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Written By ,
Reviewed By Sunny S , MBBS

About STRESNIL 0.25MG TABLET

STRESNIL 0.25MG TABLET belongs to a class of medication called sedatives and hypnotics, primarily used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. Insomnia is a sleeping disorder in which a person finds difficulty in falling asleep or staying asleep. Due to anxiety and panic disorder, a person cannot sleep due to disturbances in their circadian cycle and hormonal imbalance in the brain like melatonin. 

STRESNIL 0.25MG TABLET is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime. 

Take STRESNIL 0.25MG TABLET with or without food and swallow whole with a glass of water. Do not break, crush, or chew it. Your doctor will advise you how often you take STRESNIL 0.25MG TABLET based on your medical condition. The most common side effects of STRESNIL 0.25MG TABLET include drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of STRESNIL 0.25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tell your doctor if you have an ongoing medical condition, including depression, diabetes, an autoimmune disorder, or high blood pressure. If you are known to be allergic to STRESNIL 0.25MG TABLET or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking STRESNIL 0.25MG TABLET. STRESNIL 0.25MG TABLET should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Aristo Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of STRESNIL 0.25MG TABLET

Insomnia (sleeplessness) 

Medicinal Benefits

STRESNIL 0.25MG TABLET belongs to a class of sedatives and hypnotics, primarily used to treat insomnia (difficulty in falling asleep or staying asleep). STRESNIL 0.25MG TABLET is a combination of two medicines: 'Alprazolam' and  'Melatonin', which helps a person fall asleep faster and stay asleep during the night, which has been disturbed due to anxiety or panic disorder. STRESNIL 0.25MG TABLET helps relax the brain's exciting chemicals (GABA), allowing a person to sleep easily and stay asleep during the whole night without any disturbance.  

Side Effects of STRESNIL 0.25MG TABLET

  • Tiredness
  • Dizziness
  • Headache
  • Drowsiness
  • Stomach pain
  • Depressed mood

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before your doctor prescribes your STRESNIL 0.25MG TABLET, you should tell your doctor if you have allergies or not. With it, also tell if you are pregnant or breastfeeding as the use of this medication is restricted to be used in pregnancy and breastfeeding. Elderly people are more responsive to the side effects of the drug, so they should tell every product, including the herbal ones to their doctor so that doctor can decide the dosage for them. Inform your doctor about myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, and kidney/liver problem before taking STRESNIL 0.25MG TABLET. Do not take STRESNIL 0.25MG TABLET with opioids as it may cause breathing problems, drowsiness and coma.

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
AlprazolamCobicistat
Critical

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Co-administration of Stresnil 0.25 mg Tablet 10's with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Stresnil 0.25 mg Tablet 10's and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Co-administration of Stresnil 0.25 mg Tablet 10's with Cobicistat may considerably increase the blood levels and effects of Stresnil 0.25 mg Tablet 10's.

How to manage the interaction:
Despite the fact that there is an interaction between Stresnil 0.25 mg Tablet 10's and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamDelavirdine
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
The combination of Stresnil 0.25 mg Tablet 10's and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Stresnil 0.25 mg Tablet 10's and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamIndinavir
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
The combination of Stresnil 0.25 mg Tablet 10's and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Stresnil 0.25 mg Tablet 10's and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamKetoconazole
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Co-administration of Stresnil 0.25 mg Tablet 10's with Ketoconazole may considerably increase the blood levels of Stresnil 0.25 mg Tablet 10's, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Stresnil 0.25 mg Tablet 10's and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamItraconazole
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Stresnil 0.25 mg Tablet 10's's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Stresnil 0.25 mg Tablet 10's and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamClarithromycin
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
The combination of Stresnil 0.25 mg Tablet 10's and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Stresnil 0.25 mg Tablet 10's and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamCeritinib
Critical
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Co-administration of Stresnil 0.25 mg Tablet 10's with Ceritinib may considerably increase the blood levels and effects of Stresnil 0.25 mg Tablet 10's.

How to manage the interaction:
Although there is a interaction between Stresnil 0.25 mg Tablet 10's and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamPentazocine
Severe
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Taking Stresnil 0.25 mg Tablet 10's with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is an interaction between Stresnil 0.25 mg Tablet 10's and Pentazocine, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, sleepiness, or difficulty concentrating. Do not discontinue any medications without consulting a doctor.
AlprazolamKetamine
Severe
How does the drug interact with Stresnil 0.25 mg Tablet 10's:
Using Stresnil 0.25 mg Tablet 10's together with Ketamine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Stresnil 0.25 mg Tablet 10's and Ketamine may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUOXETINE
  • NEFAZODONE
  • ERYTHROMYCIN
  • RIFABUTIN
  • KETOCONAZOLE
  • MORPHINE
  • CODEINE
  • DIHYDROCODEINE
  • BUPRENORPHINE

Diet & Lifestyle Advise

  • Keeping a fixed time to go to bed and wake up consistently every day helps maintain a better sleeping and waking plan.
  • Engage yourself in workouts, dancing, and walking that help promote calmness in the body so that you can enjoy a good night's sleep.
  • Taking naps in a day can make it harder to fall asleep at night, so one should try to limit a nap to no more than half an hour and don't nap after 2 p.m. 
  • Limit caffeine and alcohol consumption as it will not let you sleep and causes frequent urination.
  • Avoid large, heavy meals before bed. One can have a light snack that helps to avoid heartburn.
  • Avoid consumption of alcohol as it may increase drowsiness.
  • Take less liquid before bedtime so that you won't have to urinate as often. One must keep their worries and planning aside and enjoy a warm bath or a massage before bedtime. It will help in having a good night's relaxing sleep.

Habit Forming

Yes

Special Advise

  • Do not take STRESNIL 0.25MG TABLET for a prolonged time as it may lead to mental or physical dependence on STRESNIL 0.25MG TABLET.

Disease/Condition Glossary

Insomnia: It is a sleep disorder that affects many people in the world. Persons dealing with insomnia don't feel energetic or refreshed after waking up from a long night's sleep. It is of two types: Acute and chronic insomnia. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months, making a person either wake up the whole night or cause trouble in falling asleep. Causes of insomnia include stress, physical pain, any traumatic event, psychological issues including depression, diabetes, side effects of certain medications, and many more. Signs and symptoms of insomnia include fatigue, irritability, trouble concentrating on tasks, and mood changes.

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