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  3. Tepmetko 225 mg Tablet 30's

Tepmetko 225 mg Tablet 30's, Pack of 1 TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

TEPOTINIB-225MG

Manufacturer/Marketer :

Merck Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tepmetko 225 mg Tablet

Tepmetko 225 mg Tablet belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer that has progressed to other body regions or cannot be removed surgically. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues.

Tepmetko 225 mg Tablet contains Tepotinib. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

To treat your condition effectually, continue using Tepmetko 225 mg Tablet for as long as your doctor has prescribed it. The most common adverse reactions are oedema (swelling), fatigue (tiredness), diarrhoea, musculoskeletal pain, dyspnea (shortness of breath), feeling sick (nausea), being sick (vomiting), diarrhoea and QT prolongation. You should talk to your doctor if you persistently experience these side effects.

Inform your doctor if you are allergic to it or have ILD (Interstitial lung disease)/pneumonitis (inflammation in your lung tissues without an infection). Tepmetko 225 mg Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Tepmetko 225 mg Tablet . Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Tepmetko 225 mg Tablet

Lung cancer (non-small cell lung cancer)

Directions for Use

Tepmetko 225 mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Medicinal Benefits

Tepmetko 225 mg Tablet contains Tepotinib, which belongs to a class of protein kinase inhibitors primarily used to manage or treat adults with lung cancer that has progressed to other regions of the body or cannot be removed surgically. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

Drug Warnings

Before taking the Tepmetko 225 mg Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Tepotinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Tepotinib and for at least one week after the last dose. Do not use any other medicine, including herbal or vitamin supplements, unless the doctor suggests.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

KINASE INHIBITORS

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Tepmetko 225 mg Tablet contains Tepotinib, a protein kinase inhibitor that works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

Tepmetko 225 mg Tablet may lead to a change in the heart's electrical activity (QT prolongation). Your doctor conducts ECG tests during treatment to check whether Tepmetko 225 mg Tablet affects your heart rhythm.

It is critical to understand that Tepotinib is not a traditional chemotherapy drug and functions in a different manner. It works by specifically targeting cancer cells and preventing their growth and spread.

While taking Tepmetko 225 mg Tablet , make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Tepmetko 225 mg Tablet .

Fertility studies of Tepotinib have not been performed. Discuss the risks of taking this medication with your doctor.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • QUINIDINE
  • VERAPAMIL
  • RITONAVIR
  • NELFINAVIR
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • ST JOHN'S WORT

Special Advise

  • Keep all of your doctor's and laboratory appointments.
  • Pregnancy testing is recommended prior to starting treatment with Tepmetko 225 mg Tablet .

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Lung cancer: Lung cancer is one of the most common and serious types of cancer. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues. Primary lung cancer is cancer that begins in the lungs. Secondary lung cancer is cancer that spreads to the lungs from elsewhere in the body. There are usually no signs or symptoms in the early stages of lung cancer. Still, many people experience symptoms such as a chronic cough, coughing up blood, persistent dyspnea, unexplained tiredness and weight loss, and an ache or pain when breathing or coughing.

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