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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

PROGESTERONE-400MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Susten SR 400 Tablet

Susten SR 400 Tablet belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, Susten SR 400 Tablet also treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Susten SR 400 Tablet contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Susten SR 400 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Susten SR 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Susten SR 400 Tablet or any other medicines, please tell your doctor. Avoid taking Susten SR 400 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Susten SR 400 Tablet if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Susten SR 400 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Susten SR 400 Tablet . Drive only if you are alert as Susten SR 400 Tablet may cause drowsiness or dizziness.

Uses of Susten SR 400 Tablet

Female infertility, Female hormonal imbalance

Directions for Use

Take Susten SR 400 Tablet as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take Susten SR 400 Tablet at bedtime as it may cause dizziness or drowsiness.

Medicinal Benefits

Susten SR 400 Tablet contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Susten SR 400 Tablet is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Susten SR 400 Tablet replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour.

Storage

Store in a cool and dry place away from sunlight
Side effects of Susten SR 400 Tablet
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Drug Warnings

If you are allergic to soya, Susten SR 400 Tablet or any other medicines, please tell your doctor. Avoid taking Susten SR 400 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Susten SR 400 Tablet if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Susten SR 400 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Susten SR 400 Tablet . Drive only if you are alert as Susten SR 400 Tablet may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Susten SR 400 Tablet . If you are about to undergo any surgery, please inform your doctor that you are taking Susten SR 400 Tablet .

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
ProgesteroneEdoxaban
Severe

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
How does the drug interact with Susten SR 400 Tablet:
Co-administration of Susten SR 400 Tablet with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Susten SR 400 Tablet and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneEdoxaban
Severe
How does the drug interact with Susten SR 400 Tablet:
When Susten SR 400 Tablet is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Susten SR 400 Tablet and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneMorphine
Severe
How does the drug interact with Susten SR 400 Tablet:
Co-administration of Susten SR 400 Tablet with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Susten SR 400 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Susten SR 400 Tablet Substitute

Substitutes safety advice
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  • Endogest 400 SR Tablet 10's

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Susten SR 400 Tablet contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Susten SR 400 Tablet may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Susten SR 400 Tablet and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Susten SR 400 Tablet reduces this risk.

You are recommended to inform your doctor that you are taking Susten SR 400 Tablet as you may need to stop taking Susten SR 400 Tablet 4 to 6 weeks before surgery to decrease the risk of blood clot.

Susten SR 400 Tablet may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

Susten SR 400 Tablet is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Susten SR 400 Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • RITONAVIR
  • NEVIRAPINE
  • NELFINAVIR
  • EFAVIRENZ
  • DIAZEPAM
  • SPIRONOLACTONE
  • CICLOSPORIN
  • PHENINDIONE
  • TIZANIDINE
  • TERBINAFINE
  • KETOCONAZOLE
  • GRISEOFULVIN

Special Advise

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Disease/Condition Glossary

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

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