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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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About Systaflam Gel

Systaflam Gel is a combination medicine used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation, redness and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps in improving blood circulation and provides relief from pain. Turpentine Oil is a lubricant.

Systaflam Gel is for external use only. Avoid getting the Systaflam Gel in contact with your eyes, nose or mouth. Do not apply it to wounded or damaged skin. In case of accidental contact, immediately rinse it with cold water. Like all medicines, Systaflam Gel can cause side effects, although not everybody gets them. You might experience side effects such as a burning sensation, irritation, itching and redness at the application site. Most of these side effects of Systaflam Gel do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use this medicine without consulting your doctor. Even though drugs used topically (directly applied) on the skin are not normally affected by any other medication, you should inform your doctor if you are taking any other medicine. Also, inform your doctor if you have had an allergic reaction to diclofenac or any other drugs in the past, any cut or infected skin and ever had signs of any lung, liver, kidney-related diseases/disorders, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea). Please tell your doctor if you are pregnant or breastfeeding to avoid unnecessary risks.

Uses of Systaflam Gel

Pain and Inflammation associated with musculoskeletal and joint disorders.

Directions for Use

Gel/Cream/Ointment: Systaflam Gel is only for external use. Take a small amount of Systaflam Gel on the fingertip and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor. Avoid contact of the Systaflam Gel with the nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly. Wash your hands before and after using Systaflam Gel if your hands are not the affected area to prevent the spread of infection.Spray: It is only for external use. Check the label for directions before using the spray. Shake well before each use. Spray the contents from a 5cm distance on the affected area.

Medicinal Benefits

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil, and Methyl salicylate. Here, diclofenac works by blocking the release of certain chemical messengers in the brain responsible for causing pain and signs of inflammation such as redness and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. On the other hand, methyl salicylate and menthol work by causing the skin to feel cool and warm. This action helps improve blood circulation and thus provides relief from pain. Turpentine Oil is a lubricant.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Systaflam Gel as it may lead to an increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure and liver or kidney disease should not take Systaflam Gel. Besides this, it should be avoided during the last trimester of pregnancy unless the doctor has prescribed you. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Systaflam Gel.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In the chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids with a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Systaflam Gel Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain responsible for causing pain and symptoms of inflammation, redness and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps in improving blood circulation and provides relief from pain. Turpentine Oil is a lubricant.

Avoid concomitant use of Systaflam Gel with other topical products such as cosmetics, sunscreens, lotions, moisturizers, insect repellent creams, and other gels.

Please do not take any NSAID/painkiller medicines along with Systaflam Gel as it could increase the risk of ulceration, perforation, and bleeding in the stomach and intestine. Inform your doctor before using Systaflam Gel if you are taking any NSAIDs orally.

No, use of Systaflam Gel is contraindicated on the broken or cut wound skin. It should be only applied topically on the uppermost skin surfaces (epidermis). It should not be applied in the nostrils, vagina or anus.

No, it is not advised to use Systaflam Gel in patients with severe heart failure.

Avoid or limit exposure to natural or artificial sunlight as Systaflam Gel may cause ultraviolet light-induced skin tumours.

Drug-Drug Interactions Checker List

  • METHADONE
  • WARFARIN
  • ASPIRIN
  • FUROSEMIDE
  • DIGOXIN

Special Advise

  • Caution should be exercised, and it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.
  • Systaflam Gel should not be applied to cut or open skin wounds for pain relief.

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic and can be localized or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Musculoskeletal pain symptoms include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, cracking, or popping sounds at the joints.

Osteoarthritis: Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

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