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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

ISOTRETINOIN-20MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sotret 20 mg Capsule

Sotret 20 mg Capsule belongs to a class of drugs called retinoids (a synthetic form of vitamin A) primarily used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics. Nodular acne is severe acne that occurs due to excessive production of oil in the skin cells, causing swollen, red and tender lumps in the skin. Acne nodules are larger in size than typical pimples. 

Sotret 20 mg Capsule contains 'isotretinoin', a form of vitamin A that works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocks pores and kills acne-causing bacteria.

Take Sotret 20 mg Capsule as prescribed. Your doctor will advise you on how often you need to take Sotret 20 mg Capsule based on your medical condition. Some people may experience chapped lips, dryness of skin, eyes, nose, or lips. Most of these side effects of Sotret 20 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Sotret 20 mg Capsule or any other medicines, please tell your doctor. Do not take Sotret 20 mg Capsule if you are pregnant or breastfeeding as it may cause adverse effects on the baby. If you have depression or any suicidal thoughts while taking Sotret 20 mg Capsule or after stopping treatment with Sotret 20 mg Capsule , please consult a doctor. Avoid sun exposure while using Sotret 20 mg Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Uses of Sotret 20 mg Capsule

Nodular acne

Directions for Use

Take Sotret 20 mg Capsule with food or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Sotret 20 mg Capsule is a synthetic form of vitamin A used to treat a severe form of acne. Sotret 20 mg Capsule reduces sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocking pores and killing acne-causing bacteria. Also, Sotret 20 mg Capsule reduces swelling in the skin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sotret 20 mg Capsule
  • Exercise and a healthy diet can help manage high cholesterol, but consult your doctor about medication if lifestyle changes are not enough.
  • Avoid foods high in cholesterol, saturated fat, and trans fats, such as egg yolks, cheese, fried foods, pastries, ice cream, and red meat.
  • Increase your intake of vegetables, fruits, oats, whole grains, lentils, and beans to boost fibre consumption.
  • Include foods rich in monounsaturated fats, like nuts, avocados, olive oil, and oily fish.
  • Exercise regularly for 30 minutes and maintain a healthy weight.
  • Quit smoking and limit excessive alcohol consumption, as both can negatively impact your cholesterol levels.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
Managing Medication-Triggered Cheilitis (Inflammation of the lips): A Step-by-Step Guide:
  • Consult your doctor if you experience lip inflammation, redness, or irritation after taking medication.
  • Your doctor will assess your condition, investigate possible causes, and design a treatment plan.
  • To soothe and moisturize the lips, use topical creams or ointments like petroleum jelly or lip balm.
  • Practice good lip care by keeping your lips clean, avoiding irritants, and staying hydrated.
  • If your condition worsens or persists, speak with your doctor about further therapy.
  • If you notice increased red blood cell sedimentation rate (ESR) after starting a medication, consult your doctor so that they may advise possible medication adjustments.
  • Regular blood tests are advised to monitor your ESR levels to assess the effectiveness of any treatment plan.
  • Eat a well-balanced diet rich in nutrients and antioxidants to reduce inflammation.
  • Drink lots of water to maintain proper blood viscosity.
  • Do regular physical activity as it helps to manage chronic conditions that may contribute to high ESR.
  • If you a smoker, quit smoking as it can negatively impact ESR levels.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
  • Apply a gentle lip balm with ingredients such as castor seed oil or shea butter.
  • Ensure you are hydrated by drinking plenty of water; this helps heal your lips.
  • Avoid licking your lips or picking at them.
  • Use a humidifier at home, particularly at night, to maintain moisture in the air.
  • Protect your lips from sun exposure by using SPF lip balm and avoid using any irritating components.
  • Stay away from metal objects that could irritate your lips.
  • Consume a vitamin-rich diet to enhance the health of your skin overall.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.

Drug Warnings

Do not take Sotret 20 mg Capsule if you are pregnant or breastfeeding as it may cause adverse effects in the baby. If you have depression or any suicidal thoughts while taking Sotret 20 mg Capsule or after stopping treatment with Sotret 20 mg Capsule , please consult a doctor. Avoid sun exposure while using Sotret 20 mg Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not undergo any cosmetic procedures while taking Sotret 20 mg Capsule and for a minimum of 6 months after stopping treatment with Sotret 20 mg Capsule as it may increase the risk of scarring. Inform your doctor if you have asthma, diabetes, hypervitaminosis A (high levels of vitamin A), liver or heart problems, weak bones, osteoporosis (bone loss), anorexia nervosa (an eating disorder where people eat too little), any mental problems such as psychosis (loss of contact with reality) or depression before taking Sotret 20 mg Capsule .

Drug-Drug Interactions

verifiedApollotooltip
IsotretinoinDoxycycline
Critical
IsotretinoinOxytetracycline
Critical

Drug-Drug Interactions

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IsotretinoinDoxycycline
Critical
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with Doxycycline may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Sotret 20 mg Capsule and Doxycycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinOxytetracycline
Critical
How does the drug interact with Sotret 20 mg Capsule:
Co-administration of Sotret 20 mg Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Sotret 20 mg Capsule and Oxytetracycline together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinDemeclocycline
Critical
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with Demeclocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Sotret 20 mg Capsule and Demeclocycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinMinocycline
Severe
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with minocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Sotret 20 mg Capsule and minocycline together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting a doctor.
IsotretinoinLomitapide
Severe
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with lomitapide may affect liver and cause liver problems.

How to manage the interaction:
Although taking Sotret 20 mg Capsule and lomitapide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
IsotretinoinTretinoin
Severe
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule together with tretinoin may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking Sotret 20 mg Capsule and tretinoin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.
IsotretinoinTeriflunomide
Severe
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with teriflunomide may affect liver and causes liver problems.

How to manage the interaction:
Although taking Sotret 20 mg Capsule and teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting doctor.
IsotretinoinAminolevulinic acid
Severe
How does the drug interact with Sotret 20 mg Capsule:
Taking Sotret 20 mg Capsule with aminolevulinic acid may increase the risk of a severe sunburn.

How to manage the interaction:
Although taking Sotret 20 mg Capsule and aminolevulinic acid together can possibly result in an interaction, it can be taken if your doctor has prescribed it. After taking you should avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Incase you experience any unusual symptoms, consult a doctor. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regular exercise can improve your mood and self-esteem though it doesn't clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Avoid sun exposure while using Sotret 20 mg Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Do regular hair wash and avoid contact of hair with the face.
  • Remove the make-up completely before going to bed.

Habit Forming

No

Therapeutic Class

RETINOIDS

Sotret 20 mg Capsule Substitute

Substitutes safety advice
  • Isotroin-20 Softgel Capsule 15's

    by AYUR

    29.54per tablet
  • Acutret 20 Capsule 10's

    by Others

    27.18per tablet
  • Tretiva-20 Capsule 10's

    by Others

    23.40per tablet
  • Tretin-Iso 20 Capsule 10's

    by Others

    27.90per tablet
  • Zitblow 20 Capsule 10's

    by AYUR

    29.70per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sotret 20 mg Capsule may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.

No, you are not recommended to undergo any cosmetic procedures to smoothen your skin including waxing, laser procedures or dermabrasion (an exfoliating technique to remove outer layers of skin with a rotating instrument) while taking Sotret 20 mg Capsule and for minimum 6 months after stopping treatment with Sotret 20 mg Capsule as it may increase the risk of scarring.

You are not recommended to take vitamin A supplements with Sotret 20 mg Capsule as it may cause hypervitaminosis A (excessive levels of vitamin A in the body) leading to an increased risk of adverse effects. However, please consult a doctor before taking other medicines or supplements with Sotret 20 mg Capsule .

No, Sotret 20 mg Capsule is not recommended for use during pregnancy as it may cause severe birth defects. Also, it is advised to use effective contraceptive measures before, while taking Sotret 20 mg Capsule and after 1 month of stopping treatment with Sotret 20 mg Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Sotret 20 mg Capsule .

Sotret 20 mg Capsule may cause decreased night vision temporarily or permanently in some patients. It is not necessary for everyone taking Sotret 20 mg Capsule to experience this side effect. Avoid driving after taking Sotret 20 mg Capsule if you are unable to see in the dark and consult a doctor if you notice any changes in vision or have painful or persistent dry eyes.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • DOXYCYCLINE
  • TETRACYCLINE
  • DEMECLOCYCLINE
  • MINOCYCLINE
  • OXYTETRACYCLINE
  • ERAVACYCLINE
  • VITAMIN A

Special Advise

  • Regular blood tests are recommended before and while taking Sotret 20 mg Capsule to monitor liver functioning.
  • Do not donate blood while taking Sotret 20 mg Capsule and for one month after stopping Sotret 20 mg Capsule .
  • Do not squeeze, pop or pick spots as it may worsen them and cause permanent scarring.

Disease/Condition Glossary

Nodular acne: It is severe acne that occurs due to excessive production of oil in the skin cells causing swollen, red and tender lumps in the skin which can be the size of pencil erasers or larger. The sebum inhibits sebaceous glands and stops oil from flowing out freely causing accumulation of sebum under the skin which increases the growth of acne-causing bacteria. Acne nodules are larger in size than typical pimples and affect the deeper layers of skin. Nodular acne can occur on the back, face and the body. If they are left untreated, it may cause permanent scars. The symptoms include long-lasting painful blemishes that feel like hard knots under the skin.

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