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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Last Updated Aug 20, 2024 | 12:53 PM IST

About Spd Plus Tablet 10's

Spd Plus Tablet 10's belongs to the class of combination medication called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints which causes pain and joint stiffness.

Spd Plus Tablet 10's is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent thereby decreasing swelling at the painful site. 
 
You are advised to take Spd Plus Tablet 10's for as long as your doctor has prescribed it for you. In some cases, Spd Plus Tablet 10's may cause certain common side-effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Spd Plus Tablet 10's may cause drowsiness and dizziness, so drive with caution. Spd Plus Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Spd Plus Tablet 10's as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Spd Plus Tablet 10's

Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Medicinal Benefits

Spd Plus Tablet 10's is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Spd Plus Tablet 10's is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Spd Plus Tablet 10's increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reduces inflammation. 

Directions for Use

Take Spd Plus Tablet 10's with food. Swallow Spd Plus Tablet 10's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Spd Plus Tablet 10's

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

Drug Warnings

Do not take Spd Plus Tablet 10's if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Spd Plus Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Spd Plus Tablet 10's is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Spd Plus Tablet 10's as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Spd Plus Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Spd Plus Tablet 10's unless prescribed.

Drug Interactions

Drug-Drug Interactions: Spd Plus Tablet 10's may interact with pain killers (aspirin, ibuprofen), immunosuppressants (cyclosporine, tacrolimus), anti-psychotic (lithium), cardiac glycoside (digoxin), blood thinner (warfarin), anti-rheumatoid (methotrexate), antacid (magnesium hydroxide), anti-fungal (ketoconazole, miconazole, fluconazole, voriconazole), anti-arrhythmic (amiodarone), anti-gout (sulfinpyrazone), anti-emetic (metoclopramide, domperidone), bile acid sequestrant (cholestyramine), anti-cancer (imatinib), antibiotic (chloramphenicol), anti-progestational steroid (mifepristone), anti-diabetics, diuretics, anti-hypertensives medicines.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, inflammation of intestines, anaemia, heart, kidney or liver problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CYCLOSPORINE
  • TACROLIMUS
  • LITHIUM
  • DIGOXIN
  • WARFARIN
  • METHOTREXATE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • MICONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • AMIDODARONE
  • SULFINPYRAZONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • CHLORAMPHENICOL
  • MIFEPRESTONE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

About Spd Plus Tablet 10's

Spd Plus Tablet 10's belongs to the class of combination medication called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints which causes pain and joint stiffness.

Spd Plus Tablet 10's is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent thereby decreasing swelling at the painful site. 
 
You are advised to take Spd Plus Tablet 10's for as long as your doctor has prescribed it for you. In some cases, Spd Plus Tablet 10's may cause certain common side-effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Spd Plus Tablet 10's may cause drowsiness and dizziness, so drive with caution. Spd Plus Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Spd Plus Tablet 10's as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Spd Plus Tablet 10's

Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Medicinal Benefits

Spd Plus Tablet 10's is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Spd Plus Tablet 10's is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Spd Plus Tablet 10's increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reduces inflammation. 

Side Effects of Spd Plus Tablet 10's

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

Directions for Use

Take Spd Plus Tablet 10's with food. Swallow Spd Plus Tablet 10's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Spd Plus Tablet 10's if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Spd Plus Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Spd Plus Tablet 10's is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Spd Plus Tablet 10's as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Spd Plus Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Spd Plus Tablet 10's unless prescribed.

Therapeutic Class

ANALGESICS

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CYCLOSPORINE
  • TACROLIMUS
  • LITHIUM
  • DIGOXIN
  • WARFARIN
  • METHOTREXATE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • MICONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • AMIDODARONE
  • SULFINPYRAZONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • CHLORAMPHENICOL
  • MIFEPRESTONE

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

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