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  3. Sulpidon OD 400 Tablet 10's

Sulpidon OD 400 Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

AMISULPRIDE-400MG

Manufacturer/Marketer :

Arinna Lifesciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sulpidon OD 400 Tablet

Sulpidon OD 400 Tablet belongs to a group of medicines called 'antipsychotics' primarily used to treat long term (chronic) schizophrenia and postoperative nausea/vomiting. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). In schizophrenic disorders, there are positive symptoms (like delusions, hallucinations and thought disorders) along with negative symptoms (like blunted effect, emotional and social withdrawal). Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth.

Sulpidon OD 400 Tablet contains Amisulpride, which helps restore the balance of certain natural substances in the brain. The key action of Sulpidon OD 400 Tablet is to block some of the dopamine receptors in the brain and correct dopamine's overactivity. On the other hand, it also affects other brain neurotransmitters such as serotonin (5-HT), which may also lead to its beneficial effects. Sulpidon OD 400 Tablet also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

Sulpidon OD 400 Tablet can be taken with or without food as prescribed by your doctor. You are advised to take Sulpidon OD 400 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain side effects such as dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, increased prolactin level in blood. Most of these side effects of Sulpidon OD 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist for a longer duration, consult your doctor immediately.

Sulpidon OD 400 Tablet should be avoided if you are allergic to it or any other medicines. Sulpidon OD 400 Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, inform your doctor before taking Sulpidon OD 400 Tablet . Use Sulpidon OD 400 Tablet with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects.  If you have breast cancer, pheochromocytoma (tumor of the adrenal gland), pituitary gland prolactinoma (tumor of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking Sulpidon OD 400 Tablet . Avoid driving and op taking Sulpidon OD 400 Tablet as it may cause drowsiness or dizziness.

Uses of Sulpidon OD 400 Tablet

SchizophreniaPostoperative nausea and vomiting (PONV)

Directions for Use

Tablet: Take Sulpidon OD 400 Tablet with or without food as prescribed by your doctor. The doctor determines the dose and duration of the medicine. Swallow the medicines as a whole with a glass of water. Do not crush, chew or break it. Oral solution: The liquid form of Sulpidon OD 400 Tablet should be taken by mouth using the measuring cup provided by the pack, shake the bottle well before each use.

Medicinal Benefits

Sulpidon OD 400 Tablet contains Amisulpride, a group of medicines called antipsychotics used to treat a mental illness called schizophrenia, bipolar disorder. Additionally, Sulpidon OD 400 Tablet has anti-emetics properties used either monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. The key action of Sulpidon OD 400 Tablet is to block some of the brain's dopamine receptors and correct dopamine's overactivity, thereby producing a calming effect in the brain. Altogether, Sulpidon OD 400 Tablet may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Sulpidon OD 400 Tablet
  • Drink plenty of water throughout the day to maintain electrolyte balance and flush out toxins.
  • Include magnesium-rich foods like dark leafy greens, nuts, and seeds in your diet to help relax muscles.
  • Consume potassium-rich foods like bananas, avocados, and sweet potatoes and omega-3 fatty acids such as fatty fish, flaxseeds, and walnuts.
  • Engage in stress-reduction techniques such as meditation, deep breathing, or progressive muscle relaxation.
  • Aim for 7-8 hours of sleep per night to regulate muscle function and reduce symptoms.
  • Limit or avoid stimulants like caffeine, nicotine, and certain medications that may increase dystonic symptoms.
  • Use relaxation techniques like visualization, guided imagery, or mindfulness meditation to manage stress and reduce symptoms.
  • If you experience persistent involuntary muscle contractions, especially in the neck, tongue, or eyes, consult your doctor.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

  • Do not take Sulpidon OD 400 Tablet if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumor or breast cancer, phaeochromocytoma (a tumor on the adrenal gland), pituitary tumor.
  • Sulpidon OD 400 Tablet should not be given to children as safety has not been established.
  • Use Sulpidon OD 400 Tablet with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects.
  • If you are pregnant or breastfeeding, please consult a doctor before taking Sulpidon OD 400 Tablet . Sulpidon OD 400 Tablet may impair fertility, so inform your doctor if you are planning for pregnancy.
  • Inform your doctor if you are previously diagnosed with kidney disease, liver disease epilepsy or seizures (fits), Parkinson's disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem), if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder).
  • Sulpidon OD 400 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Sulpidon OD 400 Tablet as it could lead to increased drowsiness and dizziness.  

Drug-Drug Interactions

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AmisulpridePimozide
Critical
AmisulprideDronedarone
Critical

Drug-Drug Interactions

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AmisulpridePimozide
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Pimozide with Sulpidon OD 400 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Sulpidon OD 400 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideDronedarone
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Sulpidon OD 400 Tablet with Dronedarone can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideMesoridazine
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Sulpidon OD 400 Tablet with Mesoridazine can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Mesoridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideSaquinavir
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Saquinavir with Sulpidon OD 400 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideCisapride
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Sulpidon OD 400 Tablet with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideGrepafloxacin
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Sulpidon OD 400 Tablet with Grepafloxacin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Grepafloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
AmisulprideMetoclopramide
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Taking Metoclopramide with Sulpidon OD 400 Tablet may increase the risk or severity of side effects.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Metoclopramide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideZiprasidone
Critical
How does the drug interact with Sulpidon OD 400 Tablet:
Co-administration of Ziprasidone with Sulpidon OD 400 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Sulpidon OD 400 Tablet but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmisulprideHistrelin
Severe
How does the drug interact with Sulpidon OD 400 Tablet:
Using Sulpidon OD 400 Tablet together with histrelin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Histrelin together can result in an interaction, but it can be taken if a doctor has advised it. If you experience symptoms like an irregular heartbeat, dizziness, or shortness of breath, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
AmisulprideNorfloxacin
Severe
How does the drug interact with Sulpidon OD 400 Tablet:
Coadministration of Sulpidon OD 400 Tablet with Norfloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Sulpidon OD 400 Tablet with Norfloxacin together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Mental illness:

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. 
  • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
  • You may also practice calming techniques such as meditation and deep breathing exercises.
  • Get some normal sleep. Having enough sleep will help to stabilize your mood.
  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

 

Nausea/Vomiting:

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated. Use oral rehydration solutions (ORS) to replace lost electrolytes.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:37 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sulpidon OD 400 Tablet contains Amisulpride, which works by modulating certain chemical messengers (dopamine D2) in the brain, which helps regulate mood, behavior, nausea and vomiting.

Sulpidon OD 400 Tablet can be used to treat psychotic disorders like schizophrenia, bipolar disorder and depression. However, you should not take this medication without a doctor’s advice.

Sulpidon OD 400 Tablet may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood) resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.

You are not recommended to stop taking Sulpidon OD 400 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Sulpidon OD 400 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Sulpidon OD 400 Tablet , please consult your doctor so that the dose may be gradually reduced.

Sulpidon OD 400 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or history of stroke before taking Sulpidon OD 400 Tablet .

Stopping Sulpidon OD 400 Tablet abruptly can cause withdrawal symptoms and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Sulpidon OD 400 Tablet .

Take Sulpidon OD 400 Tablet with caution in patients with diabetes as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while taking Sulpidon OD 400 Tablet .

Drug-Drug Interactions Checker List

  • QUINIDINE
  • DISOPYRAMIDE
  • AMIODARONE
  • SOTALOL
  • DILTIAZEM
  • VERAPAMIL
  • DIGITALIS
  • CLONIDINE
  • BEPRIDIL
  • MORPHINE
  • PETHIDINE
  • TRAMADOL
  • INDOMETHACIN
  • ASPIRIN
  • ACETAMINOPHEN
  • HYDROCODONE
  • MEFLOQUINE
  • PROMETHAZINE
  • DIPHENHYDRAMINE
  • CLOZAPINE
  • PIMOZIDE
  • HALOPERIDOL
  • IMIPRAMINE
  • LORAZEPAM
  • DIAZEPAM
  • FLUPENTIXOL
  • DROPERIDOL
  • FLUPHENAZINE
  • PIPAMPERONE
  • DULOXETINE
  • CITALOPRAM
  • SERTRALINE
  • FLUOXETINE
  • PAROXETINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • SPARFLOXACIN
  • MOXIFLOXACIN
  • LEVODOPA
  • ROPINIROLE
  • BROMOCRIPTINE

Special Advise

  • Sulpidon OD 400 Tablet is not recommended for use in the children below 18 years of age. 
  • Sulpidon OD 400 Tablet should be used with caution in the older patient (above 65 years) and Parkinson's patient. 

Disease/Condition Glossary

Schizophrenia (psychosis): It is a mental illness in which brain information processing is affected. Patients with schizophrenia develop symptoms such as hallucinations (see or hear unreal things), delusions (false beliefs) and become withdrawn from society. They lose the ability to differentiate reality from false beliefs Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, mental trauma. Schizophrenia may also occur due to traumatic brain injuries or other diseases.

Bipolar disorder: Patients with bipolar disorders have mood swings ranging from manic episodes of heightened excitement to severe depression. It used to be known as manic depression.

Nausea/Vomiting: It is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition and dehydration. 

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