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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Marsha Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Systel Tablet

Systel Tablet belongs to a class of antipsychotic medications called phenothiazines used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness. 

Systel Tablet contains Prochlorperazine which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting center (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, Systel Tablet also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. 

Take Systel Tablet as prescribed by your doctor. You are advised to take Systel Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling.  Most of these side effects of Systel Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Systel Tablet if you are known to be allergic to Systel Tablet . Systel Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Systel Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Systel Tablet is not recommended for children below 1 year of age. Avoid exposure to direct sunlight while taking Systel Tablet as it may cause the skin to be more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumor on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Systel Tablet .

Uses of Systel Tablet

Nausea and vomiting in migraine, Schizophrenia, Anxiety disorder

Directions for Use

Take Systel Tablet with or without food as advised by your doctor.Tablet: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Avoid contact of tablet with your skin for a very long time as you it may cause swelling, skin redness, and itching (contact skin sensitization).Tablet MD: Place the mouth dissolving tablet in the mouth and allow it to dissolve. Do not swallow. Avoid handling the tablets with wet hands.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Systel Tablet contains Prochlorperazine that inhibits dopamine secretion that induces the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Systel Tablet prevents nausea and vomiting. Also, Systel Tablet control psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

Storage

Store in a cool and dry place away from sunlight
Side effects of Systel Tablet
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Drug Warnings

Do not take Systel Tablet if you are known to be allergic to Systel Tablet . Systel Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Systel Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Systel Tablet is not recommended for children below 1 year of age. Avoid consumption of alcohol with Systel Tablet as it may increase adverse effects. You are recommended to avoid contact of Systel Tablet with the skin for a long time as it may cause swelling, redness or itching of the skin. Avoid exposure to direct sunlight while taking Systel Tablet as it may cause skin to more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Systel Tablet .

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Systel Tablet:
Coadministration of metoclopramide and Systel Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Systel Tablet together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Systel Tablet:
Coadministration of mesoridazine and Systel Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Systel Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
ProchlorperazineAnagrelide
Severe
How does the drug interact with Systel Tablet:
Taking Systel Tablet and Anagrelide together can increase the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Systel Tablet and anagrelide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineVemurafenib
Severe
How does the drug interact with Systel Tablet:
Taking Systel Tablet and Vemurafenib together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Systel Tablet and Vemurafenib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without first talking to your doctor.
ProchlorperazineKetamine
Severe
How does the drug interact with Systel Tablet:
Coadministration of Systel Tablet with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Systel Tablet with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
ProchlorperazineSaquinavir
Severe
How does the drug interact with Systel Tablet:
Taking Systel Tablet and saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Systel Tablet with Saquinavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineMoxifloxacin
Severe
How does the drug interact with Systel Tablet:
Using moxifloxacin together with Systel Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Systel Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience symptoms like an irregular heart rhythm, a heart condition, or sudden dizziness, it is important to call your doctor right away. Do not discontinue any medications without consulting your doctor.
ProchlorperazineHaloperidol
Severe
How does the drug interact with Systel Tablet:
Coadministration of Systel Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Coadministration of Systel Tablet and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
ProchlorperazineBepridil
Severe
How does the drug interact with Systel Tablet:
Taking Systel Tablet and Bepridil together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Systel Tablet and Bepridil, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineDisopyramide
Severe
How does the drug interact with Systel Tablet:
Taking Systel Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Disopyramide with Systel Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a fast or irregular heartbeat, dizziness, fainting, shortness of breath, or severe diarrhoea or vomiting, it's important to call your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.
  • If you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Include more cool beverages in your food like flavoured gelatin, carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.
  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Systel Tablet Substitute

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Systel Tablet contains Prochlorperazine, an antipsychotic drug that works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Systel Tablet prevents nausea and vomiting. Also, Systel Tablet decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia.

Yes, Systel Tablet may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).

Systel Tablet may cause photosensitivity (extreme sensitivity to sunlight). Therefore, it is recommended to avoid exposure to direct sunlight while taking Systel Tablet .

You are not recommended to take Systel Tablet with alprazolam as co-administration of these medicines may increase adverse effects such as confusion, drowsiness, dizziness and difficulty in concentrating. However, please contact your doctor before using Systel Tablet with other medicines.

Systel Tablet should be used with caution in diabetes patients as it may cause an increase in blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Systel Tablet if you are diabetic.

Systel Tablet may cause skin redness, itching and swelling if it comes in contact with the skin for a long time. Therefore, avoid contact of Systel Tablet with the skin for a long time as it may cause contact skin sensitization.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • FENTANYL
  • HYDROCODONE
  • POLYETHYLENE GLYCOL
  • PREGABALIN
  • DIPHENHYDRAMINE
  • LORAZEPAM
  • ALPRAZOLAM
  • DULOXETINE
  • ONDANSETRON

Special Advise

Avoid exposure to direct sunlight while taking Systel Tablet as it may cause the skin to be more sensitive to sunlight.

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

 

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly.

 

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. The anxiety symptoms include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.

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