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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Apex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Spanil 50mg/325mg Tablet

Spanil 50mg/325mg Tablet belongs to a class of medications known as a non-steroidal anti-inflammatory drug (NSAID) or pain killer. Spanil 50mg/325mg Tablet is widely useful for treating painful musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Spanil 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

Spanil 50mg/325mg Tablet can be taken with or after the meal. Spanil 50mg/325mg Tablet may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritis (itchy skin), and rash, although not everybody gets them. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

Spanil 50mg/325mg Tablet is not recommended during the last three months of pregnancy and for children. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects/interactions. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Uses of Spanil 50mg/325mg Tablet

Pain relief (Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Spanil 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Spanil 50mg/325mg Tablet if you are allergic to any components present in it. Patients with asthma, prolonged bleeding time, wheezing (whistling sound during breath), and blocked airways (bronchospasm) should avoid using Spanil 50mg/325mg Tablet. It is not recommended for use in children less than 14 years of age, people with liver disease, heart disease, or gastric ulcers/bleeding problems. Spanil 50mg/325mg Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Pregnant women should not take during their last trimester of pregnancy. Spanil 50mg/325mg Tablet is excreted in the breast milk, so the nursing mother should contact the doctor before its usage. Avoid the consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Spanil 50mg/325mg Tablet:
Co-administration of Spanil 50mg/325mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Spanil 50mg/325mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Spanil 50mg/325mg Tablet:
Co-administration use of Spanil 50mg/325mg Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Spanil 50mg/325mg Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Spanil 50mg/325mg Tablet:
Co-administration of Spanil 50mg/325mg Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Spanil 50mg/325mg Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Taking Spanil 50mg/325mg Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Spanil 50mg/325mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Coadministration of Spanil 50mg/325mg Tablet and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Spanil 50mg/325mg Tablet and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacMipomersen
Severe
How does the drug interact with Spanil 50mg/325mg Tablet:
Co-administration of Spanil 50mg/325mg Tablet with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Spanil 50mg/325mg Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Coadministration of Spanil 50mg/325mg Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Spanil 50mg/325mg Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Coadministration of Spanil 50mg/325mg Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Spanil 50mg/325mg Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Taking amiloride with Spanil 50mg/325mg Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Spanil 50mg/325mg Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Spanil 50mg/325mg Tablet:
Co-administration of Spanil 50mg/325mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Spanil 50mg/325mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Spanil 50mg/325mg Tablet contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action.

No, Spanil 50mg/325mg Tablet is not indicated for stomach pain. Also, If you have stomach pain post-ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Spanil 50mg/325mg Tablet in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.

No, do not take Spanil 50mg/325mg Tablet until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen, or gallbladder problems. Your back pain may be due to kidney stones, pancreas swelling, or, in women, pelvic disorders. Your arm pain (especially the left arm) may be due to a heart attack (myocardial infarction).

Yes, Spanil 50mg/325mg Tablet is a short-term medication, and if you feel better, you can stop taking Spanil 50mg/325mg Tablet, but only after consulting your doctor.

Yes, the long-term use of Spanil 50mg/325mg Tablet can cause damage to the kidneys.

No, Spanil 50mg/325mg Tablet is not addictive, but it's important always to take it as prescribed.

No, Spanil 50mg/325mg Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results of Spanil 50mg/325mg Tablet, take it in doses and duration mentioned by your doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CIPROFLOXACIN
  • FUROSEMIDE
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LEVOFLOXACIN
  • MOXIFLOXACIN
  • NALIDIXIC ACID
  • NORFLOXACIN
  • OFLOXACIN
  • BUMETANIDE
  • DIGOXIN
  • COLESTIPOL
  • CHOLESTYRAMINE
  • PHENYTOIN
  • CICLOSPORIN
  • TACROLIMUS
  • HYDROCORTISONE
  • PREDNISOLONE
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.

Musculoskeletal pain: It is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports-related) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused due to sprains, strains, trauma, or post-surgery may require prolonged healing time.

Osteoarthritis: Osteoarthritis is the most common form of joint disorder, which occurs when the protective cartilage that cushions the ends of your bones wears down over time. It can damage any joint, affecting your hands, knees, hips and spine joints.

Ankylosing spondylitis: Ankylosing spondylitis is the painful condition in which fused bones of your spinal cord or vertebrae gets inflamed, leading to hunched spine. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

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