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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
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Composition :

MEPHENTERMINE-30MG

Manufacturer/Marketer :

VARENYAM HEALTHCARE PVT LTD

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Termiva 30Mg/Ml Inj

Termiva 30Mg/Ml Inj belongs to a category of medications called ‘Antihypotensives’ primarily used to treat hypotension (low blood pressure). Besides this, Termiva 30Mg/Ml Inj is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension. Hypotension is a condition when blood pressure drops below the normal range, which may reduce cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and a risk of injury from falls.

Termiva 30Mg/Ml Inj contains ‘Mephentermine’ is a class of medicines called sympathomimetic. It helps to release a chemical messenger (adrenaline), which compresses the blood vessels. It increases blood pressure rapidly by increasing the pumping capacity of the heart and narrowing the blood vessels of the heart.  Hence, it works to increase your blood pressure.

Termiva 30Mg/Ml Inj will be administered by a healthcare professional. Do not self-administer Termiva 30Mg/Ml Inj. Some people may experience systemic hypertension (high blood pressure), anxiety, insomnia (difficulty in sleeping), and CNS stimulation. Most of these side effects of Termiva 30Mg/Ml Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Termiva 30Mg/Ml Inj. It should not be used in children below 18 years. Termiva 30Mg/Ml Inj should be used with caution in patients with having heart disease, overactive thyroid, shock, dehydration, or acidosis (increased acid level in blood). Do not take Termiva 30Mg/Ml Inj if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. If you have high blood pressure, kidney or liver problems, or coronary artery disease, inform your doctor before taking Termiva 30Mg/Ml Inj.

Uses of Termiva 30Mg/Ml Inj

Hypotension (low blood pressure)

Directions for Use

Termiva 30Mg/Ml Inj will be administered by a healthcare professional. Do not self-administer Termiva 30Mg/Ml Inj.

Medicinal Benefits

Termiva 30Mg/Ml Inj consists of Mephentermine is a sympathomimetic medicine. It helps to release a chemical messenger (adrenaline), which compresses the blood vessels. It increases the blood pressure rapidly by increasing the pumping capacity of the heart and narrowing the blood vessels of the heart.  Hence, it works to increase your blood pressure. Termiva 30Mg/Ml Inj also used by anesthesiologist and intensive care specialist to treat hypotension (decreased blood pressure) due to vasodilation caused by general, epidural, and spinal anesthesia (caesarian section).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tell your doctor if you are allergic to Termiva 30Mg/Ml Inj, or any of its ingredients. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines, and herbal supplements. Termiva 30Mg/Ml Inj is not recommended during pregnancy or breastfeeding unless prescribed by a doctor. Termiva 30Mg/Ml Inj should not be given to children as safety and effectiveness have not been established. Before using Termiva 30Mg/Ml Inj, tell your doctor if you have liver/kidney problems, hypertension, overactive thyroid, shock, dehydration, acidosis. Do not drive or handle machinery unless you are alert. Termiva 30Mg/Ml Inj is not recommended in the treatment of hypotension (low blood pressure) induced by chlorpromazine because it may potentiate, rather than correct. Inform your doctor if you are taking or have recently taken medication to treat severe depression.  

Drug-Drug Interactions

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MephentermineIsocarboxazid
Critical

Drug-Drug Interactions

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MephentermineIsocarboxazid
Critical
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
Taking isocarboxazid and Termiva 30Mg/Ml Inj 10Ml together can increase the risk of high blood pressure.

How to manage the interaction:
Taking Termiva 30Mg/Ml Inj 10Ml with Isocarboxazid is not recommended, but can be taken if prescribed by the doctor. However, consult your doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
Taking linezolid and Termiva 30Mg/Ml Inj 10Ml together may cause high blood pressure.

How to manage the interaction:
Taking Termiva 30Mg/Ml Inj 10Ml with Linezolid is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
When Termiva 30Mg/Ml Inj 10Ml is combined with Selegiline, may increase the risk of high blood pressure.

How to manage the interaction:
Termiva 30Mg/Ml Inj 10Ml with Selegiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
Taking Procarbazine with Termiva 30Mg/Ml Inj 10Ml together may increase the hypertensive activities of Termiva 30Mg/Ml Inj 10Ml.

How to manage the interaction:
Taking Termiva 30Mg/Ml Inj 10Ml with Procarbazine is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
MephenterminePhenelzine
Critical
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
Taking Phenelzine with Termiva 30Mg/Ml Inj 10Ml together may increase the hypertensive activities of Termiva 30Mg/Ml Inj 10Ml.

How to manage the interaction:
Taking Termiva 30Mg/Ml Inj 10Ml with Phenelzine together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these signs - headache, trouble seeing clearly, feeling confused or having seizures, chest pain, feeling sick, sudden numbness or weakness, difficulty speaking, having a fever, sweating a lot, feeling dizzy or passing out - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
MephentermineIobenguane (131i)
Severe
How does the drug interact with Termiva 30Mg/Ml Inj 10Ml:
Co-administration of Iobenguane (131i) and Termiva 30Mg/Ml Inj 10Ml together can decrease the effectiveness of Termiva 30Mg/Ml Inj 10Ml.

How to manage the interaction:
There may be a possibility of interaction between Termiva 30Mg/Ml Inj 10Ml and Iobenguane (131i), but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add foods with high vitamin B12, including eggs, fortified cereals, and nutritional yeast to your daily diet.
  • Salty foods can increase blood pressure. Try eating canned soup, cottage cheese, olives, and pickled items.
  • Drink coffee and caffeinated tea; it may spike blood pressure by stimulating the cardiovascular system.
  • Eat small meals more frequently; large meals may drop in blood pressure as your body works harder to digest larger meals.
  • Drink more water and limit alcohol; dehydration lowers blood pressure.
  • Change body position standing up slowly.
  • Avoid prolonged bed rest.
  • If you exercise outdoors in extreme heat, take frequent breaks.
  • Avoid spending a long time in saunas, hot tubs, and steam rooms which cause dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Do not stop taking Termiva 30Mg/Ml Inj on your own. You are advised to take Termiva 30Mg/Ml Inj for as long as your doctor has prescribed it for you depending on your medical condition. Do not be hesitant to speak with your doctor if you experience any difficulty while taking Termiva 30Mg/Ml Inj.

Do not take Termiva 30Mg/Ml Inj if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Termiva 30Mg/Ml Inj only if the benefits outweigh the risks.

Antidepressants, along with Termiva 30Mg/Ml Inj, especially monoamine oxidase inhibitors (MAOI’s) may prolong and increase the effects of Termiva 30Mg/Ml Inj. Consult your doctor before taking Termiva 30Mg/Ml Inj with other medicines to avoid unpleasant side-effects.

Systemic hypertension (high blood pressure), Anxiety, Insomnia (difficulty in sleeping), CNS stimulation are the common side-effects of Termiva 30Mg/Ml Inj. 

A person should tell their doctor if they have a history of heart disease, overactive thyroid, shock, high blood pressure, persistent and lasting illness, during pregnancy, and breastfeeding.

Drug-Drug Interactions Checker List

  • AMPHETAMINE
  • DEXTROAMPHETAMINE
  • GUAIFENESIN+BROMHEXINE
  • PHENYLEPHRINE
  • LEVOTHYROXINE SODIUM
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Special Advise

Do not take Termiva 30Mg/Ml Inj if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days; it may cause serious drug interaction.

Disease/Condition Glossary

Hypotension: Low blood pressure is a condition when blood pressure drops below the normal range, which may reduce cardiac output and hypovolemia (low blood volume). It can cause dizziness, weakness, fainting, and a risk of injury from falls. Also, severely low blood pressure can deprive your body of enough oxygen to carry out its functions, leading to damage to your heart and brain. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. Ideal blood pressure should be 120/80 mmHg. Hypotension exists when the systolic pressure is less than 90 mmHg, and the diastolic pressure is less than 60 mmHg. 

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