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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma

About Synac R Tablet

Synac R Tablet belongs to a class of drugs called analgesics (pain relievers) used to reduce pain and swelling in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The symptoms of arthritis include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

Synac R Tablet is a combination of three drugs, namely: Aceclofenac (nonsteroidal anti-inflammatory drug), Paracetamol (analgesic and antipyretic), and Rabeprazole (proton pump inhibitor).  Aceclofenac and Paracetamol work by inhibiting the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis. Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe.

Take Synac R Tablet as prescribed by your doctor. You are advised to take Synac R Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea. Most of these side effects of Synac R Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Synac R Tablet or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Synac R Tablet as it may cause adverse effects in the baby if taken during the last 3 months of pregnancy. Synac R Tablet may be excreted in breast milk. Therefore, avoid breastfeeding and consult a doctor. Synac R Tablet is not recommended for children below 18 years of age as the safety and effectiveness were not established. Avoid consumption of alcohol with Synac R Tablet as it may increase the risk of stomach bleeding. Drive only if you are alert as Synac R Tablet may cause dizziness, tiredness, drowsiness, or vision problems.

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Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Synac R Tablet

Osteoarthritis, Rheumatoid arthritis and Ankylosing spondylitis

Medicinal Benefits

Synac R Tablet contains Aceclofenac, Paracetamol and Rabeprazole.  Aceclofenac and Paracetamol inhibit the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis (pain and stiffness in the backbone). Rabeprazole blocks the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe.

Side Effects of Synac R Tablet

  • Indigestion
  • Stomach pain
  • Constipation
  • Dizziness
  • Nausea
  • Diarrhoea

Directions for Use

Take Synac R Tablet with food to avoid stomach upset or as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Synac R Tablet or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Synac R Tablet as it may cause adverse effects in the baby if taken during the last 3 months of pregnancy. Synac R Tablet may be excreted in breast milk. Therefore, avoid breastfeeding and consult a doctor. Synac R Tablet is not recommended for children below 18 years of age as the safety and effectiveness were not established. Avoid consumption of alcohol with Synac R Tablet as it may increase the risk of stomach bleeding. Drive only if you are alert as Synac R Tablet may cause dizziness, tiredness, drowsiness or vision problems.

Therapeutic Class

ANALGESICS

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
RabeprazoleErlotinib
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with Synac R Tablet:
Co-administration of Synac R Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Synac R Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleErlotinib
Critical
How does the drug interact with Synac R Tablet:
When used in combination with erlotinib, Synac R Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Synac R Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleClopidogrel
Severe
How does the drug interact with Synac R Tablet:
Taking Clopidogrel with Synac R Tablet can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Synac R Tablet together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
RabeprazoleMethotrexate
Severe
How does the drug interact with Synac R Tablet:
Co-administration of Methotrexate with Synac R Tablet can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Synac R Tablet and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Synac R Tablet:
Taking Synac R Tablet together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Synac R Tablet and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleAtazanavir
Severe
How does the drug interact with Synac R Tablet:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Synac R Tablet, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Synac R Tablet and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleDasatinib
Severe
How does the drug interact with Synac R Tablet:
Taking Synac R Tablet together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Synac R Tablet and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Synac R Tablet:
Taking Synac R Tablet together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Synac R Tablet and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazolePhenytoin
Severe
How does the drug interact with Synac R Tablet:
When Phenytoin and Synac R Tablet are taken in combination, Phenytoin will reduce the concentration or impact of Synac R Tablet.

How to manage the interaction:
Although taking Phenytoin and Synac R Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with Synac R Tablet:
When Synac R Tablet and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Synac R Tablet.

How to manage the interaction:
Although taking Synac R Tablet and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • ETORICOXIB
  • ASPIRIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • PROPRANOLOL
  • ENALAPRIL
  • LISINOPRIL
  • LOSARTAN
  • CANDESARTAN
  • METHYLDOPA
  • CLONIDINE
  • FUROSEMIDE
  • AMILORIDE
  • HEPARIN
  • WARFARIN
  • CLOPIDOGREL
  • GLIBENCLAMIDE
  • GLICLAZIDE
  • TOLBUTAMIDE
  • MOXIFLOXACIN
  • CIPROFLOXACIN
  • OFLOXACIN
  • LEVOFLOXACIN
  • CHLORAMPHENICOL
  • ZIDOVUDINE
  • FLUVOXAMINE
  • PAROXETINE
  • CITALOPRAM
  • ESCITALOPRAM
  • SERTRALINE
  • FLUOXETINE
  • LITHIUM
  • METHOTREXATE
  • MIFEPRISTONE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • HYDROCORTISONE
  • PREDNISOLONE
  • CICLOSPORIN
  • TACROLIMUS

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

If you are elderly, a smoker, had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.

Author Details

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Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms include pain, swelling, stiffness, deformities, and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture, pain, and back and joints.

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