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Reviewed By Sureshvarma D , MPharma
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Composition

SUNITINIB-50MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Sutinat 50 Capsule 28's

Sutinat 50 Capsule 28's belongs to the class of medications called ‘antineoplastic agents’ used in treating gastrointestinal stromal tumors (cancer of the stomach, bowel, or esophagus) in which patients don’t respond to imatinib (another anticancer agent). It is also used to treat renal carcinoma (kidney cancer) that has spread to other parts of the body and advanced pancreatic neuroendocrine tumors (cancer that has affected hormone-producing cells in the pancreas).

Sutinat 50 Capsule 28's contains sunitinib. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell death eventually.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Sutinat 50 Capsule 28's are difficulty breathing, increase in blood pressure, extreme tiredness, swelling caused by fluid under the skin and around the eye, pain or irritation in the mouth, mouth sores, dry mouth, taste disturbances, upset stomach, nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, decreased activity of thyroid gland (hypothyroidism), dizziness, headache, nose bleeding, back pain, joint pain, pain in arms and legs, yellowish discoloration of the skin, rash on the palms of the hands and soles of the feet, dryness of the skin, cough, fever, and difficulty to sleep. Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take Sutinat 50 Capsule 28's if you are allergic to any contents of it. Sutinat 50 Capsule 28's should be used with caution in patients with high blood pressure, heart problems, diabetes, liver or kidney problems, skin disorders, pancreas or gallbladder problems, history of blood clots, aneurysm (weakening of blood vessel wall), problems with the thyroid gland, pancreas, and gallbladder, liver or kidney problems, and thrombotic microangiopathy (damage to the smallest blood vessels). It is not recommended for use in children and adolescents under 18 years of age. It should be used with caution in pregnant and breastfeeding women. Do not consume alcohol as it may increase the risk of side-effects. Sutinat 50 Capsule 28's may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Sutinat 50 Capsule 28's

Gastrointestinal stromal cancer, kidney cancer, and pancreatic neuroendocrine tumors.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Sutinat 50 Capsule 28's is a targeted therapy used to treat advanced kidney cancer. It is also used in patients with kidney cancer to prevent recurrence after having kidney surgery. It is used to treat gastrointestinal stromal cancer that cannot be treated with imatinib, another anti-cancer medicine. It is used to manage pancreatic neuroendocrine tumors (cancer of hormone-producing cells of the pancreas) that cannot be treated with surgery. Sutinat 50 Capsule 28's can help to manage the above conditions if taken regularly as prescribed by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sutinat 50 Capsule 28's

  • Tiredness
  • Pain or irritation in the mouth
  • Mouth sores
  • Dry mouth
  • Taste disturbances
  • Upset stomach
  • Nausea
  • Vomiting
  • Diarrhea or constipation
  • Abdominal pain
  • Loss of appetite
  • Dizziness
  • Headache
  • Back pain
  • Joint pain
  • Yellowish discoloration of the skin
  • Rash on the palms of the hands and soles of the feet
  • Dryness of the skin
  • Cough
  • Fever
  • Difficulty to sleep

Drug Warnings

Sutinat 50 Capsule 28's may cause an increase in blood pressure. So, your doctor may monitor your blood pressure regularly and prescribe blood-pressure-lowering medicines if necessary. Sutinat 50 Capsule 28's may increase the risk of bleeding, and the risk is high if you are taking any blood thinners such as warfarin and acenocoumarol. Sutinat 50 Capsule 28's may cause heart problems, so notify your doctor if you experience extreme tiredness, shortness of breath, and swelling of the feet and ankles. Sutinat 50 Capsule 28's may cause heart rhythm abnormalities, so inform your doctor if you experience dizziness or abnormal heartbeats. Sutinat 50 Capsule 28's should be used with caution in patients with a recent history of blood clots, heart attack, or stroke as this medicine may cause chest pain, shortness of breath, difficulty speaking, weakness of one side of the body, or dizziness. Sutinat 50 Capsule 28's should be used with caution in patients with aneurysm (weakening of blood vessel wall), thrombotic microangiopathy (damage to the small blood vessels), and liver or kidney problems. Sutinat 50 Capsule 28's may cause inflammation of the pancreas or gallbladder and lead to symptoms such as abdominal pain (upper abdominal region), fever, and vomiting, in patients with a history of pancreatic or gallbladder disorders. Sutinat 50 Capsule 28's may cause thyroid gland problems, so inform your doctor if you experience frequent fatigue and extreme cold than others. Sutinat 50 Capsule 28's may cause skin ulceration (pyoderma gangrenosum) or infection (necrotizing fasciitis). So, inform your doctor if you notice symptoms of infection around a skin injury such as fever, pain, swelling, redness, and drainage of pus or blood from the wound. However, these effects are usually reversible after the discontinuation of therapy. If you develop severe skin rashes, especially with blistering or peeling of the skin, notify your doctor immediately as it can be a sign of a serious skin condition. Sutinat 50 Capsule 28's may cause headaches, high blood pressure, and vision problems in patients with a history of fits or seizures. While using Sutinat 50 Capsule 28's, blood sugar levels should be monitored regularly in patients with diabetes. In addition, notify your doctor immediately if you notice signs of low blood sugar such as fatigue, hunger, sweating, pounding heartbeat, and loss of consciousness.

Drug-Drug Interactions

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SunitinibDexamethasone
Severe
SunitinibImipramine
Severe

Drug-Drug Interactions

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SunitinibDexamethasone
Severe
How does the drug interact with Sutinat 50 Capsule:
Taking Dexamethasone may lower the blood levels of Sutinat 50 Capsule in some patients, making the medication less effective.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Sutinat 50 Capsule if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
SunitinibImipramine
Severe
How does the drug interact with Sutinat 50 Capsule:
Taking Imipramine with Sutinat 50 Capsule can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Imipramine with Sutinat 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibMoxifloxacin
Severe
How does the drug interact with Sutinat 50 Capsule:
Using moxifloxacin together with Sutinat 50 Capsule can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Sutinat 50 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heart rhythm, severe diarrhea, or dizziness, it is important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
SunitinibSotalol
Severe
How does the drug interact with Sutinat 50 Capsule:
Using sotalol together with Sutinat 50 Capsule can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Sutinat 50 Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibCeritinib
Severe
How does the drug interact with Sutinat 50 Capsule:
Taking Sutinat 50 Capsule with ceritinib can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Ceritinib with Sutinat 50 Capsule together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SunitinibNilotinib
Severe
How does the drug interact with Sutinat 50 Capsule:
Combining Sutinat 50 Capsule and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sutinat 50 Capsule and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SunitinibCarbamazepine
Severe
How does the drug interact with Sutinat 50 Capsule:
Taking Sutinat 50 Capsule with carbamazepine together may reduce the blood levels of Sutinat 50 Capsule, which may make the medication less effective

How to manage the interaction:
Although taking carbamazepine and Sutinat 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SunitinibChloroquine
Severe
How does the drug interact with Sutinat 50 Capsule:
Using chloroquine together with Sutinat 50 Capsule can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Sutinat 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SunitinibGlimepiride
Severe
How does the drug interact with Sutinat 50 Capsule:
Taking glimepiride with Sutinat 50 Capsule may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Sutinat 50 Capsule if prescribed by the doctor. Consult the prescriber if you experience symptoms if low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
SunitinibDisopyramide
Severe
How does the drug interact with Sutinat 50 Capsule:
The combined use of Sutinat 50 Capsule and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Sutinat 50 Capsule and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet that includes fresh fruits and vegetables.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugars.
  • Maintain a healthy weight.
  • Avoid smoking and alcohol consumption.
  • Manage stress and use relaxation techniques such as meditation and yoga.
  • Get optimal sleep, rest well.
  • Limit exposure to environmental toxins such as smoke, asbestos, or other chemicals.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Sutinat 50 Capsule 28's Substitute

Substitutes safety advice
  • Nitnib 50 Capsule 7's

    by Others

    230.79per tablet
  • Sutykine 50 Cap 7'S

    by Others

    237.86per tablet
  • SUTENT 50MG CAPSULE 7'S

    by Others

    7146.12per tablet
  • Adsunib 50 Capsule 28's

    by Others

    216.71per tablet
  • Sutib 50 Capsule 7's

    by Others

    225.00per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • DEXAMETHASONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • HYPERICUM PERFORATUM
  • WARFARIN
  • ACENOCOUMAROL

Special Advise

  • Let your doctor know before undergoing any surgery that you are taking Sutinat 50 Capsule 28's as this medicine may delay wound healing.
  • Your doctor may advise you to undergo a dental check-up before starting treatment with Sutinat 50 Capsule 28's. In addition, inform your doctor that you are taking Sutinat 50 Capsule 28's if you are undergoing any dental treatment or surgery, especially if you are taking bisphosphonates (medications used to prevent bone complications.
  • Use reliable contraception while using Sutinat 50 Capsule 28's to prevent pregnancy.

Disease/Condition Glossary

Gastrointestinal stromal tumor: It is cancer that affects the stomach and small intestine. It shows no or mild symptoms during the initial stages. It may cause blood in the stool or vomit as the disease progresses. In general, surgery is preferred for the treatment. However, imatinib or sunitinib (targeted therapy) can be given to shrink the tumor or if the tumor cannot be removed by surgery. 

Kidney cancer: It is also called renal cell carcinoma. It is the most common type of cancer seen in adults. Symptoms include red, orange, or pink-colored urine due to the presence of blood in the urine. In advanced kidney cancer (that has spread to other parts of the body), treatment is given to improve the survival rate.

Pancreatic neuroendocrine tumors: It is a type of endocrinal tumor that arises in the pancreas. Symptoms include yellowish skin or whites of the eyes, diarrhea, indigestion, stomach pain, and weight loss. Surgery, hormonal therapy, chemotherapy, and targeted therapy can be given to treat this type of tumor. 

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