SUPRAL PLUS TABLET belongs to the class of antipsychotics used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by symptoms of hallucinations (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. SUPRAL PLUS TABLET prevents the occurrence of these symptoms. 

SUPRAL PLUS TABLET consists of two medicines, namely: Fluoxetine and Olanzapine. SUPRAL PLUS TABLET works by helping to restore the balance of certain natural substances in the brain. The key action of SUPRAL PLUS TABLET is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether SUPRAL PLUS TABLET may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

You are suggested to take $ame for as long as your doctor has prescribed it. Common side-effects of SUPRAL PLUS TABLET are drowsiness, lightheadedness, restlessness, irritability, tremor, dry mouth, constipation, increased appetite, extreme fatigue, decreased libido, swelling of the hands or feet, or weight gain. Inform your doctor if any of these side effects persist or worsen.

Do not take SUPRAL PLUS TABLET if you are allergic (hypersensitive) to any of the ingredients present in this medicine. Inform your doctor if you have a medical history of dementia, glaucoma (increased pressure in the eye), stroke, heart diseases, diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy (seizures), prostate problems, a blocked intestine (Paralytic ileus), and blood disorders. SUPRAL PLUS TABLET may increase blood glucose levels, so inform your doctor immediately if you have symptoms such as increased thirst or urination. It may also cause weight gain and increase fat levels in the body.

SUPRAL PLUS TABLET is used in the treatment of schizophrenia or psychosis and bipolar disorder (manic depression). SUPRAL PLUS TABLET works by helping to restore the balance of certain natural substances in the brain. The key action of SUPRAL PLUS TABLET is to block some of the dopamine receptors in the brain and to correct the overactivity of dopamine. On the other hand, it also affects other brain neurotransmitters, such as serotonin (5-HT), which may lead to its beneficial effects. Altogether SUPRAL PLUS TABLET may help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.

• Drowsiness
• Dizziness
• Restlessness
• Tremor
• Stomach upset
• Dry mouth
• Constipation

Do not take SUPRAL PLUS TABLET if you are allergic (hypersensitive) to any of the ingredients present in this medicine or have a medical history of eye problems such as glaucoma (increased pressure in the eye). Before taking SUPRAL PLUS TABLET, talk to your doctor if you or your family have a history of blood clots, stroke, or heart diseases and if you are above 65 years and have a history of dementia (memory loss). SUPRAL PLUS TABLET may cause weight gain and increase blood glucose and cholesterol levels. Inform your doctor if you are previously diagnosed with diabetes, liver or kidney disease, Parkinson’s disease (brain disorder), epilepsy, prostate problems, a blocked intestine (Paralytic ileus) or blood disorders.

Drug-Drug Interactions: SUPRAL PLUS TABLET may interact with other benzodiazepines or anti-anxiety drugs (lorazepam and diazepam) and opioid analgesics (tramadol and codeine).

Drug-Food Interactions: SUPRAL PLUS TABLET may interact with alcohol, increasing drowsiness.

Drug-Disease Interactions: SUPRAL PLUS TABLET should be used with caution in patients with dementia, CNS (central nervous system) depression, obesity, eye problems, acute alcohol intoxication (change in mental behaviour after alcohol consumption), brain stroke, heart diseases, hyperlipidemia (lipid alterations), hyperglycemia/diabetes, liver disease, kidney problems, epilepsy, and parkinsonism (brain disorder).

• LORAZEPAM
• TRAMADOL
• DIAZEPAM
• CODEINE

• Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine, and activities that can impact your mood. 
• Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
• You may also practice calming techniques such as meditation and deep breathing exercises.
• Sleep well. Having enough sleep will help to stabilize your mood.
• Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
• Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.

Schizophrenia (psychosis): It is a mental illness in which the processing of brain information is affected. Patients with schizophrenia develop symptoms such as hallucinations (seeing or hearing unreal things), delusions (false beliefs), and become withdrawal from society. They lose the ability to differentiate reality from false beliefs. Patients with bipolar disorders have mood swings ranging from manic episodes of heightened excitement to severe depression. Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, or mental trauma. Schizophrenia may also occur due to brain injuries or diseases.

Bipolar disorder: It is a mental health condition that affects your moods, which can swing from one extreme to another. It is also known as manic depression.