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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ITRACONAZOLE-200MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Syntran 200 Capsule

Syntran 200 Capsule belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Syntran 200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Syntran 200 Capsule as prescribed. Your doctor will advise you on how often you take Syntran 200 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Syntran 200 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Syntran 200 Capsule or any other medicines, please tell your doctor. Syntran 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Syntran 200 Capsule . Do not take Syntran 200 Capsule if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Syntran 200 Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Syntran 200 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Syntran 200 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Syntran 200 Capsule

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Syntran 200 Capsule with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Syntran 200 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Syntran 200 Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Syntran 200 Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

If you are known to be allergic to Syntran 200 Capsule or any other medicines, please tell your doctor. Syntran 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Syntran 200 Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Syntran 200 Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Syntran 200 Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Syntran 200 Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Syntran 200 Capsule .

Drug-Drug Interactions

verifiedApollotooltip
ItraconazoleColchicine
Critical
ItraconazoleAvanafil
Critical

Drug-Drug Interactions

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Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Syntran 200 Capsule Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Syntran 200 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Syntran 200 Capsule with other medicines.

No, Syntran 200 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Syntran 200 Capsule and after 2 months of stopping treatment with Syntran 200 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Syntran 200 Capsule .

Syntran 200 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Syntran 200 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Syntran 200 Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Syntran 200 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Syntran 200 Capsule because antacids decrease the absorption and blood levels of Syntran 200 Capsule . However, please consult a doctor before taking other medicines with Syntran 200 Capsule .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Syntran 200 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Syntran 200 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Syntran 200 Capsule , please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Syntran 200 Capsule to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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