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  3. SUDOPEN 500MG INJECTION

SUDOPEN 500MG INJECTION, Pack of 1 INJECTION
Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

DORIPENEM-500MG

Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About SUDOPEN 500MG INJECTION

SUDOPEN 500MG INJECTION belongs to the group of antibiotic medicines called carbapenems. It is indicated in treating bacterial infections such as complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis). Bacterial infections are illnesses or conditions caused by bacterial growth or toxins (poisons).

SUDOPEN 500MG INJECTION contains doripenem. Doripenem is an antibacterial drug. It works by inhibiting bacterial enzymes called penicillin-binding proteins (PBPs) and shows a bactericidal effect. Thus, SUDOPEN 500MG INJECTION treats bacterial infections.

SUDOPEN 500MG INJECTION will be administered by a healthcare professional; do not self-administer. Sometimes, SUDOPEN 500MG INJECTION may cause injection site reactions, headaches, nausea, diarrhoea, rash, and phlebitis (vein inflammation). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, consult your doctor.

Inform your doctor if you are allergic to any component in SUDOPEN 500MG INJECTION. If you are pregnant or breastfeeding, inform your doctor before taking SUDOPEN 500MG INJECTION. It is not recommended for use in children below 18 as safety and effectiveness have not been established. Keep your doctor up to date on your medical condition and medications to rule out any potential adverse effects or interactions.

Uses of SUDOPEN 500MG INJECTION

Bacterial infections (Complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis).

Directions for Use

A healthcare professional will administer SUDOPEN 500MG INJECTION. Do not self-administer.

Medicinal Benefits

SUDOPEN 500MG INJECTION contains doripenem. Doripenem is an antibacterial drug. It works by killing bacteria. Thus, SUDOPEN 500MG INJECTION helps treat bacterial infections. It is indicated in treating bacterial infections such as complicated intra-abdominal infections and complicated urinary tract infections (including pyelonephritis).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

SUDOPEN 500MG INJECTION is contraindicated in patients with known serious hypersensitivity to doripenem, other drugs in the same class, or patients who have demonstrated anaphylactic reactions to beta-lactams. To reduce the development of drug-resistant bacteria and maintain the effectiveness of SUDOPEN 500MG INJECTION should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. If symptoms worsen or persist or new symptoms appear, patients should stop using the medicine and consult a doctor. Valproic acid lowers serum valproic acid concentrations. Patients with seizure disorders treated with valproic acid or sodium valproate are at a higher risk of having a seizure.

Drug-Drug Interactions

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DoripenemSodium Valproate
Severe
DoripenemDivalproex
Severe

Drug-Drug Interactions

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DoripenemSodium Valproate
Severe
How does the drug interact with Sudopen 500mg Injection:
Co-administration of sodium valproate with Sudopen 500mg Injection can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and sodium valproate can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DoripenemDivalproex
Severe
How does the drug interact with Sudopen 500mg Injection:
Co-administration of Divalproex and Sudopen 500mg Injection can reduce the blood levels of divalproex sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Divalproex with Sudopen 500mg Injection can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of SUDOPEN 500MG INJECTION to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of SUDOPEN 500MG INJECTION.
  • Avoid intake of alcoholic beverages with SUDOPEN 500MG INJECTION as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the SUDOPEN 500MG INJECTION in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

SUDOPEN 500MG INJECTION Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

SUDOPEN 500MG INJECTION contains doripenem. Doripenem is an antibacterial drug. It works by killing bacteria. Thus, SUDOPEN 500MG INJECTION helps treat bacterial infections.

Caution should be exercised. Patients with seizure disorders who are being treated with valproic acid or sodium valproate are at a higher risk of having a seizure. It has been demonstrated that administering SUDOPEN 500MG INJECTION together with valproic acid lowers its (valproic acid) serum levels.

In some cases, SUDOPEN 500MG INJECTION may lead to Clostridium difficile-associated diarrhoea (ranging from mild to fatal colitis): in major cases, it gradually resolves over time. In case this condition persists, consult your doctor immediately.

Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.

To reduce the development of antibiotic resistance and maintain the effectiveness of SUDOPEN 500MG INJECTION, it should only be used to treat or prevent infections that are proven or highly suspected to be caused by bacteria.

Usually, SUDOPEN 500MG INJECTION starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

Drug-Drug Interactions Checker List

  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • VALPROIC ACID
  • DIVALPROEX SODIUM

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, damaging tissue and making you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

Pyelonephritis: Pyelonephritis is caused by an ascending urinary tract infection that travels from the bladder to the kidneys. Fever, flank discomfort, nausea, vomiting, burning with urine, increased frequency, and urgency are common symptoms.

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