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  3. Spye Tablet 10's

Spye Tablet 10's, Pack of 10 TABLETS
Spye Tablet 10's, Pack of 10 TABLETS
Spye Tablet 10's, Pack of 10 TABLETS
Spye Tablet 10's, Pack of 10 TABLETS
Spye Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Whats That

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Composition :

SPIRAMYCIN-3MIU

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Spye Tablet

Spye Tablet belongs to a group of medicines known as macrolide antibiotics primarily used to treat cryptosporidiosis (a diarrheal disease caused by microscopic parasites, cryptosporidium), susceptible infections, and soft tissue infections. It is also used to treat a parasitic infection known as toxoplasmosis in pregnant women. It helps to lower the risk of transmission of toxoplasma infection from the mother to the unborn child. A bacterial infection is a condition in which bacteria grows in the body and causes infection. It can target any body part and multiple very quickly. Toxoplasmosis infection can cause complications such as miscarriage, stillbirth, and damage to a baby’s brain and other organs, particularly the eyes, at birth or early childhood, or even as adults with a weak immune system.

Spye Tablet contains ‘Spiramycin,’ an antibiotic that treats bacterial infections of the abdomen, bone, skin, heart, and soft tissues. It may also be used to reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. Spye Tablet works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial and parasitic reproduction but doesn't kill them. 

Take Spye Tablet as prescribed by your doctor. You are advised to take Spye Tablet for the duration as prescribed, depending on your medical condition. Spye Tablet causes side effects in some people. Common side effects of Spye Tablet include stomach pain, nausea, vomiting, and diarrhea. Most of these side effects of Spye Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Spye Tablet or any other medicines, please tell your doctor. Do not use Spye Tablet while having vaccinations with live bacterial vaccines (typhoid vaccine) since Spye Tablet may affect the vaccine's activity. Spye Tablet should be used only with a doctor's advice during pregnancy and breastfeeding. Do not give this medicine to your child without medical advice. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare genetic blood disorder), or electrolyte imbalance (low potassium or magnesium level).

Uses of Spye Tablet

Bacterial infections, Toxoplasmosis during pregnancy

Directions for Use

Swallow the capsule as a whole with a glass of water with or without food. Do not chew, crush, or break it.

Medicinal Benefits

Spye Tablet contains ‘Spiramycin’ as an antibiotic that treats bacterial infections like various infections of the abdomen, bone, skin, heart and soft tissues. It may also reduce the risk of a serious parasite infection (toxoplasmosis) spreading to an unborn baby during pregnancy. Spye Tablet works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Spye Tablet effectively treats infections caused by gram-positive and aerobic (living with air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumonia, N. gonorrhoea,  gram-negative bacteria, and cryptosporidium spices. Spye Tablet treats serious infections caused by susceptible aerobic bacteria in the abdomen, gastrointestinal tract, lower respiratory tract, skin, and in genitourinary area. It will not work for viral infections (such as the common cold or flu).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Spye Tablet if you are allergic to Spye Tablet or its components. Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), porphyria (rare inherited blood disorders), or electrolyte imbalance (low potassium or magnesium level). Regular monitoring of liver function tests may be required while using Spye Tablet . In rare cases, the use of Spye Tablet can cause diarrhoea, so in case you have watery or bloody diarrhoea, stop taking Spye Tablet and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you.  Spye Tablet is safe to use during pregnancy. However, please consult your doctor if you are pregnant, planning for pregnancy, or breastfeeding before using Spye Tablet . It should be taken by the children only if the doctor has prescribed it. In some cases, Spye Tablet may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause fast/irregular heartbeat and other symptoms (such as severe dizziness and fainting) that need medical attention immediately. Elderly adults may be more sensitive to the side effects of Spye Tablet , especially QT prolongation. Spye Tablet may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to. Do not skip the doses and finish the full course of treatment even if you feel better. Stopping the Spye Tablet too early may lead to the infection returning or worsening.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking a full course of Spye Tablet in order to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine. 

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Avoid taking too much calcium, iron-enriched foods, and drinks as it might affect the working of Spye Tablet . 

  • Avoid intake of alcoholic beverages with Spye Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Spye Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Spye Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:34 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Spye Tablet contains Spiramycin' which works by preventing the synthesis of essential proteins required by bacteria and parasites to carry out vital functions. Thus, it stops the bacteria or parasite's growth and prevents the infection from spreading.

You are not recommended to use Spye Tablet with amiodarone (a medicine used to treat abnormal heart rhythm) simultaneously as it may affect the heart rhythm (QT prolongation). QT prolongation can rarely cause serious and sometimes fatal fast/irregular heartbeat and other symptoms (such as severe dizziness and fainting) that need immediate medical attention. However, please consult a doctor before using Spye Tablet with any other medicines.

Spye Tablet can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Spye Tablet if you are undergoing any vaccinations.

Do not use anti diarrhoeal until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea, as it may help increase the number of good bacteria in the intestine, which aids in digestion.

In some cases, people using Spye Tablet may have a fungal infection called thrush after taking its full course. It happens because antibiotics also kill the harmless bacteria that protect against thrush.

No. You should complete the full course of Spye Tablet as your doctor prescribes. Take Spye Tablet at the right dose, times, and for the right number of days.

Drug-Drug Interactions Checker List

  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • AMIDODARONE
  • DOFETILIDE
  • PIMOZIDE
  • PROCAINAMIDE
  • QUINIDINE
  • ERYTHROMYCIN

Special Advise

  • Liver function monitoring (liver function tests) is recommended in patients with severe liver disease.

  • Spye Tablet may cause Clostridium difficile-associated diarrhea (CDAD); hence it is advised to undergo regular gastrointestinal screening.

Disease/Condition Glossary

A bacterial infection:  It is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

Toxoplasmosis: is an infection caused by parasites toxoplasma gondii found in contaminated food and cat feces. It can cause serious complications for pregnant women, such as miscarriage, stillbirths, and damage to the baby’s brain and other organs, particularly the eyes, at birth or early childhood, and people with weakened immune systems. Symptoms include muscle pain, fever, headache, etc.

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