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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Composition :

TACROLIMUS-0.50MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tacrotor 0.5Mg Capsule

Tacrotor 0.5Mg Capsule belongs to a class of drugs called immunosuppressants used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Tacrotor 0.5Mg Capsule contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thus, prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Take Tacrotor 0.5Mg Capsule as prescribed. You are advised to use Tacrotor 0.5Mg Capsule for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of Tacrotor 0.5Mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacrotor 0.5Mg Capsule. Avoid alcohol consumption with Tacrotor 0.5Mg Capsule. Drive only if you are alert, as Tacrotor 0.5Mg Capsule may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking Tacrotor 0.5Mg Capsule. Tacrotor 0.5Mg Capsule may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of Tacrotor 0.5Mg Capsule

Prevent transplanted organ rejection

Directions for Use

Capsule: Take the capsule as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Granules: The granules should be mixed with water to make an oral suspension. Drink the prepared suspension immediately. Do not save the suspension for later use.

Medicinal Benefits

Tacrotor 0.5Mg Capsule contains Tacrolimus, an immunosuppressant used to prevent organ rejection after a transplant. Tacrotor 0.5Mg Capsule suppresses the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tacrotor 0.5Mg Capsule

  • Nausea
  • Diarrhoea
  • Headache
  • Kidney problems
  • Infection
  • Constipation
  • Fever
  • High blood pressure

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacrotor 0.5Mg Capsule. Avoid alcohol consumption with Tacrotor 0.5Mg Capsule. Drive only if you are alert, as Tacrotor 0.5Mg Capsule may cause vision problems or nervous disturbances in some people. If you are about to get vaccinated, inform your doctor before taking Tacrotor 0.5Mg Capsule. Tacrotor 0.5Mg Capsule may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking Tacrotor 0.5Mg Capsule, you are advised to wear protective clothing and sunscreen while going out. You are recommended to use glass or metal materials to prepare the oral suspension. Avoid using plastic (PVC) materials to prepare the suspension as the granules will stick to a plastic container, and your child may not receive their full dose. Do not inhale or let the granules or prepared oral suspension come in contact with your skin or eyes. In case of accidental contact with skin, wash the area well with soap and water, and if it comes in contact with the eyes, rinse with plain water.

Drug-Drug Interactions

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TacrolimusMifepristone
Critical
TacrolimusZiprasidone
Critical

Drug-Drug Interactions

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TacrolimusMifepristone
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule with Mifepristone may significantly increase the blood levels of Tacrotor 0.5Mg Capsule, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusCidofovir
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking cidofovir with Tacrotor 0.5Mg Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule with Ziprasidone can increase the risk of irregular heart rhythm

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusDronedarone
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusThioridazine
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Combining Tacrotor 0.5Mg Capsule with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacrotor 0.5Mg Capsule with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusBedaquiline
Severe
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule together with bedaquiline can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Tacrotor 0.5Mg Capsule and bedaquiline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
TacrolimusInfliximab
Severe
How does the drug interact with Tacrotor 0.5Mg Capsule:
Taking Tacrotor 0.5Mg Capsule together with infliximab may increase the risk of serious infections.

How to manage the interaction:
Although taking Tacrotor 0.5Mg Capsule and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
TacrolimusClarithromycin
Severe
How does the drug interact with Tacrotor 0.5Mg Capsule:
Clarithromycin may boost the blood levels of Tacrotor 0.5Mg Capsule increasing the risk of kidney problems, high blood sugars, high potassium levels in the blood, high blood pressure, irregular heart rhythm, and infections.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Tacrotor 0.5Mg Capsule if prescribed by the doctor. However, consult the doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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TACROLIMUS-0.50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-0.50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacrotor 0.5Mg Capsule treatment may lead to increased Tacrotor 0.5Mg Capsule levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacrotor 0.5Mg Capsule.

Diet & Lifestyle Advise

Kidney transplant:

  • Include fruits and vegetables in your daily routine.
  • Follow a vitamin-C-rich diet.
  • Reduce salt intake.
  • Eat a handful of walnuts and almonds every day.
  • Reduce intake of unhealthy cholesterol and fats.
  • Consume dark chocolate with at least 70% cocoa.

Liver and Heart transplant:

  • Eat whole-grain bread, cereals and other grains, fruits and vegetables, lean meats, fish and poultry.
  • Maintain a low-fat and low-salt diet.
  • Drink low-fat milk or eat other low-fat dairy products to maintain adequate calcium.
  • Stay hydrated by drinking sufficient water and other fluids.
  • Avoid alcohol consumption.
  • Avoid grapefruit and grapefruit juice. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Tacrotor 0.5Mg Capsule Substitute

Substitutes safety advice
  • Alagraf 0.5Mg Capsule 10'S

    by AYUR

    16.34per tablet
  • Renelimus-0.5 Capsule 10's

    by Others

    18.54per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tacrotor 0.5Mg Capsule contains Tacrolimus, an immunosuppressant that works by the activity of T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Tacrotor 0.5Mg Capsule may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as sore throat or fever.

Tacrotor 0.5Mg Capsule may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Tacrotor 0.5Mg Capsule because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Tacrotor 0.5Mg Capsule with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Tacrotor 0.5Mg Capsule with other medications.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • SIROLIMUS
  • NELFINAVIR
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TRIAMTERENE
  • AMILORIDE

Special Advise

Regular blood tests and certain other tests are recommended while taking Tacrotor 0.5Mg Capsule to check blood sugar levels, kidney functioning and potassium levels in the blood.

Disease/Condition Glossary

Organ rejection: It occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it. Organ rejection may be hyperacute (occurs in minutes to hours), acute (occurs within the first few months), or chronic (occurs after a year or anytime beyond). The symptoms of organ rejection may vary based on the type of organ transplant you have had. However, if you experience pain, fever, or other signs of illness, contact your doctor immediately.

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