administration of SOLONEX DT 100MG TABLET will enhance the amount or action of alfuzosin when taken together.

How to manage the interaction:
Although taking SOLONEX DT 100MG TABLET with Alfuzosin together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
IsoniazidTizanidine
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
Co-administration of SOLONEX DT 100MG TABLET may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and SOLONEX DT 100MG TABLET, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.
IsoniazidHalothane
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
When Halothane is taken with SOLONEX DT 100MG TABLET, can increase the side affects of liver.

How to manage the interaction:
Co-administration of SOLONEX DT 100MG TABLET with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidSimvastatin
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
The combined use of SOLONEX DT 100MG TABLET and Simvastatin will enhance the levels of Simvastatin, which increases the risk of side effects.

How to manage the interaction:
Co-administration of Simvastatin and SOLONEX DT 100MG TABLET can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
IsoniazidSonidegib
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
The combined use of SOLONEX DT 100MG TABLET and Sonidegib will enhance the amount of Sonidegib, which increases the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Sonidegib and SOLONEX DT 100MG TABLET, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
IsoniazidCitalopram
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
Combining SOLONEX DT 100MG TABLET with Citalopram may raise Citalopram blood levels and increase the chance of certain adverse effects, including an abnormal heart rhythm.

How to manage the interaction:
Although taking SOLONEX DT 100MG TABLET and Citalopram together can cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like a fast or pounding heartbeat, feeling dizzy or lightheaded, or having trouble breathing, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
IsoniazidGlimepiride
Severe
How does the drug interact with SOLONEX DT 100MG TABLET:
Co-administration of Glimepiride with SOLONEX DT 100MG TABLET may interfere with blood glucose control and reduce the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with SOLONEX DT 100MG TABLET if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking SOLONEX DT 100MG TABLET to monitor your liver function.
  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.
  • A monthly liver function test is advisable while using SOLONEX DT 100MG TABLET.

 

Author Details

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Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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