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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Systaflam MR Capsule

Systaflam MR Capsule is a combination medication primarily used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, torticollis (neck muscle contractions), and upper and lower back pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Systaflam MR Capsule is a combination of two drugs: Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Systaflam MR Capsule include nausea, vomiting, loss of appetite, stomach pain, diarrhoea, and heartburn. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Systaflam MR Capsule , inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. Systaflam MR Capsule is not recommended for pregnant and breastfeeding women. Systaflam MR Capsule should not be given to children and adolescents below 18 years of age as safety has not been established. Avoid consuming alcohol while undergoing treatment with Systaflam MR Capsule . 

Uses of Systaflam MR Capsule

Pain due to muscle spasms.

Directions for Use

Swallow it as a whole with a glass of water. Do not chew, crush or break it.

Medicinal Benefits

Systaflam MR Capsule treats pain due to muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAIDs) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. Please consult your doctor before starting Systaflam MR Capsule if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Systaflam MR Capsule unless prescribed. Stop taking Systaflam MR Capsule and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Systaflam MR Capsule is not recommended for pregnant and breastfeeding women. Systaflam MR Capsule may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol while being treated with Systaflam MR Capsule . This medicine is not recommended in children and adolescents below 18 years of age as safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Systaflam MR Capsule:
Co-administration of Systaflam MR Capsule with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Systaflam MR Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Systaflam MR Capsule:
Co-administration use of Systaflam MR Capsule with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Systaflam MR Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Systaflam MR Capsule:
Co-administration of Systaflam MR Capsule and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Systaflam MR Capsule and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Systaflam MR Capsule:
Taking Systaflam MR Capsule with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Systaflam MR Capsule, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Systaflam MR Capsule:
Coadministration of Systaflam MR Capsule and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Systaflam MR Capsule and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacMipomersen
Severe
How does the drug interact with Systaflam MR Capsule:
Co-administration of Systaflam MR Capsule with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Systaflam MR Capsule and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Systaflam MR Capsule:
Coadministration of Systaflam MR Capsule with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Systaflam MR Capsule and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Systaflam MR Capsule:
Coadministration of Systaflam MR Capsule with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Systaflam MR Capsule and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Systaflam MR Capsule:
Taking amiloride with Systaflam MR Capsule can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Systaflam MR Capsule and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Systaflam MR Capsule:
Co-administration of Systaflam MR Capsule with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Systaflam MR Capsule and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Systaflam MR Capsule contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that relieves muscle stiffness due to muscle spasms and improves muscle movements.

Systaflam MR Capsule is usually prescribed for a short period and can be discontinued if there is no pain. To treat your condition effectually, continue taking Systaflam MR Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Systaflam MR Capsule .

Diarrhoea can be a side-effect of Systaflam MR Capsule . Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

It is not advised to use other NSAIDs or pain killers while using Systaflam MR Capsule . Please seek medical advice for further information.

You are not recommended to take Systaflam MR Capsule with warfarin as simultaneous use of these two medicines may increase the bleeding risk. However, if you are supposed to use these medicines together, please contact your doctor so that the dose may be adjusted or you may be prescribed alternate medicine.

Drug-Drug Interactions Checker List

  • WARFARIN
  • LITHIUM
  • METHOTREXATE
  • CICLOSPORIN
  • TACROLIMUS
  • TRIMETHOPRIM
  • MIFEPRESTONE
  • ASPIRIN
  • IBUPROFEN
  • DIGOXIN
  • VORICONAZOLE
  • PHENYTOIN
  • COLESTIPOL
  • CHOLESTYRAMINE

Special Advise

  • Let your doctor know that you are taking Systaflam MR Capsule if you are undergoing any medical tests.
  • Your doctor may recommend liver function tests to monitor your liver functioning.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. At the same time, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.

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