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Composition :

TACROLIMUS-0.1%W/V

Manufacturer/Marketer :

Inex Medicaments Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Tacronex Slution

Tacronex Slution belongs to a class of drugs called 'immunosuppressants' used to treat moderate to severe atopic dermatitis (eczema). Atopic dermatitis, also known as eczema, is a common skin condition associated with inflamed and itchy skin patches. The symptoms include itchy, dry, flaky, swollen, rough and irritated skin.

Tacronex Slution contains 'Tacrolimus' that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling). 

Use Tacronex Slution as prescribed. You are advised to use Tacronex Slution for as long as your doctor has recommended it for you based on your medical condition. Some people may experience itching, burning sensation, redness, pain or skin tingling. Most of these side effects of Tacronex Slution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex Slution. Avoid alcohol consumption with Tacronex Slution as it may cause flushing (sudden reddening of face or skin that makes you feel warm and hot). Do not cover or wrap the treated area with a bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacronex Slution catches fire and burns easily.

Uses of Tacronex Slution

Atopic dermatitis (eczema)

Directions for Use

Wash your hands before and after applying Tacronex Slution. Apply it as a thin layer on the clean and dry affected skin area as prescribed by your doctor. Tacronex Slution is only for external use. Avoid contact with eyes, nose or mouth as it may irritate. If Tacronex Slution accidentally comes in contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Tacronex Slution contains Tacrolimus, an immunosuppressant used to treat moderate to severe atopic dermatitis (eczema) in adults who are not adequately responsive or are intolerant to topical corticosteroids and in children (above 2 years) who failed to respond adequately to topical corticosteroids.  Tacronex Slution suppresses the overreaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling). 

Storage

Store in a cool and dry place away from sunlight
Side effects of Tacronex Slution 15 ml
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex Slution. Avoid alcohol consumption with Tacronex Slution as it may cause flushing (sudden reddening of face or skin that makes you feel warm and hot). Do not cover or wrap the treated area with a bandage or dressing. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacronex Slution catches fire and burns easily. Please avoid contact with eyes, nose or mouth as it may irritate. Do not shower, bathe or swim immediately after applying Tacronex Slution as it may wash off Tacronex Slution. If Tacronex Slution accidentally comes in contact with these areas, rinse with water thoroughly. Do not swallow Tacronex Slution. In case of accidental swallowing, consult a doctor immediately.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tacronex Slution 15 ml:
Combining Tacronex Slution 15 ml with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Mifepristone may significantly increase the blood levels of Tacronex Slution 15 ml, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking cidofovir with Tacronex Slution 15 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml together with Escitalopram can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Tacronex Slution 15 ml and escitalopram together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with etodolac may increase risk of kidney problems.

How to manage the interaction:
Although taking Tacronex Slution 15 ml and etodolac together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Co-administration of Tacronex Slution 15 ml with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tacronex Slution 15 ml and valacyclovir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with gentamicin may cause kidney problems.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Tacronex Slution 15 ml if prescribed by the doctor. However, consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacronex Slution 15 ml treatment may lead to increased Tacronex Slution 15 ml levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacronex Slution 15 ml.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish.
  • Avoid contact of your skin with harsh soaps, detergents, cleaning supplies, dust or sand, wool, synthetic fibres and cigarette smoke.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tacronex Slution contains Tacrolimus, an immunosuppressant that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling).

Tacronex Slution may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.

You are recommended to avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

You are not recommended to take a shower, swim or bath immediately after applying Tacronex Slution as water may wash off this medicine.

Tacronex Slution is flammable and can catch fire; hence, avoid smoking or going near naked flames after applying the ointment of tacrolimus.

You are recommended to use Tacronex Slution for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after using Tacronex Slution for two weeks, please consult a doctor.

Drug-Drug Interactions Checker List

  • CORTISONE

Special Advise

  • Please consult a dermatologist if the skin condition does not improve even after two weeks of treatment with Tacronex Slution.

Disease/Condition Glossary

Atopic dermatitis: It is also known as eczema, a common skin condition associated with inflamed and itchy skin patches. It occurs when an overactive immune system responds aggressively to exposed irritants. It usually affects the inner elbows, arms, back of knees or head but can occur anywhere. Eczema is not contagious. Scratching irritates and inflames the skin, which may cause infections which must be treated with antibiotics. The symptoms include itchy, dry, flakey, swollen, rough and irritated skin.

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