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Composition :

TACROLIMUS-0.03%W/V

Manufacturer/Marketer :

Inex Medicaments Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tacronex-PG Solution

Tacronex-PG Solution belongs to a class of drugs called immunosuppressants used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Tacronex-PG Solution contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thus, prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Take Tacronex-PG Solution as prescribed. You are advised to use Tacronex-PG Solution for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of Tacronex-PG Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex-PG Solution. Avoid alcohol consumption with Tacronex-PG Solution. Drive only if you are alert, as Tacronex-PG Solution may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking Tacronex-PG Solution. Tacronex-PG Solution may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of Tacronex-PG Solution

Prevent transplanted organ rejection

Directions for Use

Capsule: Take the capsule as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Granules: The granules should be mixed with water to make an oral suspension. Drink the prepared suspension immediately. Do not save the suspension for later use.

Medicinal Benefits

Tacronex-PG Solution contains Tacrolimus, an immunosuppressant used to prevent organ rejection after a transplant. Tacronex-PG Solution suppresses the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tacronex-Pg 15Ml Liq
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex-PG Solution. Avoid alcohol consumption with Tacronex-PG Solution. Drive only if you are alert, as Tacronex-PG Solution may cause vision problems or nervous disturbances in some people. If you are about to get vaccinated, inform your doctor before taking Tacronex-PG Solution. Tacronex-PG Solution may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking Tacronex-PG Solution, you are advised to wear protective clothing and sunscreen while going out. You are recommended to use glass or metal materials to prepare the oral suspension. Avoid using plastic (PVC) materials to prepare the suspension as the granules will stick to a plastic container, and your child may not receive their full dose. Do not inhale or let the granules or prepared oral suspension come in contact with your skin or eyes. In case of accidental contact with skin, wash the area well with soap and water, and if it comes in contact with the eyes, rinse with plain water.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tacronex-Pg 15Ml Liq:
Combining Tacronex-Pg 15Ml Liq with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with Mifepristone may significantly increase the blood levels of Tacronex-Pg 15Ml Liq, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking cidofovir with Tacronex-Pg 15Ml Liq can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacronex-Pg 15Ml Liq with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq together with Escitalopram can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Tacronex-Pg 15Ml Liq and escitalopram together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with etodolac may increase risk of kidney problems.

How to manage the interaction:
Although taking Tacronex-Pg 15Ml Liq and etodolac together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Co-administration of Tacronex-Pg 15Ml Liq with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tacronex-Pg 15Ml Liq and valacyclovir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tacronex-Pg 15Ml Liq:
Taking Tacronex-Pg 15Ml Liq with gentamicin may cause kidney problems.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Tacronex-Pg 15Ml Liq if prescribed by the doctor. However, consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TACROLIMUS-0.03%W/VGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-0.03%W/VGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacronex-Pg 15Ml Liq treatment may lead to increased Tacronex-Pg 15Ml Liq levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacronex-Pg 15Ml Liq.

Diet & Lifestyle Advise

Kidney transplant:

  • Include fruits and vegetables in your daily routine.
  • Follow a vitamin-C-rich diet.
  • Reduce salt intake.
  • Eat a handful of walnuts and almonds every day.
  • Reduce intake of unhealthy cholesterol and fats.
  • Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

  • Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
  • Maintain a low-fat and low-salt diet.
  • Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
  • Stay hydrated by drinking sufficient water and other fluids.
  • Avoid alcohol consumption.
  • Avoid grapefruit and grapefruit juice. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tacronex-PG Solution contains Tacrolimus, an immunosuppressant that works by the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Tacronex-PG Solution may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as sore throat or fever.

Tacronex-PG Solution may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Tacronex-PG Solution because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Tacronex-PG Solution with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Tacronex-PG Solution with other medications.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • SIROLIMUS
  • NELFINAVIR
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TRIAMTERENE
  • AMILORIDE

Special Advise

Regular blood tests and certain other tests are recommended while taking Tacronex-PG Solution to check blood sugar levels, kidney functioning and potassium levels in the blood.

Disease/Condition Glossary

Organ rejection: It occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it. Organ rejection may be hyperacute (occurs in minutes to hours), acute (occurs within the first few months), or chronic (occurs after a year or anytime beyond). The symptoms of organ rejection may vary based on the type of organ transplant you have had. However, if you experience pain, fever, or other signs of illness, contact your doctor immediately.

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