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Whats That
About Tecentriq 840 mg Injection
Tecentriq 840 mg Injection is an anti-cancer medicine used in the treatment of unresectable, stage II-IIIa non-small cell lung cancer (NSCLC). Tecentriq 840 mg Injection is also used in combination with other cancer medicine for the treatment of metastatic NSCLC (bevacizumab, paclitaxel, carboplatin), extensive-stage small cell lung cancer and biliary tract cancer (carboplatin, etoposide), metastatic melanoma (cobimetinib, vemurafenib), and unresectable hepatocellular cancer (bevacizumab).
Tecentriq 840 mg Injection contains Atezolizumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the action of a programmed death ligand receptor-1 (PD-L1), thereby stopping the abnormal growth of cancer cells.
Tecentriq 840 mg Injection may cause certain side effects such as fatigue, cough, diarrhoea, nausea, vomiting, tiredness, itching, rash, headache, fever, shortness of breath, muscle/joint pain, abdominal pain, loss of appetite and injection site reactions. Inform your doctor if any of these side effects persist for longer. Tecentriq 840 mg Injection will be administered by an oncologist trained in administering anti-cancer agents.
Avoid receiving Tecentriq 840 mg Injection and inform your doctor if you are allergic to it or any other components of it. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this Tecentriq 840 mg Injection. Before starting treatment with Tecentriq 840 mg Injection, tell your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis or Crohn's disease, a history of organ transplants, received an allogeneic stem cell transplant, or had radiation treatment to the chest, and myasthenia gravis.
Uses of Tecentriq 840 mg Injection
Directions for Use
Medicinal Benefits
Tecentriq 840 mg Injection contains Atezolizumab, which is used in the treatment of different types of cancers. It works by inhibiting the action of a programmed death ligand receptor-1 (PD-L1) that causes the multiplication of cancer cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other body parts.
Storage
Drug Warnings
To treat your condition effectually, continue receiving Tecentriq 840 mg Injection for the period that your doctor has prescribed. Tecentriq 840 mg Injection may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis, hepatotoxicity, nephritis, endocrinopathies, pneumonitis, cardiac problems, and dermatologic reactions. It may also cause infusion-related reactions in some patients. Therefore, caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, gastrointestinal disorders, autoimmune disorders such as ulcerative colitis or Crohn’s disease, lung disease, heart problems, and breathing difficulty while receiving Tecentriq 840 mg Injection. This medicine may also cause severe infusion-related reactions. Hence, careful monitoring is recommended and discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Side Effects of Tecentriq 840 mg Injection
Habit Forming
Therapeutic Class
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Drug-Diseases Interactions
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Tecentriq 840 mg Injection contains Atezolizumab, which works by inhibiting the action of a programmed death receptor-1 (PD-L1) that causes the multiplication of cancerous cells.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
Non-Small Cell Lung Cancer (NSCLC): It is the most common form of lung cancer, which occurs when cells that form the lining of the lung start growing uncontrollably. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.
Hepatocellular carcinoma: It occurs when the cancer/ malignant cells grow out of control in the liver. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions.
Biliary tract cancer: Also known as bile duct cancer or Cholangiocarcinoma. It is a rare type of cancer in which the cancer cells grow abnormally in the epithelial cells lining the biliary tract. Symptoms may include abdominal pain, itching, fever, weight loss, changes in the colour of urine and stools, and jaundice.
Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. Tecentriq 840 mg Injection is used in combination with ipilimumab in adults and children above 12 years of age.
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Alcohol
Consult your doctor
It is unknown whether Tecentriq 840 mg Injection interacts with alcohol. Consult your doctor for more information.
Pregnancy
Unsafe
Tecentriq 840 mg Injection is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning to be pregnant, inform your doctor before receiving Tecentriq 840 mg Injection. You should not become pregnant while you are receiving Tecentriq 840 mg Injection for at least five months from the last dose of Tecentriq 840 mg Injection. Using effective birth control methods while on treatment is suggested.
Breast Feeding
Unsafe
Tecentriq 840 mg Injection should not be taken if you are breastfeeding, as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine and for at least five months from the last dose of medicine.
Driving
Not applicable
Tecentriq 840 mg Injection will be administered to hospitalized patients. Driving is not recommended.
Liver
Caution
If you have pre-existing or a history of liver problems, tell your doctor before receiving this medicine. Inform your doctor if you experience any symptoms, such as severe nausea or vomiting, right-sided upper stomach pain, easy bruising or bleeding, dark urine, or jaundice (yellowing of the skin or eyes). Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.
Kidney
Caution
If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Tecentriq 840 mg Injection. Tell your doctor if you have little or no urination, swelling in your feet or ankles, or blood in your urine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Unsafe
Tecentriq 840 mg Injection is not recommended for use in children under 12 years old as the safety and efficacy are not established.